Search
Search Results
-
Integrated LC-MS/MS Method and Network Pharmacology for Exploring the Mechanism of Neuroprotective Effect of Ginsenoside Rc in Oxygen-Glucose Deprivation/Reperfusion Injury
Ginsenoside Rc is one of the active components of “nao-mai-tong,” which is a traditional Chinese medicine prescription widely used in the treatment...
-
Analysis of Eleutherosides by Tandem Mass Spectrometry: Possibilities of Standardizing a Multi-Phytoadaptogen Formulation for Preventive Oncology
The major bioactive constituents in extracts from roots of Eleutherococcus senticosus (Rupr. & Maxim) (Araliaceae) and in a multi-adaptogen herbal...
-
Luteolin for neurodegenerative diseases: a review
Neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and multiple sclerosis affect millions of people...
-
Development of a LC-MS/MS Method for the Quantification of Myricitrin: Application to a Pharmacokinetic Study in Rats
A highly sensitive reversed-phase liquid chromatography coupled to tandem mass spectrometry for the quantification of myricitrin in rat plasma was...
-
Secondary Metabolites of Oplopanax elatus: Possibilities for Standardization of a Multiphytoadaptogen for Preventive Oncology
An herbal formulation of a multiphytoadaptogen (MPA) developed at the N. N. Blokhin Cancer Center and containing phytocomponents from Oplopanax elatus ...
-
Mucuna pruriens Seed Extract: a Possible Protective Agent Against Ochratoxin A Neurodegeneration
Mucuna pruriens (L.) DC., Fabaceae, an herbal phytomedicine used in Indian traditional Ayurvedic medicinal concoctions, is known to mediate...
-
Therapeutic Potential of Plantamajoside
Plantamajoside is a phenylpropanoid glycoside that can be extracted from Plantago asiatica L., Plantaginaceae. It is one of the most extensively...
-
Atractylenolides (I, II, and III): a review of their pharmacology and pharmacokinetics
Atractylodes macrocephala Koidz is a widely used as a traditional Chinese medicine. Atractylenolides (-I, -II, and -III) are a class of lactone...
-
Anti-inflammatory Activity of Total Alkaloids in Nelumbo nucifera and Simultaneous Determination of Major Bisbenzylisoquinolines
Plumula nelumbinis , the green embryo of the mature seeds of Nelumbo nucifera Gaertn., Nelumbonaceae, is widely used in traditional Chinese medicine...
-
Determination of orcinol glucoside by LC-MS in Curculigo orchioides and its application to a pharmacokinetic study
This study was designed to explore the pharmacokinetic regularity of the plasma concentration, tissue distribution and excretion of orcinol glucoside...
-
Metabolic and cardiovascular benefits and risks of 4-hydroxy guanabenz hydrochloride: α2-adrenoceptor and trace amine-associated receptor 1 ligand
Backgroundα 2 -adrenoceptor ligands have been investigated as potential therapeutic agents for the treatment of obesity. Our previous studies have...
-
Simultaneous liquid chromatography- tandem mass spectrometry method to quantify epicatechin and procyanidin B2 in rat plasma after oral administration of Trichilia catigua (catuaba) extract and its application to a pharmacokinetic study
Trichilia catigua A. Juss., Meliaceae, known as catuaba in Brazil, is traditionally used for the treatment of stress, sexual impotence and memory...
-
Recent Advances in the Pharmacological Activities of Glycyrrhizin, Glycyrrhetinic Acid, and Their Analogs
In recent years, natural products have become increasingly popular for treating various ailments. Studies have shown that glycyrrhizin and...
-
The potential health benefits of the isoflavone glycoside genistin
Genistin is a type of isoflavone glycoside and has a broad range of health benefits. It is found in a variety of dietary plants, such as soybean,...
-
Medicinal and Therapeutic Properties of Ephedra
Ephedra is one of the oldest medicinal plants in traditional Chinese medicine for nearly 5000 years. The medicinal species are used as a stimulant...
-
Pharmacological properties of specioside from the stem bark of Tabebuia aurea
Iridoids are secondary metabolites with several biological activities. They are often found in species of the genus Tabebuia Gomes ex A.P. de...
-
Simultaneous determination of six bioactive components of total flavonoids of Scorzonera austriaca in rat tissues by LC-MS/MS: application to a tissue distribution study
A liquid chromatography-tandem mass spectrometry method was developed and validated for simultaneous determination of six bioactive constituents...
-
From Relative to Absolute Stereochemistry of Secondary Metabolites: Applications in Plant Chemistry
Structural elucidation of specialized metabolites or natural plant products, especially the stereochemical features of chiral bioactive metabolites,...
-
Structure elucidation of small organic molecules by contemporary computational chemistry methods
Small molecules derived from natural sources such as plants, fungi, bacteria, or synthetic materials have served as promising drug candidates for a...
-
Optimization for extraction of an oil recipe consisting of white pepper, long pepper, cinnamon, saffron, and myrrh by supercritical carbon dioxide and the protective effects against oxygen-glucose deprivation in PC12 cells
This study is to investigate the most efficient extractives of extracting oil recipe for stroke treatment and the protective effects on an oxygen and...