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DeepHipp: accurate segmentation of hippocampus using 3D dense-block based on attention mechanism
BackgroundThe hippocampus is a key area of the brain responsible for learning, memory, and other abilities. Accurately segmenting the hippocampus and...
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Perinatal compromise affects development, form, and function of the hippocampus part two; preclinical studies
AbstractThe hippocampus is a vital brain structure deep in the medial temporal lobe that mediates a range of functions encompassing emotional...
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Functional specialization and interaction in the amygdala-hippocampus circuit during working memory processing
Both the hippocampus and amygdala are involved in working memory (WM) processing. However, their specific role in WM is still an open question. Here,...
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Developmental dynamics of the single nucleus regulatory landscape of pig hippocampus
The hippocampus is a brain region associated with memory, learning and spatial navigation, its aging-related dysfunction is a common sign of...
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The functional and structural changes in the hippocampus of COVID-19 patients
Since the hippocampus is predominantly susceptible to injuries caused by COVID-19, there are increasing data indicating the likelihood of...
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Perinatal compromise affects development, form, and function of the hippocampus part one; clinical studies
AbstractThe hippocampus is a neuron-rich specialised brain structure that plays a central role in the regulation of emotions, learning and memory,...
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Hippocampus Shape Analysis via Skeletal Models and Kernel Smoothing
Skeletal representations (s-reps) have been successfully adopted to parsimoniously parametrize the shape of three-dimensional objects and have been...
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Conserved role for PCBP1 in altered RNA splicing in the hippocampus after chronic alcohol exposure
We previously discovered using transcriptomics that rats undergoing withdrawal after chronic ethanol exposure had increased expression of several...
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An improved 3D-UNet-based brain hippocampus segmentation model based on MR images
ObjectiveAccurate delineation of the hippocampal region via magnetic resonance imaging (MRI) is crucial for the prevention and early diagnosis of...
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Propensity score-matched analysis comparing hippocampus-avoidance whole-brain radiotherapy plus simultaneous integrated boost with hippocampus‑avoidance whole-brain radiotherapy alone for multiple brain metastases-a retrospective study in multiple institutions
BackgroundThe optimal treatment for multiple brain metastases has been recently controversially discussed.This study was aimed to explore the...
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Sex difference in brain functional connectivity of hippocampus in Alzheimer’s disease
Alzheimer’s disease (AD), affecting nearly 6.5 million people, is the fifth leading cause of death in individuals 65 years or older in the USA. Prior...
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Nitroxidergic and Calretinin-Containing Nonpyramidal Neurons of Rat Hippocampus
Abstract—Unlike pyramidal neurons, interneurons of the hippocampus are a heterogeneous group of neurons that differ in their morphological,...
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Disfunction of dorsal raphe nucleus-hippocampus serotonergic-HTR3 transmission results in anxiety phenotype of Neuroplastin 65-deficient mice
Anxiety disorders are the most common psychiatric condition, but the etiology of anxiety disorders remains largely unclear. Our previous studies have...
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Hippocampus Segmentation Using Fuzzy C Means-Based Level Set Local Ternary Pattern with Enhanced Edge Indicator
The hippocampus segmentation plays a crucial role in analyzing brain activities, which is a widely used biomarker for Alzheimer’s disease, epilepsy,...
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Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice
While patients with cancer show a higher prevalence of psychiatric disorders than the general population, the mechanism underlying this interaction...
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Time-dependent memory transformation in hippocampus and neocortex is semantic in nature
Memories undergo a time-dependent neural reorganization, which is assumed to be accompanied by a transformation from detailed to more gist-like...
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Altered DTI scalars in the hippocampus are associated with morphological and structural changes after traumatic brain injury
Blunt and diffuse injury is a highly prevalent form of traumatic brain injury (TBI) which can result in microstructural alterations in the brain. The...
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Clinical Correlation of Altered Molecular Signatures in Epileptic Human Hippocampus and Amygdala
Widespread alterations in the expression of various genes could contribute to the pathogenesis of epilepsy. The expression levels of various genes,...
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A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise
Exercise has been recognized as a beneficial factor for cognitive health, particularly in relation to the hippocampus, a vital brain region...
