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  1. Prediction model for drug response of acute myeloid leukemia patients

    Despite some encouraging successes, predicting the therapy response of acute myeloid leukemia (AML) patients remains highly challenging due to tumor...

    Quang Thinh Trac, Yudi Pawitan, ... Trung Nghia Vu in npj Precision Oncology
    Article Open access 24 March 2023
  2. Artificial intelligence models in prediction of response to cardiac resynchronization therapy: a systematic review

    The aim of the presented review is to summarize the literature data on the accuracy and clinical applicability of artificial intelligence (AI) models...

    Wojciech Nazar, Stanisław Szymanowicz, ... Ludmiła Daniłowicz-Szymanowicz in Heart Failure Reviews
    Article Open access 20 October 2023
  3. Prediction model for treatment response of primary membranous nephropathy with nephrotic syndrome

    Objective

    To investigate the predictors and establish a nomogram model for the prediction of the response to treatment in primary membranous...

    Min Li, **aoying Lai, ... Xuemei Liu in Clinical and Experimental Nephrology
    Article 06 May 2024
  4. AI-assisted prediction of differential response to antidepressant classes using electronic health records

    Antidepressant selection is largely a trial-and-error process. We used electronic health record (EHR) data and artificial intelligence (AI) to...

    Yi-han Sheu, Colin Magdamo, ... Jordan W. Smoller in npj Digital Medicine
    Article Open access 26 April 2023
  5. Immune micro-environment analysis and establishment of response prediction model for PD-1 blockade immunotherapy in glioblastoma based on transcriptome deconvolution

    Purpose

    Only a small proportion of patients obtain survival benefit from PD-1 blockade immunotherapy due to the highly heterogeneous and suppressed...

    Article 05 July 2023
  6. Prediction of response to promising first-line chemotherapy in ovarian cancer patients with residual peritoneal tumors: practical biomarkers and robust multiplex models

    Background

    Platinum/taxane (TC) chemotherapy with debulking surgery stays the mainstay of the treatment in ovarian cancer patients with peritoneal...

    Reika Kawabata-Iwakawa, Norihiro Iwasa, ... Masahiko Nishiyama in International Journal of Clinical Oncology
    Article 20 May 2024
  7. Prediction of TKI response in EGFR-mutant lung cancer patients-derived organoids using malignant pleural effusion

    Patient-derived organoids (PDOs) are valuable in predicting response to cancer therapy. PDOs are ideal models for precision oncologists. However,...

    Sang-Hyun Lee, Kyuhwan Kim, ... Seung Joon Kim in npj Precision Oncology
    Article Open access 21 May 2024
  8. An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study

    The classification of extramural vascular invasion status using baseline magnetic resonance imaging in rectal cancer has gained significant attention...

    Lishan Cai, Doenja M. J. Lambregts, ... Sean Benson in npj Precision Oncology
    Article Open access 22 January 2024
  9. Development and validation of a radiomics-based prediction pipeline for the response to stereotactic radiosurgery therapy in brain metastases

    Objectives

    The first treatment strategy for brain metastases (BM) plays a pivotal role in the prognosis of patients. Among all strategies,...

    Peng Du, **ao Liu, ... Daoying Geng in European Radiology
    Article 28 July 2023
  10. A CAR-T response prediction model for r/r B-NHL patients based on a T cell subset nomogram

    Background

    Chimeric antigen receptor (CAR) T cells for refractory or relapsed (r/r) B cell no-Hodgkin lymphoma (NHL) patients have shown promising...

    **aomei Zhang, Rui Sun, ... Mingfeng Zhao in Cancer Immunology, Immunotherapy
    Article Open access 27 January 2024
  11. Emerging glyco-risk prediction model to forecast response to immune checkpoint inhibitors in colorectal cancer

    Background

    Aberrant glycosylation is one of the most common post-translational modifications leading to heterogeneity in colorectal cancer (CRC). This...

    Peishan Qiu, **aoyu Chen, ... Qiu Zhao in Journal of Cancer Research and Clinical Oncology
    Article 09 February 2023
  12. CT-based radiomics prediction of complete response after stereotactic body radiation therapy for patients with lung metastases

    Purpose

    Stereotactic body radiotherapy (SBRT) is a key treatment modality for lung cancer patients. This study aims to develop a machine...

    Savino Cilla, Domenico Pistilli, ... Francesco Deodato in Strahlentherapie und Onkologie
    Article 31 May 2023
  13. Prediction model of no-response before the first transarterial chemoembolization for hepatocellular carcinoma: TACF score

    Previous clinic models for patients with hepatocellular carcinoma (HCC) receiving transarterial chemoembolization (TACE) mainly focused on the...

    Jia-Wei Zhong, Dan-Dan Nie, ... Si-Hai Chen in Discover Oncology
    Article Open access 17 October 2023
  14. Prediction of locally advanced rectal cancer response to neoadjuvant chemoradiation therapy using volumetric multiparametric MRI-based radiomics

    Purpose

    To assess the role of pretreatment multiparametric (mp)MRI-based radiomic features in predicting pathologic complete response (pCR) of locally...

    Maria El Homsi, Octavia Bane, ... Bachir Taouli in Abdominal Radiology
    Article 27 December 2023
  15. Systemic Inflammation Response Index and Systemic Immune-inflammation Index for Prediction of Pregnancy Loss: a Case–control Study

    The systemic inflammation response index (SIRI) and systemic immune inflammation index (SII) have recently been investigated as new prognostic...

    Zahid Agaoglu, Atakan Tanacan, ... Dilek Sahin in Reproductive Sciences
    Article 04 March 2024
  16. Histopathology images-based deep learning prediction of prognosis and therapeutic response in small cell lung cancer

    Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer characterized by rapid tumor growth and early metastasis. Accurate...

    Yibo Zhang, Zijian Yang, ... Meng Zhou in npj Digital Medicine
    Article Open access 18 January 2024
  17. Baseline [18F]FDG PET/CT and MRI first-order breast tumor features do not improve pathological complete response prediction to neoadjuvant chemotherapy

    Purpose

    To verify the ability of pretreatment [ 18 F]FDG PET/CT and T1-weighed dynamic contrast-enhanced MRI to predict pathological complete response...

    Carla Oliveira, Francisco Oliveira, ... Durval C. Costa in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 26 June 2024
  18. Assessment of treatment response to dendritic cell vaccine in patients with glioblastoma using a multiparametric MRI-based prediction model

    Purpose

    Autologous tumor lysate-loaded dendritic cell vaccine (DCVax-L) is a promising treatment modality for glioblastomas. The purpose of this study...

    Laiz Laura de Godoy, Sanjeev Chawla, ... Suyash Mohan in Journal of Neuro-Oncology
    Article 02 May 2023
  19. Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis

    Background

    Choosing the appropriate antipsychotic drug (APD) treatment for patients with schizophrenia (SCZ) can be challenging, as the treatment...

    Liang-Kun Guo, Yi Su, ... Wei-Hua Yue in Military Medical Research
    Article Open access 02 June 2023
  20. Pediatric diffuse intrinsic pontine glioma radiotherapy response prediction: MRI morphology and T2 intensity-based quantitative analyses

    Objectives

    An easy-to-implement MRI model for predicting partial response (PR) postradiotherapy for diffuse intrinsic pontine glioma (DIPG) is...

    **aojun Yu, Shaoqun Li, ... Linbo Cai in European Radiology
    Article Open access 21 June 2024
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