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Clinical Utility of Sperm Function Tests in Predicting Male Fertility: A Systematic Review
Routine semen analysis provides considerable information regarding sperm parameters; however, it is not solely adequate to predict male fertility...
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Cannabidiol impairs sperm quality and function in adult mice
BackgroundConsidering the growing therapeutic use of cannabidiol as well as the presence of cannabinoid receptors in sperm and its possible genotoxic...
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Effect of Advanced Glycation end Products (AGEs) on Sperm Parameters and Function in C57Bl/6 Mice
This study investigated the deleterious impact of advanced glycation end products (AGEs), commonly present in metabolic disorders like diabetes,...
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Sperm chromatin structure assay (SCSA®) and flow cytometry-assisted TUNEL assay provide a concordant assessment of sperm DNA fragmentation as a function of age in a large cohort of approximately 10,000 patients
BackgroundSperm DNA integrity is increasingly seen as a critical characteristic determining reproductive success, both in natural reproduction and in...
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Sperm Preparation with Microfluidic Sperm Sorting Chip May Improve Intracytoplasmic Sperm Injection Outcomes Compared to Density Gradient Centrifugation
Does sperm preparation using the FERTILE PLUS™ Sperm Sorting Chip improve fertilization rates, blastocyst formation, utilization, and euploidy rates...
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Sexual function in heterosexual couples undergoing assisted reproductive technology (ART) cycles with donor sperm
PurposeSexuality and the desire for children are closely linked, and infertility can increase the risk of sexual dysfunction (SD). Among heterosexual...
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The evaluation effect of nanoliposome-loaded Mito-Tempo on sperm parameters during human sperm cryopreservation
AimThe aim of this study is the evaluation effect of nanoliposome-loaded Mito-Tempo on sperm parameters during human sperm cryopreservation.
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Sexual function in male cancer survivors is not correlated to sperm quality
PurposeBoth infertility and erectile dysfunction (ED) are known long-term consequences of cancer treatment in young male cancer survivors. In the...
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A loss-of-function variant in ZCWPW1 causes human male infertility with sperm head defect and high DNA fragmentation
BackgroundMale infertility is a global health issue. The more causative genes related to human male infertility should be further explored. The...
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Optimized sperm selection: a highly efficient device for the isolation of progressive motile sperm with low DNA fragmentation index
PurposeTo identify the sperm preparation procedure that selects the best sperm population for medically assisted reproduction.
MethodsProspective...
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A Prediction Model of Sperm Retrieval in Males with Idiopathic Non-obstructive Azoospermia for Microdissection Testicular Sperm Extraction
Patients with Idiopathic non-obstructive azoospermia (iNOA) can achieve fertility by extracting testicular sperm through microdissection testicular...
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Taurine Improves Sperm Mitochondrial Indices, Blunts Oxidative Stress Parameters, and Enhances Steroidogenesis and Kinematics of Sperm in Lead-Exposed Mice
Lead (Pb) is a highly toxic heavy metal. Pb exposure could adversely affect many organs, including the male reproductive system. Oxidative stress and...
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Camellia oil with its rich in fatty acids enhances post-thawed boar sperm quality
BackgroundBoar sperm are highly susceptible to specific conditions during cryopreservation, leading to a significant decrease in their fertilizing...
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Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats
BackgroundData available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the...
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Understanding sperm motility mechanisms and the implication of sperm surface molecules in promoting motility
BackgroundIt is estimated that approximately 8–12% of couples globally face problems associated with infertility. A large number of men exhibit...
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The correlation between sperm percentage with a small acrosome and unexplained in vitro fertilization failure
PurposeSince the unexplained in vitro fertilization failure occurs frequently, it is of great importance and clinical value to identify potential...
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Epididymal RNase T2 contributes to astheno-teratozoospermia and intergenerational metabolic disorder through epididymosome-sperm interaction
BackgroundThe epididymis is crucial for post-testicular sperm development which is termed sperm maturation. During this process, fertilizing ability...
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Relationship between degree of methylation of sperm long interspersed nuclear element-1 (LINE-1) gene and alteration of sperm parameters and age: a meta-regression analysis
IntroductionThe long interspersed nuclear element-1 ( LINE1 ) gene is a retrotransposon whose methylation status appears to play a role in...
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Emerging trends in sperm selection: enhancing success rates in assisted reproduction
This comprehensive review explores the evolving landscape of sperm selection techniques within the realm of Assisted Reproductive Technology (ART)....
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Chronically high stress hormone levels dysregulate sperm long noncoding RNAs and their embryonic microinjection alters development and affective behaviours
Previous studies on paternal epigenetic inheritance have shown that sperm RNAs play a role in this type of inheritance. The microinjection of sperm...
