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Sclareol: Isolation, Structural Modification, Biosynthesis, and Pharmacological Evaluation – A Review
Sclareol, isolated from a variety of plant species like Salvia sclarea , is a labdane diterpene of high value for the flavour and fragrance...
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Pristimerin: Natural Occurrence, Biosynthesis, Pharmacology, and Pharmacokinetics
Pristimerin is a naturally occurring triterpenoid originally isolated from plant members of the genus Pristimera Miers, Celastraceae, and can be also...
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BIOSYNTHESIS OF PLANT SUBSTANCES; BIOGENETIC RELATIONSHIPS
The bioactive substances in medicinal plants will be discussed on the basis of their chemical structure, or more precisely, of a...
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Recent advances on Pestalotiopsis genus: chemistry, biological activities, structure–activity relationship, and biosynthesis
Strains of the fungal genus Pestalotiopsis are reported as large promising sources of structurally varied biologically active metabolites. Many...
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Biosynthesis and Biological Activities of Carvone and Carvotanacetone Derivatives
The search for new molecules with biochemical and pharmacological efficacy has led scientists to investigate a very wide range of natural or...
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Biosynthesis, Characterization and Antimicrobial Response of Silver Nanoparticles Using an Aqueous Extract of Taraxacum officinale
The world faces a grave threat from antimicrobial resistance. Currently, many bacterial and fungal infections cannot be treated with the majority of...
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Isolation, structure elucidation, total synthesis, and biosynthesis of dermazolium A, an antibacterial imidazolium metabolite of a vaginal bacterium Dermabacter vaginalis
Dermabacter vaginalis is a human-derived bacterium isolated from vaginal fluid of a Korean female in 2016. Although several human-related species in Dermabacter...
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Expression of Genes Involved in the Biosynthesis of Crocin and Safranal in Cell Suspension Culture of Saffron (Crocus sativus)
Saffron possesses important medicinal properties, all of which are due to the secondary metabolites such as crocin, picrocrocin, and safranal. This...
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Beta resorcylic acid lactones (RALs) from fungi: chemistry, biology, and biosynthesis
β -Resorcylic acid lactones (RALs) are one of the major polyketides produced by fungi, and some of them have a diverse array of biological activities....
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Changes in regulators of lipid metabolism in the brain: a study of animal models of depression and hypothyroidism
Metabolic disturbances in the brain are assumed to be early changes involved in the pathogenesis of depression, and these alterations may be...
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Enhanced Bioactive Constituents and Improved AMPK and GLUT Dependent Glucose Uptake Effect of Thunbergia laurifolia Leaves by Calcium Chloride and Yeast Extract Elicitors in Postharvest Treatment
Thunbergia laurifolia Lindl., Acanthaceae, leaves are a well-known commercialized infusion tea for health-supplement proposes. Its major phytochemical...
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Potential biological functions and future perspectives of sialylated milk oligosaccharides
Sialyllactoses (SLs) primarily include sialylated human milk oligosaccharides (HMOs) and bovine milk oligosaccharides (BMOs). First, the safety...
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Resveratrol, Tyrosol and Their Derivatives Inhibit Platelet Activating Factor Biosynthetic Enzymes in Homogenized U-937 Cells
Platelet activating factor (PAF) is a potent lipid mediator involved in inflammation, among other pathophysiological conditions. Bioactive compounds...
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Betulinic Acid Modulates Redox Imbalance and Dysregulated Metabolisms, While Ameliorating Purinergic and Cholinergic Activities in Iron-Induced Neurotoxicity
The neuroprotective properties of betulinic acid were investigated in oxidative-mediated neurotoxicity induced with Fe 2+ in isolated rats’ brains....
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Calixbenoquin: Calixarene-Based Cluster of Monobenzone as a New Anti-Tyrosinase Agent
Tyrosinase, copper-containing glycoprotein, is a key enzyme in the biosynthesis of melanin pigment from L-tyrosine. The excessive production of...
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Does kisspeptin participate in GABA-mediated modulation of GnRH and GnRH receptor biosynthesis in the hypothalamic-pituitary unit of follicular-phase ewes?
BackgroundThe inverse relationship between GnRH transcript level and GABA neurons activity has suggested that GABA at the hypothalamic level may...
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Influence of in vitro micropropagation on lycorine biosynthesis and anticholinesterase activity in Hippeastrum goianum
Hippeastrum goianum (Ravenna) Meerow, Amaryllidaceae, is an endemic species from the Cerrado, Brazil; there are only few studies about its chemistry...
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Friedelin and 3β-Friedelinol: Pharmacological Activities
The interest in herbal medicine as a source of drug leads is being reinforced, especially for tackling challenging therapeutic areas such as...
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Mitochondrial connection to ginsenosides
Mitochondria play an essential role in energy synthesis and supply, thereby maintaining cellular function, survival, and energy homeostasis via...
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PLANT BIOTECHNOLOGY
Extensive research is underway worldwide on the production of active plant components from medicinal plants under controlled, reproducible conditions...