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Management of moderate to severe traumatic brain injury: an update for the intensivist
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the world. Current clinical management in severe TBI...
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Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage
BackgroundThe objective of this document is to provide recommendations on the formal reliability of major clinical predictors often associated with...
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Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study
BackgroundIn patients with severe brain injury, withdrawal of life-sustaining measures (WLSM) is common in intensive care units (ICU). WLSM...
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Predicting Coma Trajectories: The Impact of Bias and Noise on Shared Decisions
Coma trajectories are characterized by quick awakening or protracted awakening. Outcome is bookended by restored functionality or permanent...
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Ethics Priorities of the Curing Coma Campaign: An Empirical Survey
BackgroundThe Curing Coma Campaign (CCC) is a multidisciplinary global initiative focused on evaluation, diagnosis, treatment, research, and...
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Clinical outcomes and end-of-life treatment in 596 patients with isolated traumatic brain injury: a retrospective comparison of two Dutch level-I trauma centers
PurposeWith an increasingly older population and rise in incidence of traumatic brain injury (TBI), end-of-life decisions have become frequent. This...
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Frailty assessment in critically ill older adults: a narrative review
Frailty, a condition that was first defined 20 years ago, is now assessed via multiple different tools. The Frailty Phenotype was initially used to...
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Performance of a guideline-recommended algorithm for prognostication of poor neurological outcome after cardiac arrest
PurposeTo assess the performance of a 4-step algorithm for neurological prognostication after cardiac arrest recommended by the European...
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Standardised and automated assessment of head computed tomography reliably predicts poor functional outcome after cardiac arrest: a prospective multicentre study
PurposeApplication of standardised and automated assessments of head computed tomography (CT) for neuroprognostication after out-of-hospital cardiac...
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Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury
BackgroundModerate–severe traumatic brain injury (msTBI) carries high morbidity and mortality worldwide. Accurate neuroprognostication is essential...
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An Update on Palliative Care in Neurocritical Care: Providing Goal-Concordant Care in the Face of Prognostic Uncertainty
Purpose of reviewWe investigate the complexities and interplay between the concepts of prognostic uncertainty and patient preferences as they relate...
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Early Shared Decision-Making for Older Adults with Traumatic Brain Injury: Using Time-Limited Trials and Understanding Their Limitations
Older adults account for a disproportionate share of the morbidity and mortality after traumatic brain injury (TBI). Predicting functional and...
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Long-Term Outcomes of Patients with Stroke Predicted by Clinicians to have no Chance of Meaningful Recovery: A Japanese Cohort Study
BackgroundLittle is known about the natural history of comatose patients with brain injury, as in many countries most of these patients die in the...
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Critically ill metastatic cancer patients returning home after unplanned ICU stay: an observational, multicentre retrospective study
BackgroundData about critically ill metastatic cancer patients functional outcome after unplanned admission to the ICU are scarce. The aim of this...
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Physician experience improves ability to predict 6-month functional outcome of severe traumatic brain injury
BackgroundThe functional prognosis of severe traumatic brain injury (TBI) during the acute phase is often poor and uncertain. We aimed to quantify...
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Prognostication of ICU Patients by Providers with and without Neurocritical Care Training
BackgroundPredictions of functional outcome in neurocritical care (NCC) patients impact care decisions. This study compared the predictive values...
