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The C-terminal region of the Plasmodium berghei gamete surface 184-kDa protein Pb184 contributes to fertilization and male gamete binding to the residual body
BackgroundMalaria, a global health concern, is caused by parasites of the Plasmodium genus, which undergo gametogenesis in the midgut of mosquitoes...
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Enhancing Phosphate Uptake and Antifungal Activity in Tomato Plants via Bacillus licheniformis Mutagenesis: Evaluating Growth Parameters
The objective of the investigation was to improve phosphate solubilization in tomato plants by Bacillus licheniformis , a rhizobacterium that promotes...
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First Insight into the Phylogenetic Diversity of Bovicola caprae Infesting Goats of Different Agro-climatic Locations in India
Bovicola caprae is an important obligate ectoparasite of goats worldwide including India. The present study aimed at the molecular confirmation,...
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Malaria prevalence and transmission in the Zakpota sub-district of central Benin: baseline characteristics for a community randomised trial of a new insecticide for indoor residual spraying
BackgroundMalaria transmission is known to be perennial and heterogeneous in Benin. Studies assessing local malaria prevalence, transmission levels...
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Development and validation of nomogram for predicting the risk of transferring to the ICU for children with influenza
ObjectiveDevelopment of a nomogram model for predicting the magnitude of risk of transferring hospitalized children with influenza to the ICU.
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Assessing seropositivity of MMR antibodies in individuals aged 2–22: evaluating routine vaccination effectiveness after the 2003 mass campaign-a study from Iran’s National Measles Laboratory
Background and purposeThe seroprevalence of antibodies against measles, mumps, and rubella (MMR) was evaluated 17 years following a mass vaccination...
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Orchestration of antiviral responses within the infected central nervous system
Many newly emerging and re-emerging viruses have neuroinvasive potential, underscoring viral encephalitis as a global research priority. Upon entry...
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Identification of a novel member of the genus Laulavirus (family Phenuiviridae) from the entomopathogenic ascomycete fungus Cordyceps javanica
The virus family Phenuiviridae (order Hareavirales , comprising segmented negative-sense single stranded RNA viruses) has highly diverse members that...
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Antimicrobial susceptibility profile of ceftolozane/tazobactam, ceftazidime/avibactam and cefiderocol against carbapenem-resistant Pseudomonas aeruginosa clinical isolates from Türkiye
PurposeCarbapenem resistant Pseudomonas aeruginosa (CR-PA) is escalating worldwide and leaves clinicians few therapeutic options in recent years,...
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Comparative genomics of Vibrio toranzoniae strains
Vibrio toranzoniae is a marine bacterium belonging to the Splendidus clade that was originally isolated from healthy clams in Galicia (NW Spain). Its...
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A dynamic subpopulation of CRISPR–Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage
Many CRISPR–Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein) systems, which provide bacteria with...
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Optimization of Total DNA Extraction from Dried Blood Samples
While dried blood spots are a convenient source of genetic material, they are usually associated with a lower DNA yield than from a native sample....
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A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications
Approved vaccines are effective against severe COVID-19, but broader immunity is needed against new variants and transmission. Therefore, we...
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Bacterial reprogramming of tick metabolism impacts vector fitness and susceptibility to infection
Arthropod-borne pathogens are responsible for hundreds of millions of infections in humans each year. The blacklegged tick, Ixodes scapularis , is the...
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A wingless fly on a winged mammal: host-parasite dynamics between Basilia travassosi (Diptera: Nycteribiidae) and Myotis lavali (Chiroptera: Vespertilionidae)
Nycteribiidae encompasses a specialized group of wingless blood-sucking flies that parasitize bats worldwide. Such relationships are frequently...
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Non-falciparum malaria infections in Uganda, does it matter? A review of the published literature
BackgroundPlasmodium falciparum is the dominant malaria species in the sub-Saharan Africa and the main cause of severe disease and death....
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Develo** a genomic-based strategy to confirm microbial identity in bio-inputs containing multiple strains: an easy, fast, and low-cost multiplex PCR applied to inoculants carrying soybean Bradyrhizobium
Brazil stands out in research, industrial development, and farmers' use of microbial inoculants, with an emphasis on getting benefits from the...
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First detection and a new avian host of the tick Ixodes ventalloi Gil Collado, 1936, in Slovakia
This study describes the first detection of Ixodes ventalloi in Slovakia. Two engorged females of I. ventalloi were collected from Dunnocks ( Prunella...
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Identification of HOXC Gene Family as Prognostic and Immune-Related Biomarkers in Breast Cancer Through mRNA Transcriptional Profile and Experimental Validation
Breast cancer (BC) is the most common malignancy in women worldwide, and more effective biomarkers are urgently needed for the prevention and...
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Priming antibody responses to the fusion peptide in rhesus macaques
Immunodominance of antibodies targeting non-neutralizing epitopes and the high level of somatic hypermutation within germinal centers (GCs) required...