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Health-related quality of life in Chinese SLE patients: evidence from 1568 SLE patients and 2610 healthy controls
ObjectiveTo investigate the effects of systemic lupus erythematosus (SLE) on health-related quality of life (HRQOL), the relationship between disease...
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Possible Role of Dysbiosis of the Gut Microbiome in SLE
Purpose of ReviewThe resident gut microbiota serves as a double-edged sword that aids the host in multiple ways to preserve a healthy equilibrium and...
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Subclinical pleuro-pulmonary disease in patients with SLE: functional and radiological methods
BackgroundSystemic lupus erythematosus (SLE) is a multisystem autoimmune disease with highest prevalence of chest involvement; however, early...
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Targeting DORIS Remission and LLDAS in SLE: A Review
Remission is the established therapeutic goal for patients with systemic lupus erythematosus (SLE) and is currently defined by the widely adopted...
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Evaluation of Type 2 SLE symptoms in patients with a range of lupus nephritis activity
BackgroundType 2 systemic lupus erythematosus (SLE) symptoms, including fatigue, fibromyalgia, and brain fog, contribute to poor health-related...
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Genetics of SLE: mechanistic insights from monogenic disease and disease-associated variants
The past few years have provided important insights into the genetic architecture of systemic autoimmunity through aggregation of findings from...
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Interaction of 5-HTTLPR and SLE disease status on resting-state brain function
BackgroundNeuropsychiatric involvement in systemic lupus erythematosus (SLE) is a common clinical manifestation. In SLE patients, cerebral function...
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Platelet ındices as potential biomarkers of perinatal outcomes in women with SLE during pregnancy
AimThis study aimed to assess the platelet parameters and their prognostic value for perinatal outcomes in pregnant women with systemic lupus...
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Negative ANA-IIF in SLE patients: what is beyond?
AbstractThe antinuclear antibody (ANA) test has high sensitivity in diagnosing and classifying systemic lupus erythematosus (SLE).
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Identification of EPSTI1 as a new potential biomarker for SLE based on GEO database
ObjectiveSystemic lupus erythematosus (SLE) is a chronic autoimmune disease with highly heterogeneous. The aim of this study is to find the key genes...
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Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients
Systemic lupus erythematosus (SLE) is a common autoimmune disease with a polymorphic clinical presentation involving multisystem damages with...
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Pattern of disease expression in SLE patients with antiphospholipid antibodies: data from Indian Systemic Lupus Erythematosus Inception cohort (INSPIRE)
Antiphospholipid antibodies (APLA) are present in one-third of systemic lupus erythematosus (SLE) patients, and they are associated with both...
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Presentation of SLE after COVID vaccination in a pediatric patient
BackgroundThe outbreak of severe acute respiratory syndrome coronavirus 2 has had an enormous impact on global health. Vaccination remains one of the...
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YKL-40 in serum: a promising biomarker of juvenile SLE and strongly correlated with disease duration
BackgroundThe biological function of YKL-40 is not well determined in different inflammatory and autoimmune diseases; however, some data highlighted...
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Obesity and tobacco smoking are independently associated with poor patient-reported outcomes in SLE: a cross-sectional study
We investigated associations of obesity and tobacco smoking with health-related quality of life (HRQoL), pain, fatigue, and functional impairment in...
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Assessment of peripapillary retinal nerve fiber layer thickness and vessel density in newly diagnosed SLE patients without ocular symptoms
PurposeThis study aims to assess peripapillary retinal nerve fiber layer thickness (pRNFLT) and peripapillary vessel density (PVD) in patients with...
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Using PROMIS-29 to determine symptom burdens in the context of the Type 1 and 2 systemic lupus erythematosus (SLE) model: a cross sectional study
ObjectiveTo account for heterogeneity in systemic lupus erythematosus (SLE) and bridge discrepancies between patient- and physician-perceived SLE...
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Nailfold capillaroscopy in Egyptian systemic lupus erythematosus (SLE) patients: correlation with demographic features and serum levels of IL 17A and IFNs I
BackgroundIn SLE patients, cytokines are linked to endothelial cell damage. Nailfold capillaroscopy (NFC) is a simple method for evaluating...
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Emerging concepts of type I interferons in SLE pathogenesis and therapy
Type I interferons have been suspected for decades to have a crucial role in the pathogenesis of systemic lupus erythematosus (SLE). Evidence has now...
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Development and validation of the systemic lupus erythematous scale amongst the system of quality of life instruments for chronic diseases QLICD-SLE (V2.0)
ObjectiveThe present study is aimed to develop and validate a quality of life scale for systemic lupus erythematosus (SLE) patients with Chinese...
