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Onasemnogene Abeparvovec for Treating Pre-symptomatic Spinal Muscular Atrophy: An External Assessment Group Perspective of the Partial Review of NICE Highly Specialised Technology Evaluation 15
As part of the National Institute for Health and Care Excellence (NICE) highly specialised technology (HST) evaluation programme, Novartis submitted...
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Presence of intracellular bacterial communities in uroepithelial cells, a potential reservoir in symptomatic and non-symptomatic people
BackgroundUrinary tract infection is one of the most common infections in humans, affecting women in more proportion. The bladder was considered...
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Maternal and Neonatal Outcomes for Mothers with Symptomatic Hydronephrosis of Pregnancy Managed with Percutaneous Nephrostomy with Comparison High-Risk Pregnancy Group
PurposeSymptomatic hydronephrosis of pregnancy (SHOP) presents with flank pain but may include fever, bacteremia, or sepsis that is harmful to the...
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Outcomes of robotic-assisted pyeloplasty in symptomatic versus asymptomatic patients
ObjectiveTo evaluate the outcome of robotic-assisted laparoscopic pyeloplasty (RAP) in symptomatic patients with ureteropelvic junction obstruction...
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Comparative analysis of discoid lateral meniscus size: a distinction between symptomatic and asymptomatic cases
PurposeThis study evaluated the differences in meniscal sizes and occupancy between symptomatic and asymptomatic patients diagnosed with discoid...
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Symptomatic vs. non-symptomatic device-related thrombus after LAAC: a sub-analysis from the multicenter EUROC-DRT registry
BackgroundDevice-related thrombus (DRT) after left atrial appendage closure (LAAC) is associated with adverse outcomes, i.e. ischemic stroke or...
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Structural alterations of spinocerebellar ataxias type 3: from pre-symptomatic to symptomatic stage
ObjectivesTo investigate and characterize the structural alterations of the brain in SCA3, and their correlations with the scale for the assessment...
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Neutrophil-to-lymphocyte ratio associated with symptomatic saccular unruptured intracranial aneurysm
Background and purposeWhether symptomatic unruptured intracranial aneurysms (UIAs) lead to change in circulating inflammation remains unclear. This...
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Pregnancy is associated with reduced progression of symptomatic adenomyosis: a retrospective pilot study
BackgroundAdenomyosis is a common gynecological disease in women of reproductive age and causes various symptoms such as dysmenorrhea and heavy...
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Cardiovascular reflex tests detect autonomic dysfunction in symptomatic and pre-symptomatic subjects with hereditary transthyretin amyloidosis
PurposeAutonomic dysfunction is a distinctive but undervalued feature of hereditary transthyretin amyloidosis (ATTRv). It may predate the onset of...
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Factors affecting the need for ureteral catheterization in symptomatic pregnancy hydronephrosis
PurposeIn our study, considering the clinical parameters we aimed to determine the most appropriate treatment approach for symptomatic gestational...
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Nasal and Serum Immunoglobulin E Levels in Symptomatic Allergic Rhinitis Patients: A Case–Control Study
Allergic Rhinitis (AR) is an inflammatory condition of the nasal mucosa triggered by Immunoglobulin E (IgE) mediated response to exposure to...
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Patterns of use of symptomatic treatments for Alzheimer's disease dementia (AD)
BackgroundSymptomatic treatment for Alzheimer's disease (AD) dementia could temporarily slow symptom worsening and improve the quality of life for...
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Effects of group mindfulness-based cognitive therapy and group cognitive behavioural therapy on symptomatic generalized anxiety disorder: a randomized controlled noninferiority trial
BackgroundMindfulness-based cognitive therapy (MBCT) is a promising alternative treatment for generalized anxiety disorder (GAD). The objective of...
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Increased subtalar rotational motion in patients with symptomatic ankle instability under load and stress conditions
PurposeDifferentiating subtalar and ankle instability in the clinical setting is challenging. This study aims to analyze the rotational laxity of the...
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Acute symptomatic seizures in newborns: a narrative review
Acute symptomatic seizures are the main sign of neurological dysfunction in newborns. This is linked to the unique characteristics of the neonatal...
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Perioperative complications of symptomatic congenital kyphosis: a retrospective cohort study
BackgroundDespite the recent improvements in the surgical treatment of congenital kyphosis, this surgery may be associated with high rate of...
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Study protocol for the implementation of Centering Patients with Fibroids, a novel group education and empowerment program for patients with symptomatic uterine fibroids
BackgroundBlack women and people with uteri have utilized collectivistic and relational practices to improve health outcomes in the face of medical...
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Using a modified nominal group technique to develop complex interventions for a randomised controlled trial in children with symptomatic pes planus
BackgroundChildren with symptomatic flat feet (pes planus) frequently present for care but there remains uncertainty about how best to manage their...
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A dynamic nomogram predicting symptomatic pneumonia in patients with lung cancer receiving thoracic radiation
PurposeThe most common and potentially fatal side effect of thoracic radiation therapy is radiation pneumonitis (RP). Due to the lack of effective...
