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Biopharmaceutics
Biopharmaceutics, in connection with pharmacokinetics, is the field that investigates and describes everything that happens with a medicinal product... -
Pharmacological Activities and Pharmacokinetics of Glycycoumarin
Glycycoumarin is a representative coumarin compound with significant pharmacological activities isolated from Glycyrrhiza uralensis Fisch., Fabaceae....
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Revisiting Ipriflavone: a Potential Isoflavone for the Management of Postmenopausal Osteoporosis
Ipriflavone is a nutraceutical extensively used in Asian countries since 1890 for postmenopausal osteoporosis as a phytoestrogen to inhibit bone...
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Knowledge-Based Design of Multifunctional Polymeric Nanoparticles
Conventional drug delivery systems (DDS) today still face several drawbacks and obstacles. High total doses of active pharmaceutical ingredients... -
Production and therapeutic use of astaxanthin in the nanotechnology era
AbstractAstaxanthin (AXT) is a red fat-soluble pigment found naturally in aquatic animals, plants, and various microorganisms and can be manufactured...
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Using Polysorbates to Create Parenteral Dosage Forms of Hydrophobic Substances (A Review)
Low solubility of drugs is a constantly encountered problem for pharmaceutical science in the field of parenteral dosage form development. This...
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Inclusion Complex of Hydroxypropyl-β-Cyclodextrin with Carbamazepine: Preparation by Co-Dissolution, Characterization, and In Vivo Comparative Study of the Anticonvulsant Activity
The inclusion complex of the antiepileptic drug carbamazepine with hydroxypropyl-β-cyclodextrin was prepared by co-dissolution in practically...
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Potential of Nanoencapsulated Quercetin Topical Formulations in the Management of Diabetic Foot Ulcer
Diabetic foot ulcer originates due to peripheral neuropathy, immunosuppression, resistance to infections, and peripheral arterial disease. The...
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Formulating GML-1 Tablets Using the Harrington Desirability Function
Features of using the generalized Harrington desirability function for the selection of a binder and lubricant for GML-1 ( N -benzyl- N -methyl-1-phenylpyrrolo[1,2-...
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Enhanced bioavailability and hepatoprotective effect of silymarin by preparing silymarin-loaded solid dispersion formulation using freeze-drying method
This study aimed to develop a solid dispersion formulation of silymarin (Silymarin-SD) using freeze-drying method to enhance its oral bioavailability...
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The Potential Clinical Uses and Nanoformulation Strategies of Kaempferol, a Dietary Flavonoid
This review aims to provide a brief introduction to kaempferol with respect to its various therapeutic properties such as anticancer, antioxidant,...
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Eye
In this chapter several aspects of ocular dosage forms are discussed with emphasis on eye drops, eye lotions and eye ointments prepared in... -
Physicochemical and Biopharmaceutical Studies of Solid Dispersions of Cinnarizine
Cinnarizine is an economically affordable drug that belongs to the calcium-channel blocker group and is widely used to treat cerebral diseases. It is...
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Scaling-Up of Solid Orals: Granulation, Drying, Size Reduction, Blending, Compression, and Coating Technologies
The scaling-up is a crucial step in the development and manufacturing process. The goal is to optimize the process to ensure consistent and efficient... -
Solid Dispersions of Medamine and Albendazole with Water-Soluble Polymers: Preparation and Properties
Solid dispersions of medamine and albendazole with water-soluble polymers (PVP, arabinogalactan) were obtained by mechanochemical technology to...
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Solubility and Stability of Proroxan at Various PH Values
The solubility and stability of the nonselective α-adrenoblocker 1-(2,3-dihydro-1,4-benzdioxin-6-yl)-3-(3-phenyl-1-pyrrolidinyl)-1-propanone...
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New Water-Soluble IR Photosensitizer in the Bacteriochlorophyll a Series
Chlorin and bacteriochlorin derivatives are at present the most promising compounds used in photodynamic therapy. However, the use of these...
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Effect of Solid Dispersions with Polyethylene Glycol 1500 on the Solubility of Indomethacin
Solid dispersions (SDs) of indomethacin with polyethylene glycol 1500 (PEG-1500) were studied to determine their effect on indomethacin solubility....
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Standardization of a Formulation of Timogar and Ferula Assa-Foetida Dry Resin Extract and its Biological Activity
A dry extract of Ferula assa-foetida L. gum-resin was obtained. A formulation was developed on the basis of the extract and timogar preparation....
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Calixbas: Calix[4]Arene-Based Bioactive Bolaamphiphiles
The present short review covers a new class of bioactive fully functionalized calix[4]arenes representing symmetrical bolaform amphiphiles associated...