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Unveiling the distinctive mechanical and thermal properties of γ-GeSe
γ-GeSe is a newly identified polymorph among group-IV monochalcogenides, characterized by a distinctive interatomic bonding configuration. Despite...
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Advances in Black Phosphorus Quantum Dots for Cancer Research: Synthesis, Characterization, and Applications
In the past few years, there has been notable advancement in nanotechnology, leading to the development of new materials with potential uses in the...
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Synergistic improvement of erosion-corrosion resistance and mechanical properties of nickel aluminium bronze alloy by the addition of Cr
The effect of Cr addition on nickel aluminium bronze (NAB) alloy microstructure, mechanical properties, and erosion-corrosion behaviour has been...
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Enhanced strength–plasticity synergy of copper composites by designing uniformly dispersed yttria nanoparticles and a heterogeneous grain structure
Designing heterogeneous grain structure (HGS) has been proven to be an effective strategy for overcoming the strength-plasticity dilemma in copper...
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Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF...
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Exploring the electronic structure of knotted proteins: the case of two ornithine transcarbamylase family
Context:Geometrical knots are rare structural arrangements in proteins in which the polypeptide chain ties itself into a knot, which is very...
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Design and Validation of Novel Potential Antiperspirant Peptides Blocking M3-Gαq Sweat Signaling Cascade
Sweat production is vital for human survival as its evaporation eases heat dissipation. Nevertheless, excessive perspiration or hyperhidrosis causes...
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A modeling strategy investigation for selective hydrodeoxygenation biomass upgrading of vanillin via metal supported on pyridinic and pyrrolic nitrogen-doped carbon catalysts
To extend the practical application of biomass upgrading conversion to liquid fuel, it is crucial to develop highly catalytic and reversible...
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Nanomaterial-Based Repurposing of Macrophage Metabolism and Its Applications
Macrophage immunotherapy represents an emerging therapeutic approach aimed at modulating the immune response to alleviate disease symptoms....
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Preclinical evaluation of CXCR4 peptides for targeted radionuclide therapy in glioblastoma
BackgroundGlioblastoma (GBM), is the most fatal form of brain cancer, with a high tendency for recurrence despite combined treatments including...
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Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies
BackgroundChildhood epilepsies are caused by heterogeneous underlying disorders where approximately 40% of the origins of epilepsy can be attributed...
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Identifying early symptoms associated with a diagnosis of childhood, adolescent and young adult cancers: a population-based nested case-control study
BackgroundChildhood, teenage and young adult (CTYA, 0–24 years) cancers are rare and diverse, making timely diagnosis challenging. We aim to explore...
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Biophysical characterization of the phase separation of TDP-43 devoid of the C-terminal domain
BackgroundFrontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-TDP), amyotrophic lateral sclerosis (ALS) and limbic-predominant...
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Effect of annealing temperature on the optoelectrical synapse behaviors of A-ZnO microtube
Optoelectronic synapses with fast response, low power consumption, and memory function hold great potential in the future of artificial intelligence...
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Cell-cell contact-dependent secretion of large-extracellular vesicles from EFNBhigh cancer cells accelerates peritoneal dissemination
BackgroundLarge non-apoptotic vesicles released from the plasma membrane protrusions are classified as large-EVs (LEVs). However, the triggers of LEV...
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Effect of α7 nAChR-autophagy axis of deciduous tooth pulp stem cells in regulating IL-1β in the process of physiological root resorption of deciduous teeth
AbstractPhysiological root resorption of deciduous teeth is a normal phenomenon occurring during the developmental stages of children. Previous...
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Laser additive manufacturing of titanium alloys: process, materials and post-processing
Laser additive manufacturing (LAM) of titanium (Ti) alloys has emerged as a transformative technology with vast potential across multiple industries....