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Advances in the pathogenesis and therapeutic strategies of angioimmunoblastic T-cell lymphoma
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive subtype of peripheral T-cell lymphomas with its cell origin determined to be follicular...
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Therapeutic advantage of teriparatide in very elderly patients with proximal femoral fractures: a functional and BMD analysis
BackgroundTeriparatide, a recombinant parathyroid hormone, is pivotal in osteoporosis treatment, particularly in post-surgical recovery for hip...
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Non-Surgical Therapeutic Strategies for Non-Melanoma Skin Cancers
Non-melanoma skin cancer (NMSC) is a globally prevalent skin disease, with basal cell carcinoma and squamous cell carcinoma accounting for 99% of...
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Therapeutic anticoagulation complications in the elderly: a case report
BackgroundThe demographic transition leads to a continuously growing number of elderly patients who receive therapeutic anticoagulation by reason of...
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Bone cement reinforcement improves the therapeutic effects of screws in elderly patients with pelvic fragility factures
BackgroundPelvic fragility fractures in elderly individuals present significant challenges in orthopedic and geriatric medicine due to reduced bone...
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Current and emerging therapeutic strategies in adult T-cell leukemia–lymphoma
Adult T-cell leukemia–lymphoma (ATL) is classified into four clinical subtypes: acute, lymphoma, chronic, and smoldering. Chronic ATL is further...
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Impact of cancer diagnosis and treatment: a qualitative analysis of strains, resources and co** strategies among elderly patients in a rural setting in Ghana
BackgroundRurality is fraught with numerous difficulties including a lack of advanced health facilities to provide health services, and an absence of...
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Improving survival in metastatic renal cell carcinoma (mRCC) patients: do elderly patients benefit from expanded targeted therapeutic options?
IntroductionTreatment advances in metastatic renal cell carcinoma (mRCC) have improved overall survival (OS) in mRCC patients over the last two...
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Non-Melanoma Skin Cancer Treatment Updates in the Elderly
Purpose of ReviewThis review article highlights recent advancements in the treatment of non-melanoma skin cancer (NMSC), focusing on efficacy and...
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Methylation across the central dogma in health and diseases: new therapeutic strategies
The proper transfer of genetic information from DNA to RNA to protein is essential for cell-fate control, development, and health. Methylation of...
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Central serous chorioretinopathy: updates in the pathogenesis, diagnosis and therapeutic strategies
Central serous chorioretinopathy (CSCR), first described by Albrecht von Graefe in 1866, is characterized by focal serous detachment of the neural...
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Signaling cascades in the failing heart and emerging therapeutic strategies
Chronic heart failure is the end stage of cardiac diseases. With a high prevalence and a high mortality rate worldwide, chronic heart failure is one...
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Prognostic analysis and treatment utilization of different treatment strategies in elderly esophageal cancer patients with distant metastases: a SEER database analysis
PurposeThe purpose of this study was to explore which therapeutic strategy is more beneficial for elderly esophageal cancer (EC) patients with...
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The pathogenesis and therapeutic strategies of heat stroke-induced liver injury
Heat stroke (HS) is a life-threatening systemic disease characterized by an elevated core body temperature of more than 40 ℃ and subsequent multiple...
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Kidney biopsy in very elderly patients: indications, therapeutic impact and complications
BackgroundFew data is available on the risk/benefit balance of native kidney biopsy (KB) in very elderly patients.
MethodsMulticenter retrospective...
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Nomogram predictive model for in-hospital mortality risk in elderly ICU patients with urosepsis
BackgroundUrinary tract infection (UTI) is a common cause of sepsis. Elderly patients with urosepsis in intensive care unit (ICU) have more severe...
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Linezolid dose adjustment according to therapeutic drug monitoring helps reach the goal concentration in severe patients, and the oldest seniors benefit more
BackgroundThe elderly with severe infection increased dramatically in intensive care unit (ICU). Proper antimicrobial therapy help improve the...
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Sociodemographic features associated with the MoCA, SPPB, and GDS scores in a community-dwelling elderly population
BackgroundAn accurate evaluation of cognitive function, physical health, and psychological health is fundamental for assessing health problems in the...
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Title: Pruritus in the Elderly: Differential Diagnosis and Management
Purpose of ReviewPruritis is a highly prevalent symptom in older adults significantly impacting their quality of life. It can manifest in the...
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Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives
Purpose of ReviewPostherpetic neuralgia is an annoying pain that mainly affects older people. In order to give patients more options, this review...
