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Diagnostic value of plasma-derived exosomal miR-223 for epithelial ovarian cancer
ObjectivesTo evaluate the diagnostic value of plasma exosomal miR-223 and its combination with CA125 for the diagnosis of early-stage epithelial...
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LncRNA MAGI2-AS3 promotes fracture healing through downregulation of miR-223-3p
BackgroundLong non-coding RNAs (LncRNAs) are recognized as a pivotal element in the processes of fracture healing and the osteogenic differentiation...
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Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression
There is a strong medical need to develop suitable biomarkers to improve the diagnosis and treatment of depression, particularly in predicting...
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MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands
Bovine mastitis, the most prevalent and costly disease in dairy cows worldwide, decreases milk quality and quantity, and increases cow culling....
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Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis
BackgroundSevoflurane is considered as a lung-protective factor in acute lung injury (ALI), but the underlying molecular mechanism remains largely...
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miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death
BackgroundSudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy...
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MiR-223 plays a protecting role in neutrophilic asthmatic mice through the inhibition of NLRP3 inflammasome
BackgroundNeutrophilic subtype asthma occurs in approximately 15–25% of the asthma cases and is associated with severe airflow obstruction,...
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MicroRNA-223-3p downregulates the inflammatory response in preeclampsia placenta via targeting NLRP3
ObjectiveTo investigate the regulatory role of miR-223-3p in the inflammatory response of PE placenta.
MethodsPE and normal placental tissues were...
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Ovarian Stimulation Altered Uterine Fluid Extracellular Vesicles miRNA Affecting Implantation in Rats
Uterine fluid (UF) extracellular vesicle (EV) miRNA may affect implantation and could be the potential biomarker of endometrial receptivity (ER)....
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Identification of novel circulating miRNAs biomarkers for healthy obese and lean children
BackgroundThe prevalence of childhood obesity and overweight has risen globally, leading to increased rates of metabolic disorders. Various factors,...
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microRNA-223 and microRNA-126 are clinical indicators for predicting the plaque stability in carotid atherosclerosis patients
Studies have demonstrated the essential functions of microRNAs (miRNAs) in cardiovascular disease. Herein, we explored the roles of miR-126 and...
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Clinical and prognostic significance of baseline microRNA 223 in acute ischemic stroke
BackgroundAcute ischemic stroke (AIS) is the second leading cause of disability and death worldwide. Micro-RNA (miRNA)-223 was first identified as a...
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Circulating microRNAs (miR-126, miR-197, and miR-223) are associated with chronic kidney disease among elderly survivors of the Great East Japan Earthquake
BackgroundA recent study has reported that incidence of chronic kidney disease (CKD) is higher in evacuees, but the molecular mechanism still remains...
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MicroRNA-223-3p levels in serum-derived extracellular vesicles predict regression of M2BPGi-based liver fibrosis after hepatitis C virus eradication by direct-acting antiviral agents
BackgroundWe retrospectively investigated microRNA (miRNA) levels in serum-derived extracellular vesicles (EVs) as predictive indicators for...
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Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer
BackgroundGynecologic cancers comprise malignancies in the female reproductive organs. Ovarian cancer ranks sixth in terms of incidence rates while...
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miRNA-223-3p regulates ECT2 to promote proliferation, invasion, and metastasis of gastric cancer through the Wnt/β-catenin signaling pathway
PurposeExpression of the guanine nucleotide exchange factor epithelial cell transforming 2 (ECT2) is elevated in gastric cancer (GC) but its...
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Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway
BackgroundDiabetic cardiomyopathy (DCM) stands as the primary cause of heart failure and mortality among patients with diabetes. Nevertheless,...
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Circular RNA circ-BNC2 (hsa_circ_0008732) inhibits the progression of ovarian cancer through microRNA-223-3p/ FBXW7 axis
BackgroundCircular RNAs (circRNAs) are reported to be key regulators in the progression of human cancers. This work focuses on the function and...
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Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential
BackgroundCirculating MicroRNAs (miRNAs) carried by microvesicles (MVs) have various physiological and pathological functions by post-transcriptional...
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A systematic review and meta-analysis of circulating serum and plasma microRNAs in TB diagnosis
BackgroundTuberculosis (TB) ranks as the second leading cause of death globally among all infectious diseases. This problem is likely due to the lack...
