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Whole-Genome Sequencing of Inbred Mouse Strains Selected for High and Low Open-Field Activity
We conducted whole-genome sequencing of four inbred mouse strains initially selected for high (H1, H2) or low (L1, L2) open-field activity (OFA), and...
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O mouse, where art thou? The Mouse Position Surveillance System (MoPSS)—an RFID-based tracking system
Existing methods for analysis of home cage-based preference tests are either time-consuming, not suitable for group management, expensive, and/or...
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Acoustic Properties and Biological Significance of Ultrasonic Vocalizations in Rodents: Emotional Expressions
In rodents, ultrasonic vocalizations (USVs) are used for communication, and they are widely observed in both wild and laboratory strains. Several...
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Neuropharmacology of Aggression in Model Systems: The Zebrafish as a New Narrative
Zebrafish (Danio rerio) are rapidly becoming a powerful new model organism for neurobehavioral and neuropharmacological research, including...
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Neuropharmacology of Aggression in Model Systems: The Zebrafish as a New Narrative
Zebrafish (Danio rerio) are rapidly becoming a powerful new model organism for neurobehavioral and neuropharmacological research, including...
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Repeated Behavioral Patterns in Animal Models of Autism
This chapter describes animal models for autism, with a focus on RRBIs. ASD evidently has a robust genetic component, with strong familial...
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The Hole-Board Test in Mutant Mice
First described by Boissier and Simon in (Ther Recreat J 17:1225–1232, 1962), the hole-board has become a recognized test of anxiety and spatial...
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Overexpression of Androgen Receptors Masculinizes 2D:4D Digit Ratios in Mice
Studying the role of the prenatal endocrine environment in humans is challenging due to the ethical and practical considerations of measuring hormone...
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Genetic Analysis of the Stereotypic Phenotype in Peromyscus maniculatus (deer mice)
Peromyscus maniculatus , including the laboratory stock BW, have been used as a model organism for autism spectrum disorder and obsessive–compulsive...
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A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms
We aimed to detect Attention-deficit/hyperactivity (ADHD) risk-conferring genes in adults. In children, ADHD is characterized by age-inappropriate...
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Linking Delay Discounting and Substance Use Disorders: Genotypes and Phenotypes
Research supports the idea that “delay discounting,” also known as temporal discounting, intertemporal choice, or impulsive choice, is a transdisease...
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The Quinpirole Hypolocomotive Effects are Strain and Route of Administration Dependent in SHR and SLA16 Isogenic Rats
The SHR and SLA16 inbred strains present behavioral differences in anxiety/emotionality that could be under the influence of dopaminergic...
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Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression
Physical exercise (PE) and environmental enrichment (EE) have consistently been shown to modulate behavior and neurobiological mechanisms. The...
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Effects of Repeated Treatment with Midazolam in SHR and SLA16 Rat Strains in the Triple Test
We exposed male and female rats of SHR (Spontaneously Hypertensive Rats) and SLA16 (SHR.LEW- Anxrr16 ) strains, in a non-drugged state, for five...
