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Phytochemistry and pharmacological activity of the genus artemisia
Artemisia and its allied species have been employed for conventional medicine in the Northern temperate regions of North America, Europe, and Asia...
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GC-MS Bioactives Profiling, Antibacterial and Cytotoxic Potential of Jamun (Syzygium cumini L.) Extracts Against Food-Borne Pathogen Salmonella enteritidis
Salmonellosis is a major food-borne disease in humans worldwide caused by Salmonella enteritidis . Currently, selected phytochemicals are gaining...
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Capillarisin Pretreatment Inhibits Oxidative Stress and Inflammation in Rats After Myocardial Infarction Induction
Myocardial infarction is a type of cardiovascular disease that leads to the loss of cardiomyocyte and cardiac dysfunction and is classified as the...
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Six Phthalides as Potent Modulators of the Blood Tumor Barrier Increase the Transmembrane Transport of Compatible Compounds Via Transcellular and Paracellular Pathways
The treatment of brain tumors is greatly limited due to the presence of the blood tumor barrier (BTB). Our previous research has shown that the...
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Standardization of a Formulation of Timogar and Ferula Assa-Foetida Dry Resin Extract and its Biological Activity
A dry extract of Ferula assa-foetida L. gum-resin was obtained. A formulation was developed on the basis of the extract and timogar preparation....
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Bruceine D Sensitizes Human Ovarian Cancer Cells to Paclitaxel Through JNK and STAT3 Signal Regulation
Exploring novel regimens is essential to ensure the efficacy of paclitaxel-based chemotherapy in epithelial ovarian cancer. Brucea javanica (L.)...
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A Systematic Review on Chemical Actives from Plant Sources, Targets and Chemotherapy for Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) accounts for 15 – 20% of all other types of cancer. Due to the lack of target-specific compounds against...
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Hyperoside attenuates pyrrolizidine alkaloids-induced liver injury by ameliorating TFEB-mediated mitochondrial dysfunction
Pyrrolizidine alkaloids (PAs) are potent hepatotoxins that can cause liver damage. Hyperoside (Hyp), a natural flavonoid, can be extracted from...
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A Systematic Review of Pharmacovigilance Systems in Develo** Countries Using the WHO Pharmacovigilance Indicators
BackgroundIn the context of the growth of pharmacovigilance (PV) among develo** countries, this systematic review aims to synthesise current...
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Isolation and identification of Anti-Oxidant Fraction from Active Extract of Rhizophora mucronata Poir. Leaves
Rhizophora mucronata Poir is widely used in traditional medicine for treatment of various diseases including cancer. Different solvent extracts...
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A Novel Caffeoylquinic Acid from Lonicera japonica Exerts Cytotoxic Activity by Blocking the YAP-CTGF Signaling Pathway in Hepatocellular Carcinoma
We have purified a novel caffeoylquinic acid named 3,4-di- O -caffeoylquinic acid isobutyl ester from the flower buds of Lonicera japonica Thunb.,...
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Friedelin and 3β-Friedelinol: Pharmacological Activities
The interest in herbal medicine as a source of drug leads is being reinforced, especially for tackling challenging therapeutic areas such as...
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Neurological disorders of COVID-19: insights to applications of natural products from plants and microorganisms
In addition to the typical respiratory manifestations, various disorders including involvement of the nerve system have been detected in COVID-19...
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Structures, biomimetic synthesis, and anti-SARS-CoV-2 activity of two pairs of enantiomeric phenylpropanoid-conjugated protoberberine alkaloids from the rhizomes of Corydalis decumbens
(±)-Decumicorine A ( 1 ) and (±)- epi -decumicorine A ( 2 ), two pairs of enantiomeric isoquinoline alkaloids featuring a novel phenylpropanoid-conjugated...
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Pharmacy Services in the Time of Pandemic
Pandemics have a devastating impact on the health care system and society from health, social, and economic perspectives. Pharmacists play a key role...
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Flavonoids from Siparuna cristata as Potential Inhibitors of SARS-CoV-2 Replication
The novel coronavirus SARS-CoV-2 has been affecting the world, causing severe pneumonia and acute respiratory syndrome, leading people to death....
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UPLC-Q-Orbitrap HRMS Analysis of Coptis chinensis Aerial Parts and Its Regulatory Activity on Glucose-lipid Metabolism
Coptis chinensis Franch., Ranunculaceae, is a widely used herbal medicine in Asian countries. It exhibits many important pharmacological effects. The...
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Recent Advances in the Pharmacological Activities of Glycyrrhizin, Glycyrrhetinic Acid, and Their Analogs
In recent years, natural products have become increasingly popular for treating various ailments. Studies have shown that glycyrrhizin and...
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Physicochemical and Bioassay Directed GC-MS Analyses of Chloroform Extract of Pteris cretica L.
This study was aimed to explore the potential of Pteris cretica L. to be used as herbal remedy. The P. cretica dried plant powder was subjected to a...
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Identification of Plastrum Testudinis used in traditional medicine with DNA mini-barcodes
The carapace of the tortoise Chinemys reevesii is an ingredient of “Guijia”, a traditional Chinese medicine. However, C. reevesii is difficult to...