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  1. Biomarkers for distinguishing tuberculous pleural effusion from non-tuberculosis effusion: a retrospective study

    Background

    Pleural effusion (PE) is a common clinical feature that presents a diagnostic challenge for clinicians. In this retrospective study, we...

    Guo Fei, Mo Yijun, ... Liu Fang in BMC Infectious Diseases
    Article Open access 08 November 2023
  2. Pleural fluid adenosine deaminase to serum C-reactive protein ratio for diagnosing tuberculous pleural effusion

    Background

    Tuberculous pleural effusion (TPE) and malignant pleural effusion (MPE) may occasionally show similar cytological and biochemical picture...

    Mohammad Fazle Rabbi, Mushfiq Newaz Ahmed, ... Mohammad Azmain Iktidar in BMC Pulmonary Medicine
    Article Open access 15 September 2023
  3. Clinical significance of pleural fluid lactate dehydrogenase/adenosine deaminase ratio in the diagnosis of tuberculous pleural effusion

    Background

    Pleural fluid is one of the common complications of thoracic diseases, and tuberculous pleural effusion (TPE) is the most common cause of...

    Tingting Zhao, Jianhua Zhang, ... Cheng Wang in BMC Pulmonary Medicine
    Article Open access 15 May 2024
  4. Tuberculous pleural effusion-induced Arg-1+ macrophage polarization contributes to lung cancer progression via autophagy signaling

    Background

    The association between tuberculous fibrosis and lung cancer development has been reported by some epidemiological and experimental...

    Seong Ji Woo, Youngmi Kim, ... Ji Young Hong in Respiratory Research
    Article Open access 08 May 2024
  5. A scoring model for diagnosis of tuberculous pleural effusion

    Background

    Due to the low efficiency of a single clinical feature or laboratory variable in the diagnosis of tuberculous pleural effusion (TBPE), the...

    Senquan Wu, Shaomei Li, ... ** Zhang in BMC Pulmonary Medicine
    Article Open access 02 September 2022
  6. Diagnostic accuracy of pleural fluid lactate dehydrogenase to adenosine deaminase ratio for tuberculous pleural effusion: an analysis of two cohorts

    Background

    This study aimed to evaluate the diagnostic accuracy of pleural fluid (PF) lactate dehydrogenase (LDH) to adenosine deaminase (ADA)...

    Zhi Yan, Jian-Xun Wen, ... Wen-Qi Zheng in BMC Pulmonary Medicine
    Article Open access 19 November 2022
  7. Conditional diagnostic accuracy according to inflammation status and age for diagnosing tuberculous effusion

    Background

    Tuberculous effusion varies from lymphocyte-dominant to neutrophilic effusion according to inflammation status. The criteria of adenosine...

    Da Som Jeon, Sung-Hoon Kim, ... Hyung Jun Park in BMC Pulmonary Medicine
    Article Open access 20 October 2023
  8. Development and validation of a prediction model for tuberculous pleural effusion: a large cohort study and external validation

    Background

    Distinguishing tuberculous pleural effusion (TPE) from non-tuberculosis (TB) benign pleural effusion (BPE) remains to be a challenge in...

    Yanqing Liu, Zhigang Liang, ... Aihua Wu in Respiratory Research
    Article Open access 27 May 2022
  9. Application of ultrasound-guided medical thoracoscopy in patients with small amounts or without pleural effusion

    Background

    Pleural disease is a common clinical condition, and some patients present with a small amount of pleural effusion or no pleural effusion....

    Linhui Yang, Kaige Wang, ... Weimin Li in BMC Pulmonary Medicine
    Article Open access 19 January 2024
  10. Added value of 40 keV virtual monoenergetic images for diagnosing malignant pleural effusion on chest CT

    Objective

    This study aimed to evaluate the added value of 40 keV virtual mono-energetic images (VMIs) obtained from dual-layer detector CT (DLCT) for...

