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Unraveling the mechanistic interplay of mediators orchestrating the neuroprotective potential of harmine
Neurodegenerative diseases (NDDs) encompass a range of conditions characterized by the specific dysfunction and continual decline of neurons, glial...
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Mechanistic insights on TLR-4 mediated inflammatory pathway in neurodegenerative diseases
Neurodegenerative diseases (NDDs) pose a significant issue in healthcare, needing a thorough knowledge of their complex molecular mechanisms. A...
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Sucrose Diester of Aryldihydronaphthalene-Type Lignan with Anti-inflammatory Activity from Heliotropium angiospermum
A new lignan (3a → 9′:6a → 9-[(7′ S ,8′ R )-4,4′-dihydroxy-3,3′,5,5′-tetramethoxy-2,7′-cycloligna-7-en-9,9′dicarbonyl]-6b-( p -coumaroyl) sucrose) was...
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Anti-inflammatory and Antioxidant Activity of Eugenial D from Eugenia astringens
Eugenia astringens Cambess. (syn. Eugenia umbelliflora O.Berg), Myrtaceae, is a plant widely used in the Brazilian traditional medicine due to its...
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Nanoemulsion Improves the Anti-inflammatory Activity of Carvacrol upon Oral Administration
Carvacrol is the main phenolic monoterpene isolated from the essential oils of plants from the genus Origanum L., Lamiaceae. Carvacrol has several...
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Mechanistic interplay of various mediators involved in mediating the neuroprotective effect of daphnetin
Daphnetin is a 7, 8 dihydroxy coumarin isolated from different medicinal plants of the Thymelaeaceae family and exhibits copious pharmacological...
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New Non-Carboxylic Acid Chalcones as Anti-Inflammatory Agents: Molecular Docking, Synthesis and Admet Studies
Chalcones in combination with heterocyclic moieties have been reported to exhibit diverse biological activities. The present study was aimed to...
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Anti-Inflammatory and Analgesic Activity of Ethanolic Extract of Tubers and Different Fractions of Eulophia nuda Lindl.
Recently, in human and animal diseases, inflammation and pain have become the focus of scientific research as it affects more people than any other...
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Anti-Inflammatory, Wound Healing, and Hepatoprotective Effects of Ethanol Extract of Rice Bran in Rodent Models
Rice bran is an essential co-product in rice meals with many biological activities. This study was aimed at evaluating the anti-inflammatory, wound...
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Implications of inflammatory cell death-PANoptosis in health and disease
Regulated cell death (RCD) pathways, such as pyroptosis, apoptosis, and necroptosis, are essential for maintaining the body’s balance, defending...
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Anti-inflammatory Activity of Total Alkaloids in Nelumbo nucifera and Simultaneous Determination of Major Bisbenzylisoquinolines
Plumula nelumbinis , the green embryo of the mature seeds of Nelumbo nucifera Gaertn., Nelumbonaceae, is widely used in traditional Chinese medicine...
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Chemical Constituents and Anti-inflammatory, Antinociceptive, and Antioxidant Activities of Salvia melissiflora Aerial Parts
Chromatographic fractionation of dichloromethane and ethanol extracts of Salvia melissiflora Benth., Lamiaceae, aerial parts led to the...
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Anti-inflammatory and Antinociceptive Potential of Verbascum latisepalum
Verbascum L. species are mainly used for inflammatory diseases and against malaria in traditional medicine. Therefore, we aimed to assess the in vivo ...
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Evaluation of anti-inflammatory response of berberine-loaded gum nanocomplexes in carrageenan-induced acute paw edema in rats
BackgroundBerberine is a natural plant alkaloid and has been reported to possess anti-inflammatory activity. However, berberine’s poor...
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Topical Anti-inflammatory Effect of Annona muricata (graviola) Seed Oil
Different parts of Annona muricata L., Annonaceae, are widely used for their biological activities. The fruit of this plant, called “graviola,” is...
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Evaluation of the Antioxidant Activity and Anti-Inflammatory Effect of Root Extracts of Astragalus Membranaceus, Scutellaria Baicalensis, and Phlojodicarpus Sibiricus
The goal of the study was to determine quantitatively the content of phenolic compounds in the extract from roots of Astragalus membranaceus , Scutellar...
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Spectroscopical Analysis of Andean Plant Species with Anti-inflammatory, Antioxidant, and Antibacterial Activities
Achyrocline satureioides (Lam.) DC., Asteraceae, Clinopodium bolivianum Kuntze, Lamiaceae, Rubus urticifolius Poir., Rosaceae, and Tagetes elliptica ...
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Anti-inflammatory Response and Detection of Pharmacologically Active Components in Serum of Rats with Carrageenan-Induced Paw Swelling Treated with Phellodendron chinense
Phellodendron chinense C.K.Schneid., Rutaceae, is a traditional Chinese medicine that is considered to have heat-clearing and detoxifying actions and...
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Renal tubular PAR2 promotes interstitial fibrosis by increasing inflammatory responses and EMT process
Renal fibrosis is defined by excessive extracellular matrix (ECM) accumulation and is associated with a decreased kidney function. Increased...
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Berberine and its derivatives represent as the promising therapeutic agents for inflammatory disorders
Berberine, with the skeleton of quaternary ammonium, has been considered as the well-defined natural product in treating multiple diseases, including...
