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The Anti-angiogenic and Anti-microbial Effect of Diosmin: Potential Receptor Interactions via Molecular Docking
This study examined the antiangiogenic capacity of diosmin in vitro and their interactions with certain important receptors related to cancer and...
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Physical-Chemical Characterizations of Synthetic Dual Niosomes for Antibacterial Delivery of Lysostaphin and LL-37
Non-ionic surfactant vesicles known as niosomes are synthetic vesicles with numerous pharmaceutical applications. In this study, a unique combination...
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EGF, a veteran of wound healing: highlights on its mode of action, clinical applications with focus on wound treatment, and recent drug delivery strategies
Epidermal growth factor (EGF) has been used in wound management and regenerative medicine since the late 1980s. It has been widely utilized for a...
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P450 Biotechnology
Cytochrome P450s accept a broad spectrum of substrates and catalyze a vast variety of chemical transformations under mild reaction conditions.... -
Nuclear Magnetic Resonance-Based Screening Methods for Drug Discovery
Nuclear magnetic resonance (NMR) techniques are widely used in the drug discovery process. The primary feature exploited in these investigations is... -
Mutant presenilin 2 increases acetylcholinesterase activity in neuronal cells
A presenilin 2 mutation is believed to be involved in the development of Alzheimer's disease. In addition, transgenic mice with a presenilin 2...
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Role of Disulfide Bond of Arylsulfate Sulfotransferase in the Catalytic Activity
Bacterial arylsulfate sulfotransferase (ASST) catalyzes the transfer of sulfate group from a phenyl sulfate ester to a phenolic acceptor. The...
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Antibody Fragments
Monoclonal antibodies have become widely accepted as safe and effective therapeutics in indications as diverse as oncology, inflammation, and... -
Synthesis of macrolide pheromones
This review considers pathways for the synthesis of macrocyclic lactones (macrolides) identified as components of pheromones of insects of the order...
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