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Scanning Probe Microscopy Studies of Surface-Immobilised DNA/Oligonucleotide Molecules
Although most in vivo biomolecular recognition occurs in solution, in many practical situations (e.g., diagnostics, drug discovery and biosensing)... -
New Phosphorylated Hosts for the Design of New Supramolecular Assemblies
Development of chemistry around new phosphorylated hosts provides an interesting new area of investigations in the design of host-guest systems.... -
Complexes with a Metal-Phosphorus Triple Bond
A survey of the existing complexes containing a transition metal-phosphorus triple bond is presented. Based on the different types of these... -
Bioprocess Monitoring Using Near-Infrared Spectroscopy
Near-infrared spectroscopy (NIR) is a nondestructive analytical technique that has been used for simultaneous prediction of the concentrations of... -
Metabolic Flux Analysis Based on 13C-Labeling Experiments and Integration of the Information with Gene and Protein Expression Patterns
The recent progress on metabolic systems engineering was reviewed, in particular focusing on the metabolic flux analysis (MFA) based on the... -
Transgenic Birds for the Production of Recombinant Proteins
Transgenic birds were expected to be an excellent transgenic bioreactor for the production of recombinant pharmaceutical proteins. However, the only... -
Survey of Enzymological Data on ODCase
OMP decarboxylase (ODCase) has been the subject of enzymological, structural, and theoretical studies for several decades, yet its highly proficient... -
Discrete Organic Nanotubes Based on a Combination of Covalent and Non-Covalent Approaches
Tubular organic nanostructures offering precise control over inner and outer surface functionality represent attractive building blocks for the... -
Introduction: Regulatory processes, an emerging feature in intracellular membrane traffic
The subject of this volume is the molecular mechanism of the intracellular membrane trafficking, a central eukaryotic cell biological process. In the... -
Ferrocene–Peptide Bioconjugates
This chapter sketches an outline of ferrocene–peptide bioconjugates. A variety of ferrocene–peptide bioconjugates have been designed to induce... -
Catalytic Nickel–Iron–Sulfur Clusters: From Minerals to Enzymes
The geochemical theory of the origin of life proposes that primordial, pre-biotic reactions were carried out in a metal-sulfide-rich environment... -
Control of Cell Proliferation and Growth by Myc Proteins
Myc proteins act as signal transducers that alter cell proliferation in dependence on signals from the extracellular environment. In normal cells,... -
Carbene Complexes of Heme Proteins and Iron Porphyrin Models
The possible formation of carbene complexes of cytochromes P450 enzymes in various metabolisms of xenobiotics is first described. In view of these... -
The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
Since its discovery in 1986, as the first tumor suppressor gene, the retinoblastoma gene (Rb) has been extensively studied. Numerous biochemical and... -
Comparative genomics and gene finding in fungi -- Supplement
Online Supplement to Chapter 1 -
Present Status of Antifouling Systems in Japan: Tributyltin Substitutes in Japan
An international conference held by the International Maritime Organization in October 2001 adopted an “International convention on the control of... -
New Trends in Sample Preparation Methods for the Determination of Organotin Compounds in Marine Matrices
Tributyltin still remains a major issue for the marine environment and its determination is mandatory by legislation in several countries. As for... -
Microwave-Assisted Synthesis of Sulfur and Nitrogen-Containing Heterocycles
This chapter aims to review recent developments in the synthesis of sulfur and nitrogen-containing heteroaromatic compounds under conditions that... -
Spectroscopic Study of the Structure of Zetekitoxin AB
Zetekitoxin (former name: atelopidtoxin) was reported by Mosher and colleagues in 1969 as a potent, water-soluble, guanidinium toxin found in... -
Applications of Flexible Molecular Descriptors in the QSPR–QSAR Study of Heterocyclic Drugs
Various formulations of optimal descriptors introduced by different authors during the last 10 years are discussed for the special case of...