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  1. Pulling the trigger: Noncoding RNAs in white adipose tissue browning

    White adipose tissue (WAT) serves as the primary site for energy storage and endocrine regulation in mammals, while brown adipose tissue (BAT) is...

    Article 29 December 2023
  2. White adipose tissue mitochondrial bioenergetics in metabolic diseases

    White adipose tissue (WAT) is an important endocrine organ that regulates systemic energy metabolism. In metabolically unhealthy obesity, adipocytes...

    Rugivan Sabaratnam, Didde Riisager Hansen, Per Svenningsen in Reviews in Endocrine and Metabolic Disorders
    Article 10 August 2023
  3. An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications

    Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy...

    Zeinab Ghesmati, Mohsen Rashid, ... Masoud Darabi in Reviews in Endocrine and Metabolic Disorders
    Article Open access 05 December 2023
  4. Subcutaneously transplanted xenogeneic protein recruits treg cells and M2 macrophages to induce browning of inguinal white adipose tissue

    Objective

    To study whether subcutaneously embedding xenogeneic protein threads or synthetic polymer absorbable threads can improve obesity phenotypes...

    Shenglu Jiang, Lili Zhu, ... Zhenxiong Zhao in Endocrine
    Article 20 June 2024
  5. The Different Shades of Thermogenic Adipose Tissue

    Purpose of Review

    By providing a concise overview of adipose tissue types, elucidating the regulation of adipose thermogenic capacity in both...

    Yunwen Hu, Yijie Huang, ... Ben He in Current Obesity Reports
    Article 12 April 2024
  6. Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases

    Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and...

    Sabrina Azevedo Machado, Gabriel Pasquarelli-do-Nascimento, ... Kelly Grace Magalhães in Nutrition & Metabolism
    Article Open access 06 September 2022
  7. Obesity and prostate cancer — microenvironmental roles of adipose tissue

    Obesity is known to have important roles in driving prostate cancer aggressiveness and increased mortality. Multiple mechanisms have been postulated...

    Achinto Saha, Mikhail G. Kolonin, John DiGiovanni in Nature Reviews Urology
    Article 17 May 2023
  8. Gut microbiota in overweight and obesity: crosstalk with adipose tissue

    Overweight and obesity are characterized by excessive fat mass accumulation produced when energy intake exceeds energy expenditure. One plausible way...

    Patrice D. Cani, Matthias Van Hul in Nature Reviews Gastroenterology & Hepatology
    Article 08 December 2023
  9. Macrophage and T cell networks in adipose tissue

    The signals and structure of the tissues in which leukocytes reside critically mould leukocyte function and development and have challenged our...

    Ramiah D. Jacks, Carey N. Lumeng in Nature Reviews Endocrinology
    Article 23 October 2023
  10. Abdominal adipose tissue and type 2 diabetic kidney disease: adipose radiology assessment, impact, and mechanisms

    Abstract

    Diabetic kidney disease (DKD) is a significant healthcare burden worldwide that substantially increases the risk of kidney failure and...

    Fei Lu, **lei Fan, ... Dexin Yu in Abdominal Radiology
    Article 17 October 2023
  11. Asprosin contributes to pathogenesis of obesity by adipocyte mitophagy induction to inhibit white adipose browning in mice

    Background

    Asprosin (ASP) is a newly discovered adipokine secreted by white adipose tissue (WAT), which can regulate the homeostasis of glucose and...

    Sheng Chen, Wanwan Yuan, ... Qiren Huang in International Journal of Obesity
    Article 19 February 2024
  12. Intermuscular adipose tissue in metabolic disease

    Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as a ‘fatty replacement’ or ‘muscle fat infiltration’ that...

    Bret H. Goodpaster, Bryan C. Bergman, ... Lauren M. Sparks in Nature Reviews Endocrinology
    Article 23 December 2022
  13. Immune cells in adipose tissue microenvironment under physiological and obese conditions

    Purpose

    This review will focus on the immune cells in adipose tissue microenvironment and their regulatory roles in metabolic homeostasis of adipose...

    Yuchen Jiang, Fengying Gong in Endocrine
    Article 28 September 2023
  14. Role of IL-18 in adipose tissue remodeling and metabolic dysfunction

    Background/objectives

    Proinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects...

    Jaqueline Pereira Lana, Marina Chaves de Oliveira, ... Adaliene Versiani Matos Ferreira in International Journal of Obesity
    Article 08 March 2024
  15. Unraveling the complex roles of macrophages in obese adipose tissue: an overview

    Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable plasticity and play pivotal roles in coordinating immune responses...

    Chang Peng, Jun Chen, ... Jia Li in Frontiers of Medicine
    Article 02 January 2024
  16. Adipose Tissue Plasticity and Insulin Signaling in the Pathogenesis of Type 2 Diabetes

    Obesity is a major cause of various metabolic disorders, including type 2 diabetes, nonalcoholic fatty liver disease (NAFLD) and cardiovascular...

    Masaji Sakaguchi in Diabetology International
    Article 18 December 2023
  17. The Role of Adipose Tissue-derived Exosomes in Chronic Metabolic Disorders

    Excessive fat deposition in obese subjects promotes the occurrence of metabolic diseases, such as type 2 diabetes mellitus (T2DM), cardiovascular...

    Rui He, Yong Chen in Current Medical Science
    Article 20 June 2024
  18. Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases

    With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide....

    Wenxi Fang, Saiyang **e, Wei Deng in Journal of Cardiovascular Translational Research
    Article 17 October 2023
  19. Adipose tissue composition determines its computed tomography radiodensity

    Objectives

    Adipose tissue radiodensity in computed tomography (CT) performed before surgeries can predict surgical difficulty. Despite its clinical...

    Amani Zoabi, Einav Bentov-Arava, ... Katherine Margulis in European Radiology
    Article 01 September 2023
  20. Liraglutide induced browning of visceral white adipose through regulation of miRNAs in high-fat-diet-induced obese mice

    Objective

    Obesity is characterized by excessive accumulation of white adipose tissue (WAT). Conversely, brown adipose tissue is protective against...

    Li Zhao, Wenxin Li, ... Guoyue Yuan in Endocrine
    Article 20 February 2024
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