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Multimodal decoding of human liver regeneration
The liver has a unique ability to regenerate
1 ,2 ; however, in the setting of acute liver failure (ALF), this regenerative capacity is often...
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Interferon-gamma signaling promotes cartilage regeneration after injury
Osteoarthritis is a common chronic disease and major cause of disability and chronic pain in ageing populations. In this pathology, the entire joint...
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Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration
Bone regeneration requires a well-orchestrated cellular and molecular response including robust vascularization and recruitment of mesenchymal and...
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Lithiated porous silicon nanowires stimulate periodontal regeneration
Periodontal disease is a significant burden for oral health, causing progressive and irreversible damage to the support structure of the tooth. This...
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Controlled oxygen delivery to power tissue regeneration
Oxygen plays a crucial role in human embryogenesis, homeostasis, and tissue regeneration. Emerging engineered regenerative solutions call for novel...
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Engineering sulfonate group donor regeneration systems to boost biosynthesis of sulfated compounds
Sulfonation as one of the most important modification reactions in nature is essential for many biological macromolecules to function. Development of...
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Multi-species atlas resolves an axolotl limb development and regeneration paradox
Humans and other tetrapods are considered to require apical-ectodermal-ridge (AER) cells for limb development, and AER-like cells are suggested to be...
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Gli1 marks a sentinel muscle stem cell population for muscle regeneration
Adult skeletal muscle regeneration is mainly driven by muscle stem cells (MuSCs), which are highly heterogeneous. Although recent studies have...
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Occlusive membranes for guided regeneration of inflamed tissue defects
Guided bone regeneration aided by the application of occlusive membranes is a promising therapy for diverse inflammatory periodontal diseases....
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Guidance experiments on residents’ participation in decision-making activities related to urban settlement regeneration in China
In China, how to guide residents on actively participating in decision-making activities related to urban settlement regeneration is critical and...
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Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration
Organ regeneration necessitates precise coordination of accelerators and brakes to restore organ function. However, the mechanisms underlying this...
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Apela promotes blood vessel regeneration and remodeling in zebrafish
In contrast to adult mammals, zebrafish display a high capacity to heal injuries and repair damage to various organs. One of the earliest responses...
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Evolutionarily divergent mTOR remodels translatome for tissue regeneration
An outstanding mystery in biology is why some species, such as the axolotl, can regenerate tissues whereas mammals cannot
1 . Here, we demonstrate that...
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Spatiotemporal transcriptomic atlas reveals the dynamic characteristics and key regulators of planarian regeneration
Whole-body regeneration of planarians is a natural wonder but how it occurs remains elusive. It requires coordinated responses from each cell in the...
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Mechanisms of Wharton’s Jelly-derived MSCs in enhancing peripheral nerve regeneration
Warton’s jelly-derived Mesenchymal stem cells (WJ-MSCs) play key roles in improving nerve regeneration in acellular nerve grafts (ANGs); however, the...
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In situ electrochemical regeneration of nanogap hotspots for continuously reusable ultrathin SERS sensors
Surface-enhanced Raman spectroscopy (SERS) harnesses the confinement of light into metallic nanoscale hotspots to achieve highly sensitive label-free...
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N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration
Translational control is crucial for protein production in various biological contexts. Here, we use Ribo-seq and RNA-seq to show that genes related...
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The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration
As the primary site of T-cell development, the thymus dictates immune competency of the host. The rates of thymus function are not constant, and...
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A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury
Intestinal stem cells (ISCs) maintain the epithelial lining of the intestines, but mechanisms regulating ISCs and their niche after damage remain...
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Next-generation RNA sequencing elucidates transcriptomic signatures of pathophysiologic nerve regeneration
The cellular and molecular underpinnings of Wallerian degeneration have been robustly explored in laboratory models of successful nerve regeneration....