    Nahyeon Kim, Kyungsoo Bae, ... Kyung Nyeo Jeon in Japanese Journal of Radiology
    Article 03 May 2024
  11. Diagnostic value of SHOX2, RASSF1A gene methylation combined with CEA level detection in malignant pleural effusion

    Aim

    To investigate the diagnostic value of combined detection of SHOX2 and RASSF1A gene methylation with carcinoembryonic antigen (CEA) level in...

    Shaosen Chen, Kunlun Huang, ... Peicun Hu in BMC Pulmonary Medicine
    Article Open access 08 May 2023
  12. Tuberculous pleural effusion in a patient with sympathetic ophthalmia on immunosuppression: a case report

    Background

    Tuberculous pleural effusion (TPE) is paucibacillary, making its diagnosis difficult based on laboratory investigations alone. We present a...

    Dharshana Thiagarajan, Daphne Ai Lin Teh, ... Mae-Lynn Catherine Bastion in Tropical Diseases, Travel Medicine and Vaccines
    Article Open access 15 October 2021
  13. Characteristics of pleural effusion with a high adenosine deaminase level: a case–control study

    Background

    Increased pleural fluid adenosine deaminase (ADA) is useful for diagnosing tuberculous pleurisy (TB), but high ADA levels are associated...

    Masafumi Shimoda, Aya Hirata, ... Ken Ohta in BMC Pulmonary Medicine
    Article Open access 21 September 2022
  14. IR808@MnO nano-near infrared fluorescent dye’s diagnostic value for malignant pleural effusion

    Background

    Malignant pleural effusion is mostly a complication of advanced malignant tumors. However, the cancer markers such as carbohydrate antigen...

    **aoqiong Wang, **ngya Yan, ... Yongsheng Wang in Respiratory Research
    Article Open access 09 January 2024
  15. Age affects the diagnostic accuracy of the cancer ratio for malignant pleural effusion

    Background and objective

    Cancer ratio (CR), which is defined as serum lactate dehydrogenase (LDH) to pleural fluid adenosine deaminase (ADA) ratio,...

    **-Hong Huang, Hong Chen, ... Ting-Wang Jiang in BMC Pulmonary Medicine
    Article Open access 07 June 2023
  16. The yield of rigid thoracoscopy in patients of undiagnosed exudative pleural effusion and comparison of pleural fluid and thoracoscopic findings between tuberculosis and malignancy

    Background

    Medical thoracoscopy is an essential tool in the evaluation of patients with pleural effusion who remain undiagnosed despite a thorough...

    Hemant Kumar, Mohammad Arif, ... R. A. S. Kushwaha in The Egyptian Journal of Bronchology
    Article Open access 03 November 2023
  17. New biomarkers for the diagnosis of pleural effusion

    Background

    Persistent undiagnosed effusion is present in approximately 15% of all causes of exudative effusion. Pleural effusion caused by...

    Raafat T. El-Sokkary, Nermen M. Abuelkassem, ... Ahmed Metwally in The Egyptian Journal of Bronchology
    Article Open access 21 June 2022
  18. Development and validation of a radiomics nomogram for diagnosis of malignant pleural effusion

    Objective

    We aimed to develop a radiomics nomogram based on computed tomography (CT) scan features and high-throughput radiomics features for...

    Mingzhu Wei, Ya** Zhang, ... Zhenhua Zhao in Discover Oncology
    Article Open access 24 November 2023
  19. Assessment of diaphragmatic role in dyspneic patients with pleural effusion

    Background

    Dyspnea that is caused by pleural effusion and affects patients’ quality of life may not be resolved after lung expansion following pleural...

    Heba Mohamed Shalaby, Hieba Gamal Ezzelregal in The Egyptian Journal of Bronchology
    Article Open access 21 December 2022
  20. Evaluation of serum and pleural levels tumor M2-pyruvate kinase in lung cancer patients with pleural effusion

    Objective

    To evaluate the diagnostic value of tumor M2-pyruvate kinase (TuM2-PK) and carcinoembryonic antigen (CEA) levels in both pleural effusion...

    Tiantian Zhang, Wei Liu, ... Chunhua Xu in BMC Pulmonary Medicine
    Article Open access 10 August 2022
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