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Sleep deprivation prevents counterregulatory adaptation to recurrent hypoglycaemia
Aims/hypothesisAttenuated counterregulation after recurrent hypoglycaemia is a major complication of diabetes treatment. As there is previous...
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Hypoglycaemia in type 1 diabetes mellitus: risks and practical prevention strategies
Hypoglycaemia, which occurs when blood levels of glucose fall below what is considered a normal range, is a well-known complication of insulin...
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Glucose metabolism after bariatric surgery: implications for T2DM remission and hypoglycaemia
Although promising therapeutics are in the pipeline, bariatric surgery (also known as metabolic surgery) remains our most effective strategy for the...
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Not only for caregivers: intranasal glucagon for severe hypoglycaemia in a simulation study
AimsTo evaluate: (i) the propensity of paediatrics and emergency medicine residents to select different therapeutic options and (ii) the speed and...
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Hypoglycaemia frequency and physiological response after double or triple doses of once-weekly insulin icodec vs once-daily insulin glargine U100 in type 2 diabetes: a randomised crossover trial
Aims/hypothesisThis study compared the frequency of hypoglycaemia, time to hypoglycaemia and recovery from hypoglycaemia after double or triple doses...
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Pen-administered low-dose dasiglucagon vs usual care for prevention and treatment of non-severe hypoglycaemia in people with type 1 diabetes during free-living conditions: a Phase II, randomised, open-label, two-period crossover trial
Aims/hypothesisConsumption of excess carbohydrates to manage hypoglycaemia can lead to rebound hyperglycaemia and promote weight gain. The objective...
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Minimising hypoglycaemia in the real world: the challenge of insulin
Insulin therapy has been a life saver for people with type 1 diabetes and has been an essential tool in the therapy of people with...
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Effects of continuous glucose monitor-recorded nocturnal hypoglycaemia on quality of life and mood during daily life in type 1 diabetes
Aims/hypothesisThe aim of this work was to assess the effect of spontaneous nocturnal hypoglycaemia on quality of life and mood during subsequent...
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Hypoglycaemia in older home-dwelling people with diabetes- a sco** review
BackgroundHypoglycaemia is associated with cognitive and functional decline in older people with diabetes. Identification of individuals at risk and...
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A Comparison of Validated Methods Used to Assess Impaired Awareness of Hypoglycaemia in Type 1 Diabetes: An Observational Study
IntroductionClarke, Gold and Pedersen are validated methods to assess awareness of hypoglycaemia. Identifying impaired awareness of hypoglycaemia...
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Metabolic control and hypoglycaemia in people with type 1 diabetes: insulin pump therapy vs. intensified insulin therapy in an unselected cohort in routine care
AimsThe aim of this study was to compare individuals with type 1 diabetes with continuous subcutaneous insulin infusion (CSII) and intensified...
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Factors associated with favourable 5 year outcomes in islet transplant alone recipients with type 1 diabetes complicated by severe hypoglycaemia in the Collaborative Islet Transplant Registry
Aims/hypothesisIslet transplantation has been studied in small cohorts of recipients with type 1 diabetes complicated by severe hypoglycaemic events...
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Clinical impact of an integrated e-health system for diabetes self-management support and shared decision making (POWER2DM): a randomised controlled trial
Aims/hypothesisThere is a lack of e-health systems that integrate the complex variety of aspects relevant for diabetes self-management. We developed...
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Analysis Estimating the Potential Cost Impact of Utilizing Flash Glucose Monitoring with Optional Alarms in Swedish Adults with Diabetes with Impaired Awareness of Hypoglycaemia, Using Intensive Insulin
IntroductionThe objective of this analysis was to estimate the costs associated with using flash glucose monitoring with optional alarms as a...
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Management of glucose profile throughout strict COVID-19 lockdown by patients with type 1 diabetes prone to hypoglycaemia using sensor-augmented pump
AimsSpain has been one of the worst affected countries by the COVID-19 pandemic. A very strict lockdown at home was imposed with a tough restriction...
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Metabolic effect of adrenaline infusion in people with type 1 diabetes and healthy individuals
Aims/hypothesisAs a result of early loss of the glucagon response, adrenaline is the primary counter-regulatory hormone in type 1 diabetes....
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Incretins beyond type 2 diabetes
Incretin-based therapies, in particular glucagon-like peptide-1 (GLP-1) receptor agonists, have been evaluated in other forms of diabetes, but...
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Addendum 1: Forum for Injection Technique and Therapy Expert Recommendations, India
With the emerging complexities in chronic diseases and people’s lifestyles, healthcare professionals (HCPs) need to update their methods to manage...
