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Progress of iPS cell-based transplantation therapy for retinal diseases
The discovery of induced Pluripotent Stem) (iPS) cells has instigated innovation in various fields, including ophthalmology. Cell therapy has shown...
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Ex vivo cultivated retinal pigment epithelial cell transplantation for the treatment of rabbit corneal endothelial dysfunction
ObjectiveStem cell therapy is a promising strategy for the treatment of corneal endothelial dysfunction, and the need to find functional alternative...
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Destructive inflammatory reaction after an autologous retinal pigment epithelium and choroid transplantation: no detection of an auto-immune response
PurposeFive patients who underwent uncomplicated retinal pigment epithelium (RPE)-choroid transplantation for neovascular age-related macular...
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Epiretinal Amniotic Membrane in Complicated Retinal Detachment: a Clinical and In Vitro Safety Assessment
IntroductionAmniotic membrane (AM) is a popular treatment for external ocular diseases. First intraocular implantations in other diseases reported...
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Analysis of retinal and choroidal microvascular changes using optical coherence tomography and optical coherence tomography angiography in patients with acute leukemia
PurposeAlthough leukemic retinopathy accounts for 80% of ocular complications in acute leukemia, its pathogenesis remains unclear. To evaluate...
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Clinical Considerations for RPE Cell Transplantation
Purpose of ReviewTransplantation of retinal pigment epithelium (RPE) derived from either induced pluripotent stem cells (iPSCs) or embryonic stem...
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Shortfalls of free autologous internal limiting membrane transplantation for highly myopic refractory macular holes in a long term follow-up
BackgroundThe aim of this study is to evaluate long-term anatomical and functional outcomes of autologous internal limiting membrane (ILM)...
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Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond
This comprehensive review provides a thorough examination of inherited retinal diseases (IRDs), encompassing their classification, genetic...
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The developments in amniotic membrane transplantation in glaucoma and vitreoretinal procedures
The main reasons why Amniotic Membrane (AM) is transplanted in Ophthalmology are: to provide a substrate for cellular growth and to provide tectonic...
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Early retinal neurovascular findings in post-transplant diabetes mellitus patients without clinical signs of diabetic retinopathy
BackgroundPost-transplant diabetes mellitus (PTDM) is a specific subtype of diabetes with an uncertain impact on mortality and morbidity in...
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Autologous neurosensory retinal transplantation for large refractory idiopathic macular hole
PurposeTo investigate the structural and functional reconstruction of the macula after autologous neurosensory retinal-free flap transplantation...
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The retinal phenotype in primary hyperoxaluria type 2 and 3
BackgroundThe primary hyperoxalurias (PH1-3) are rare inherited disorders of the glyoxylate metabolism characterized by endogenous overproduction of...
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Retrospective case series of high-density silicone oil (Oxane HD) in severe proliferative vitreorretinal retinal detachment patients
BackgroundDescribe complications and clinical outcomes of heavy silicone oil (HSO) Oxane HD® use as an alternative to overcome the challenges of...
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Retinal neurovascular alteration in type 2 diabetes with renal impairment in association with systemic arterial stiffness
BackgroundDiabetic retinopathy (DR) patients should be alert for subclinical macroangiopathy. We aimed to investigate the association between retinal...
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Ocular characteristics and outcomes of phacoemulsification in patients with cataract after renal transplantation
PurposeTo explore ocular characteristics of patients with cataracts after renal transplantation and analyze the results of phacoemulsification...
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A rabbit model for outer retinal atrophy caused by surgical RPE removal
PurposeWe aimed to establish a rabbit model with retinal atrophy induced by an iatrogenic retinal pigment epithelium (RPE) removal, for future...
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Gene Therapy Activates Retinal Pigment Epithelium Cell Proliferation for Age-related Macular Degeneration in a Mouse Model
ObjectiveAge-related macular degeneration (AMD) is a degenerative retinal disease. The degeneration or death of retinal pigment epithelium (RPE)...
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Advances in the ocular complications after hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation (HSCT) has benefited an increasing number of patients with hematological disease in the clinic. It is a...
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Diverse retinal-kidney phenotypes associated with NPHP1 homozygous whole-gene deletions in patients with kidney failure
A precise diagnosis in medicine allows appropriate disease-specific management. Kidney failure of unknown aetiology remains a frequent diagnostic...
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Retinal changes of primary vitreoretinal lymphoma after intravitreal methotrexate
BackgroundTo identify retinal changes using spectral-domain optical coherence tomography (SD-OCT) and ultra-widefield images in eyes with primary...
