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Pulling the trigger: Noncoding RNAs in white adipose tissue browning
White adipose tissue (WAT) serves as the primary site for energy storage and endocrine regulation in mammals, while brown adipose tissue (BAT) is...
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White adipose tissue mitochondrial bioenergetics in metabolic diseases
White adipose tissue (WAT) is an important endocrine organ that regulates systemic energy metabolism. In metabolically unhealthy obesity, adipocytes...
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An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy...
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Subcutaneously transplanted xenogeneic protein recruits treg cells and M2 macrophages to induce browning of inguinal white adipose tissue
ObjectiveTo study whether subcutaneously embedding xenogeneic protein threads or synthetic polymer absorbable threads can improve obesity phenotypes...
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The Different Shades of Thermogenic Adipose Tissue
Purpose of ReviewBy providing a concise overview of adipose tissue types, elucidating the regulation of adipose thermogenic capacity in both...
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Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and...
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Obesity and prostate cancer — microenvironmental roles of adipose tissue
Obesity is known to have important roles in driving prostate cancer aggressiveness and increased mortality. Multiple mechanisms have been postulated...
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Gut microbiota in overweight and obesity: crosstalk with adipose tissue
Overweight and obesity are characterized by excessive fat mass accumulation produced when energy intake exceeds energy expenditure. One plausible way...
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Macrophage and T cell networks in adipose tissue
The signals and structure of the tissues in which leukocytes reside critically mould leukocyte function and development and have challenged our...
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Abdominal adipose tissue and type 2 diabetic kidney disease: adipose radiology assessment, impact, and mechanisms
AbstractDiabetic kidney disease (DKD) is a significant healthcare burden worldwide that substantially increases the risk of kidney failure and...
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Asprosin contributes to pathogenesis of obesity by adipocyte mitophagy induction to inhibit white adipose browning in mice
BackgroundAsprosin (ASP) is a newly discovered adipokine secreted by white adipose tissue (WAT), which can regulate the homeostasis of glucose and...
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Intermuscular adipose tissue in metabolic disease
Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as a ‘fatty replacement’ or ‘muscle fat infiltration’ that...
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Immune cells in adipose tissue microenvironment under physiological and obese conditions
PurposeThis review will focus on the immune cells in adipose tissue microenvironment and their regulatory roles in metabolic homeostasis of adipose...
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Role of IL-18 in adipose tissue remodeling and metabolic dysfunction
Background/objectivesProinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects...
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Unraveling the complex roles of macrophages in obese adipose tissue: an overview
Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable plasticity and play pivotal roles in coordinating immune responses...
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Adipose Tissue Plasticity and Insulin Signaling in the Pathogenesis of Type 2 Diabetes
Obesity is a major cause of various metabolic disorders, including type 2 diabetes, nonalcoholic fatty liver disease (NAFLD) and cardiovascular...
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The Role of Adipose Tissue-derived Exosomes in Chronic Metabolic Disorders
Excessive fat deposition in obese subjects promotes the occurrence of metabolic diseases, such as type 2 diabetes mellitus (T2DM), cardiovascular...
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Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases
With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide....
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Adipose tissue composition determines its computed tomography radiodensity
ObjectivesAdipose tissue radiodensity in computed tomography (CT) performed before surgeries can predict surgical difficulty. Despite its clinical...
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Liraglutide induced browning of visceral white adipose through regulation of miRNAs in high-fat-diet-induced obese mice
ObjectiveObesity is characterized by excessive accumulation of white adipose tissue (WAT). Conversely, brown adipose tissue is protective against...