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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Mitochondrial DNA abundance in blood is associated with Alzheimer’s disease- and dementia-risk
The mitochondrial cascade hypothesis of Alzheimer’s disease (AD) has been portrayed through molecular, cellular, and animal studies; however large...
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Critical Care of Spinal Cord Injury
Purpose of ReviewSpinal cord injury (SCI) is a major cause of morbidity and mortality, posing a significant financial burden on patients and the...
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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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Pandemic Paranoia Scale for Adolescents (PPS-A): An Initial Psychometric Evaluation and Prevalence Study of Adolescents in the United States and United Kingdom
Paranoid thoughts have been reported in 20–30% of adolescents, and preliminary research has shown that paranoia and psychotic-like experiences have...
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Progressive multifocal leukoencephalopathy and spectrum of predisposing conditions: a 20-year retrospective cohort study in a tertiary center in São Paulo, Brazil
BackgroundEpidemiological studies on predisposing conditions and outcomes of progressive multifocal leukoencephalopathy (PML) cases have been carried...
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Embelin Mitigates Amyloid-β-Induced Neurotoxicity and Cognitive Impairment in Rats: Potential Therapeutic Implications for Alzheimer’s Disease
Alzheimer’s disease (AD) is a significant form of dementia. Embelin (EMB) is a natural compound with varied actions that could help prevent AD...
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Responsiveness and minimal important change of specific and generic patient-reported outcome measures for back patients: the Norwegian Neck and Back Register
PurposeTo evaluate responsiveness and minimal important change (MIC) of Oswestry Disability Index (ODI), pain during activity on a numeric rating...
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Presence of compensatory curve predicts postoperative curve progression in congenital scoliosis after thoracolumbar hemivertebra resection and short fusion
PurposeTo investigate the impact of preoperative compensatory curve on the postoperative curve progression in congenital scoliosis (CS) patients...
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An insight into the therapeutic effects of isoliquiritigenin in breast cancer
Breast cancer ranks as the most widespread malignant condition in women, emerging as a primary contributor to mortality. The primary challenges in...
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Outpatient reception via collaboration between nurses and a large language model: a randomized controlled trial
Reception is an essential process for patients seeking medical care and a critical component influencing the healthcare experience. However, current...
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Methane-rich saline ameliorates depressive-like behaviors during chronic unpredictable mild stress (CUMS)
Depression, considered the most prevalent neuropsychiatric disorder, is multifactorial and complex. Oxidative stress and inflammation significantly...
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Mid-term clinical effect of resecting posterior longitudinal ligament in anterior approach for cervical spondylosis with sympathetic symptoms: retrospective cohort analysis
Study Design: Retrospective cohort analysis. Objective: The purpose of this study is to investigate whether the removal of the posterior longitudinal...
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Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders
Psychiatric disorders such as Bipolar disorder, Anxiety, Major depressive disorder, Schizophrenia, Attention-deficit/hyperactivity disorder, as well...
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The aneurysm occlusion and recurrence of posterior communicating artery aneurysms following the treatment with the pipeline embolization device
Despite advancements in treatment modalities such as flow diverters, the optimal management of posterior communicating artery (PComA) aneurysms...
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FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury
This study elucidates the molecular mechanisms by which FABP3 regulates neuronal apoptosis via mitochondrial autophagy in the context of cerebral...
