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Recombinant Inbred Strain

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Encyclopedia of Animal Cognition and Behavior

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Synonym

Recombinant inbred lines

Definition

A recombinant inbred strain is a strain formed by crossing two inbred strain, which is continued to be crossed or say repeated for the next 20 generations.

Introduction

Recombinant inbred strains (RIS) are the offspring developed from the two foremost inbred lines, which contains approximately the same ratio of genetic contributions of their ancestors. The repeated crossing is strictly done between brother x sister to form a new inbred line; this leads to the construction of a genome which is mosaic of the genome of the parents.

In this way production of a line is done which has unique property but is related to one another. It can also be understood as when different parents which were inbred meant as members of a set.

These organisms undergo important recombination events in their chromosomes, which they inherit from more than two inbred lines.

Recombinant inbred strains are produced by combination of selfing progeny of individual members...

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References

  • Adamová, E., Williams, R. W., & Jones, B. C. (2018). The use of recombinant inbred strains in systems genetics and functional analyses in behavioral pharmacology. In Molecular-genetic and statistical techniques for behavioral and neural research (pp. 133–150). London: Elsevier.

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  • Bailey, D. (1981). Recombinant inbred strains and bilineal congenic strains.

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  • Pollard, D. A. (2012). Design and construction of recombinant inbred lines. In Quantitative Trait Loci (QTL) (pp. 31–39). Springer.

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  • Silver, L. (2001). Recombinant inbred strains.

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Author information

Authors and Affiliations

  1. Molecular Biology Division, Bhabha Atomic Research Centre, Mumbai, India

    Dhirendra Kumar Sharma

  2. Life Sciences, Devi Ahilya Vishwawidhalaya, Indore, India

    Arwa Ali

Authors
  1. Dhirendra Kumar Sharma
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  2. Arwa Ali
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Corresponding author

Correspondence to Dhirendra Kumar Sharma .

Editor information

Editors and Affiliations

  1. Oakland University , Rochester, MI, USA

    Jennifer Vonk

  2. Department of Psychology, Oakland University Department of Psychology, Rochester, MI, USA

    Todd Shackelford

Section Editor information

  1. Penn State Worthington Scranton, Scranton, USA

    Douglas Sellers

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Sharma, D.K., Ali, A. (2019). Recombinant Inbred Strain. In: Vonk, J., Shackelford, T. (eds) Encyclopedia of Animal Cognition and Behavior. Springer, Cham. https://doi.org/10.1007/978-3-319-47829-6_544-1

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  • DOI: https://doi.org/10.1007/978-3-319-47829-6_544-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-47829-6

  • Online ISBN: 978-3-319-47829-6

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