Search
Search Results
-
Gastric cancer and mesenchymal stem cell-derived exosomes: from pro-tumorigenic effects to anti-cancer vehicles
Gastric cancer (GC) is one of the most prevalent malignancies in the world, with a high mortality rate in both women and men. Conventional...
-
The role and application of transcriptional repressors in cancer treatment
Gene expression is modulated through the integration of many regulatory elements and their associated transcription factors (TFs). TFs bind to...
-
Synthesis, Antiproliferative, and Molecular Docking Studies of 3-Mercapto-1,2,4-Triazole Derivatives as Combretastatin A-4 Analogs
In the present work, a series of 1,2,4-triazole derivatives are designed as combretastatin A-4 analogs with the 4-nitrophenyl group and different...
-
Unlocking the Potential of Brusatol as an Antitumoral Agent: Molecular Mechanisms and Therapeutic Benefits
Traditional Chinese medicine relies on brusatol to combat various diseases, including cancer. Considering the wide variety of natural substances and...
-
Galangin, as a Potential Anticancer Agent
Cancer is a major global health issue and one of the main causes of mortality worldwide. In recent years, cancer mortality and morbidity rates have...
-
Viability of Tumor Cells (K562, Hep-2, HeLa) and Rat Fibroblasts in the Presence of Pterostilbene and Extracts of Licorice Root and Andrographis Paniculata
Results from in vitro studies of the effect of pterostilbene, licorice root extract, and Andrographis paniculata extract on the viability of rat...
-
Indirubin-3-monoxime and thymoquinone exhibit synergistic efficacy as therapeutic combination in in-vitro and in-vivo models of Lung cancer
In this study, we report the combination of indirubin-3-monoxime (I3M) and thymoquinone (Tq) to have excellent therapeutic efficacy in models of Lung...
-
Advances in plant-derived natural products for antitumor immunotherapy
In recent years, immunotherapy has emerged as a novel antitumor strategy in addition to traditional surgery, radiotherapy and chemotherapy. It...
-
Comparative study of the binding between chlorogenic acid and four proteins by isothermal titration calorimetry, spectroscopy and docking methods
AbstractAs a polyphenolic compound, chlorogenic acid has antioxidant, anti-inflammatory, antiviral, anti-obesity and other effects. Based on the...
-
Medicinal Ferns of Psilotaceae, Huperziaceae, and Lycopodiaceae
This chapter introduces 8 species of medicinal ferns in 3 families, such as Psilotum nudum of Psilotaceae, Huperzia serrate and Phlegmariurus fordii...
-
BIOLOGICAL ACTIVITY OF COMPOUNDS OF PLANT ORIGIN
Due to their structural diversity and specific biological effects, natural substances play an important role in medication. Many of the medicines...
-
Synthesis of Derivatives of the 2-Arylquinoline Alkaloid Dubamine and their Cytotoxicity
5′-Nitro- ( 2 ) and 5′-aminodubamine ( 3 ) were sequentially synthesized from the alkaloid dubamine. Condensation of 3 with 15 aldehydes gave imines,...
-
Therapeutic Proteins and Advanced Therapy Medicinal Products
This chapter is divided in two parts: Therapeutic proteins and Advanced Therapy Medicinal Products (ATMPs)....
-
Medicinal Angiosperms of Papilionaceae (Cont. I)
This chapter introduces 32 species of medicinal plants in 1 family, mainly including Crotalaria albida, Crotalaria assamica, Crotalaria calycina,...
-
Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third largest family of flowering plants. The genus Sophora comprises...
-
Growth retardation and apoptotic death of tumor cells by Artemisia herba-alba oral administration in Ehrlich solid carcinoma bearing mice
At present, there is a rapidly growing interest in studying the cytotoxic effects of Artemisia herba alba Asso, Asteraceae, in various cancer cell...
-
-
Medicinal Angiosperms of Scrophulariaceae
This chapter introduces 42 species of medicinal plants in 1 family, mainly including Adenosma glutinosum, Adenosma indianum, Bacopa monnieri,...
-
The NK-1 receptor antagonist L-732,138 induces apoptosis in human gastrointestinal cancer cell lines
BackgroundGastric and colon cancer cells express the neurokinin-1 receptor (NK-1R) and the peptide substance P (SP), after binding to this receptor,...
-
Efficacy of adjuvant treatment with nebulized lidocaine in improving clinical and pulmonary function parameters of acute asthma attacks: a randomized double-blind clinical trial
PurposeEfficient novel medications can facilitate the acute phase of asthma treatment. The aim of this study was to investigate whether nebulized...
