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Interaction between spiders and ticks—ancient arthropod predatory behavior?
Ticks are ectoparasite vectors of pathogens affecting human and animal health worldwide. Rational integration of different control interventions...
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Protective effects of ginsenosides on ulcerative colitis: a meta-analysis and systematic review to reveal the mechanisms of action
BackgroundUlcerative colitis (UC) is a chronic inflammatory disease of the colon. Ginsenoside may be an ideal agent for UC treatment. However, its...
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Validating genetic variants in innate immunity linked to infectious events in acute myeloid leukemia post-induction chemotherapy
Infectious events, such as sepsis and invasive fungal disease (IFD), pose significant risks in patients with acute myeloid leukemia (AML). Previous...
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Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease
Eosinophils are bone marrow-derived granulocytes that are traditionally associated with type 2 immune responses, such as those that occur during...
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IL-27 disturbs lipid metabolism and restrains mitochondrial activity to inhibit γδ T17 cell-mediated skin inflammation
IL-17+ γδ T cells (γδ T17) are kick-starters of inflammation due to their strict immunosurveillance of xenobiotics or cellular damages and rapid...
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Protective and curative effects of unconjugated bilirubin on gene expression of LOX-1 and iNOS in the heart of rats receiving high-fat diet and low dose streptozotocin: a histomorphometric approach
BackgroundAtherosclerosis is a chronic inflammatory condition affecting the large arteries and is a major cause of cardiovascular diseases (CVDs)...
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Exploring the complex associations among risks of malnutrition, sarcopenia, and frailty in community-dwelling older adults
BackgroundMalnutrition, sarcopenia, and frailty are age-related conditions that are associated with multiple health-related negative outcomes....
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Caspase-3 promotes oncogene-induced malignant transformation via EndoG-dependent Src-STAT3 phosphorylation
Accumulating evidence suggests that caspase-3 plays critical roles beyond apoptosis, serving pro-survival functions in malignant transformation and...
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Involvement of Kindlin-1 in cutaneous squamous cell carcinoma
Kindler syndrome (KS) is a rare genodermatosis resulting from loss-of-function mutations in FERMT1 , the gene that encodes Kindlin-1. KS patients have...
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Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system
The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and...
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The combination of temozolomide and perifosine synergistically inhibit glioblastoma by impeding DNA repair and inducing apoptosis
Temozolomide (TMZ) is widely utilized as the primary chemotherapeutic intervention for glioblastoma. However, the clinical use of TMZ is limited by...
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Gut microbiota regulation of T lymphocyte subsets during systemic lupus erythematosus
BackgroundSystemic lupus erythematosus (SLE) is an autoimmune disease characterized by disturbance of pro-inflammatory and anti-inflammatory...
