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Neuroprotektive Therapien bei idiopathischen, genetischen und atypischen Parkinson-Syndromen mit α-Synuklein – Pathologie
The key aspect of the classification of neurodegenerative diseases is the histopathological detection of certain proteins in the brain. The various...
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Therapie – Quo vadis Neurodegeneration?
BackgroundHallmarks of neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease are pathological protein aggregation,...
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Parkinson- und Alzheimer-Erkrankung als Systemerkrankungen
BackgroundParkinson’s and Alzheimer’s disease (PD/AD) are characterized by cellular pathological changes that precede clinical manifestation and...
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Fokus atypische Parkinsonsyndrome: Teil 1 – Multisystematrophie
Multisystem atrophy is a neurodegenerative disorder belonging to the atypical Parkinsonian syndromes and is rare with an incidence of 5/100,000. It...
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Zusammenhänge zwischen Mikrobiom und Neurodegeneration
BackgroundNeurodegenerative diseases are often associated with changes in the (gut) microbiome.
ObjectiveBased on studies in Parkinson’s disease...
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Schlafstörungen bei Parkinson-Krankheit
Sleep of patients with Parkinson’s disease (PD) is affected by both motor and non-motor symptoms; the neurodegeneration causes alterations in...
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Dysphagie bei Parkinson-Syndromen
Dysphagia is a clinically relevant problem in Parkinson’s disease as well as in atypical Parkinsonian syndromes, such as multiple system atrophy and...
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Prognostischer und differenzialdiagnostischer Stellenwert der Liquordiagnostik bei neurodegenerativen Demenzerkrankungen
Cerebrospinal fluid (CSF) analysis is an important diagnostic tool in the assessment of dementia. For the differentiation of Alzheimer’s disease from...
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Atypische Parkinson-Syndrome im Alter
Atypical Parkinson syndromes represent a neuropathologically heterogeneous group and include the clinical entities dementia with Lewy bodies (DLB),...
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Parkinson-Krankheit
Parkinson’s disease (PD) is an unparalleled example of a neurodegenerative disorder that can be effectively managed leading to sustained symptom...
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