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Ocular characteristics and outcomes of phacoemulsification in patients with cataract after renal transplantation

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Abstract

Purpose

To explore ocular characteristics of patients with cataracts after renal transplantation and analyze the results of phacoemulsification combined with intraocular lens (IOL) implantation.

Methods

Patients with cataracts after renal transplantation and control patients who underwent phacoemulsification combined with IOL implantation were enrolled. All patients underwent phacoemulsification combined with IOL implantation. Visual acuity, intraocular pressure, type of lens opacity, corneal endothelial cell density, and ocular biological parameters were evaluated before surgery. Visual prognosis, dry eye, and postoperative complications were monitored for 6 months after phacoemulsification.

Results

We analyzed 25 eyes of 16 patients after renal transplantation and 30 eyes of 21 control patients. The most common type of cataract of renal transplantation group was posterior subcapsular, while the most common type of cataract of control group was cortical. Significant differences in corneal astigmatism, white-to-white ratio, and keratometry values were observed between the groups. The postoperative visual acuity of both groups significantly improved following surgery. Postoperative complications, such as the degree of anterior and posterior capsule opacification and the incidence of a requirement of neodymium-doped yttrium aluminum garnet laser capsulotomy, were significantly lower in the renal transplantation group. Moreover, secondary glaucoma occurred in two eyes in the renal transplantation group.

Conclusion

This study showed that cataracts after renal transplantation were mostly posterior subcapsular. Postoperative visual acuity recovered well in most patients, with reduced incidence of postoperative complications. This study suggested that phacoemulsification combined with IOL implantation was safe and effective, providing a reference for multi-focal IOL implantation in kidney transplant recipients.

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Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript. This study did not receive external funding.

Author information

Author notes

  1. Yilin Chen and **xiao Yang share first authorship.

Authors and Affiliations

  1. Department of Ophthalmology, The First Affiliated Hospital of Sun Yat-sen University, 58 Zhongshan 2nd Road, Yuexiu District, Guangzhou City, 510080, Guangdong Province, People’s Republic of China

    Yilin Chen, **xiao Yang, Wentao Li & Lijun Huo

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  1. Yilin Chen
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  2. **xiao Yang
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  3. Wentao Li
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  4. Lijun Huo
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Contributions

YC and LH contributed to the study conception and design. YC, PY and WL collected and analyzed the data. YC and PY wrote the first draft of the manuscript. LH reviewed the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Lijun Huo.

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Competing interests

The authors have no relevant financial or non-financial interests to disclose.

Consent to participate

Informed consent was obtained from all individual participants included in the study.

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The authors affirm that human research participants provided informed consent for publication of the images in Figs. 1 and 2.

Ethical approval

The study was approved by the Ethics Committee of the First Affiliated Hospital of Sun Yat-sen University in China (IIT-2022-256) and complied with the tenets of the Declaration of Helsinki for Biomedical Research Involving Human Subjects.

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Chen, Y., Yang, P., Li, W. et al. Ocular characteristics and outcomes of phacoemulsification in patients with cataract after renal transplantation. Int Ophthalmol 44, 255 (2024). https://doi.org/10.1007/s10792-024-03161-2

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