Search
Search Results
-
-
Application of 5T glutamate chemical exchange saturation transfer imaging in brain tumors: preliminary results
PurposeGlutamate chemical exchange saturation transfer (GluCEST) is a non-invasive CEST imaging technique for detecting glutamate levels in tissues....
-
Exploring regulatory mechanisms on miRNAs and their implications in inflammation-related diseases
This comprehensive exploration delves into the pivotal role of microRNAs (miRNAs) within the intricate tapestry of cellular regulation. As potent...
-
Functions of methyltransferase-like 3 in breast cancer: pathogenesis, drug resistance, and therapeutic target
Breast cancer (BC) is a highly prevalent malignancy worldwide, with complex pathogenesis and treatment challenges. Research reveals that...
-
Surgical outcomes of novel retroperitoneal low anterior vs posterior and transperitoneal access in single-port partial nephrectomy
PurposeSingle-Port Robot-Assisted Partial Nephrectomy (SP-RAPN) can be performed by transperitoneal and retroperitoneal approaches. However, there is...
-
Targeted delivery of FAK siRNA by engineered exosomes to reverse cetuximab resistance via activating paraptosis in colon cancer
BackgroundCetuximab is extensively used in the treatment of metastatic colorectal cancer (mCRC). However, resistance poses a significant challenge to...
-
Serum Zinc and Copper Concentrations and Dyslipidemia as Risk Factors of Cardiovascular Disease in Adults: Data Mining Techniques
This study aimed to examine the relationship between serum cholesterol levels and the ratio of zinc (Zn) and copper (Cu) in the blood serum and the...
-
Just scratching the surface: novel treatment approaches for multiple myeloma targeting cell membrane proteins
A better understanding of the roles of the adaptive and innate immune systems in the oncogenesis of cancers including multiple myeloma (MM) has led...
-
Cost Offset of Dapagliflozin in the US Medicare Population with Cardio-Kidney Metabolic Syndrome
IntroductionCardiovascular-kidney-metabolic (CKM) syndrome is highly prevalent in the US Medicare population and is projected to increase further....
-
Ectonucleotidase inhibitors: targeting signaling pathways for therapeutic advancement—an in-depth review
Ectonucleotidase inhibitors are a family of pharmacological drugs that, by selectively targeting ectonucleotidases, are essential in altering...
-
Sedation-free pediatric [18F]FDG imaging on totalbody PET/CT with the assistance of artificial intelligence
PurposeWhile sedation is routinely used in pediatric PET examinations to preserve diagnostic quality, it may result in side effects and may affect...
-
Biomarkers to predict efficacy of immune checkpoint inhibitors in colorectal cancer patients: a systematic review and meta-analysis
Immune checkpoint inhibitors (ICIs) are approved to treat colorectal cancer (CRC) with mismatch-repair gene deficiency, but the response rate remains...
-
The predictors of fungal infections after liver transplantation and the influence of fungal infections on outcomes
The primary objective of this study was to assess the incidence, timing, risk factors of fungal infections (FIs) within 3 months after liver...
-
SEOM-GG clinical guidelines for the management of germ-cell testicular cancer (2023)
Testicular germ cell tumors are the most common tumors in adolescent and young men. They are curable malignancies that should be treated with...
-
Molecular pathway of anticancer effect of next-generation HSP90 inhibitors XL-888 and Debio0932 in neuroblastoma cell line
Neuroblastoma is a common nervous system tumor in childhood, and current treatments are not adequate. HSP90 is a molecular chaperone protein that...
-
Preclinical evaluation of [18F]FP-CIT, the radiotracer targeting dopamine transporter for diagnosing Parkinson’s disease: pharmacokinetic and efficacy analysis
BackgroundN -(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT), the representative cocaine derivative used in dopamine...
-
Efficacy of a nurse-led sexual rehabilitation intervention for women with gynaecological cancers receiving radiotherapy: results of a randomised trial
BackgroundThe multicentre randomised SPARC trial evaluated the efficacy of a nurse-led sexual rehabilitation intervention on sexual functioning,...
-
Radiomics and visual analysis for predicting success of transplantation of heterotopic glioblastoma in mice with MRI
BackgroundQuantifying tumor growth and treatment response noninvasively poses a challenge to all experimental tumor models. The aim of our study was,...
