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Comparison of vonoprazan dual therapy, quadruple therapy and standard quadruple therapy for Helicobacter pylori infection in Hainan: a single-center, open-label, non-inferiority, randomized controlled trial
ObjectiveTo compare the potential efficacy and safety of dual therapy and quadruple therapy with vonoprazan (VPZ) as well as the standard quadruple...
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Beyond quadruple therapy: the potential roles for ivabradine, vericiguat, and omecamtiv mecarbil in the therapeutic armamentarium
Quadruple therapy is effective for patients with heart failure with reduced ejection fraction, providing significant clinical benefits, including...
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Efficacy comparison of 7- and 14-day P-CAB based bismuth-containing quadruple regimen with PPI based bismuth-containing quadruple regimen for Helicobacter pylori infection: rationale and design of an open-label, multicenter, randomized controlled trial
BackgroundOwing to its strong acid inhibition, potassium-competitive acid blocker (P-CAB) based regimens for Helicobacter pylori ( H. pylori )...
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Bismuth-Containing Quadruple Therapy for Helicobacter pylori Eradication: A Randomized Clinical Trial of 10 and 14 Days
BackgroundBismuth-containing quadruple therapy is the first-line treatment for eradicating Helicobacter pylori ( H. pylori ). The optimal duration for H...
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Comparison of the efficacies of triple, quadruple and sequential antibiotic therapy in eradicating Helicobacter pylori infection: A randomized controlled trial
Background and AimThere is regional variation in the eradication rates of Helicobacter pylori ( H. pylori ) regimens depending on the local antibiotic...
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Efficacy and safety of bifidobacterium quadruple viable tablets in the treatment of Helicobacter pylori-infected peptic ulcer or gastritis patients: a systematic review and meta-analysis
BackgroundTo better understand the efficacy and safety of Bifidobacterium quadruple viable tablets in the treatment of helicobacter pylori ( H. pylori ...
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Can vitamin B6 alleviate the adverse reactions of quadruple anti-Helicobacter pylori regimen? : randomized controlled trial
BackgroundVitamin B6 is an essential water-soluble vitamin for humans. It is often used to prevent a variety of neuropathies, relieve vomiting, and...
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Efficacy and safety of Bifidobacterium quadruple viable tablets combined with mosapride citrate in the treatment of constipation in China: a systematic review and meta-analysis
AimTo analyze the efficacy and safety of Bifidobacterium quadruple viable tablets combined with mosapride citrate for the treatment of constipation.
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Advancing Primary Care Access: Exploring the Impact of the Virtual Waiting Room on the Quadruple Aim
BackgroundCommunity health centers grapple with high no-show rates, posing challenges to patient access and primary care provider (PCP) utilization.
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Quadruple pharmacotherapy for alcohol use disorder tolerable yet insufficient: a case report
BackgroundCombinations of alcohol use disorder (AUD) medications have been investigated, but few if any reports describe patients maintained on more...
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Initial treatment with a single capsule containing half-dose quadruple therapy versus standard-dose dual therapy in hypertensive patients (QUADUAL): statistical analysis plan for a randomized, blinded, crossover trial
BackgroundCombined antihypertensive therapy has obvious advantages over single drug therapy. Hypertension guidelines fully affirm the efficacy of...
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Minocycline vs. tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori rescue treatment: a multicentre, randomized controlled trial
BackgroundTo compare the efficacy and tolerability of minocycline vs. tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori ( H...
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Combined maternal risk factors and the Quadruple test to predict late-onset preeclampsia in pregnant Thai women
BackgroundThis study aimed to evaluate the predictive power of a model combining maternal risk factors and the Quadruple screen test for late-onset...
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Vonoprazan-based triple and dual therapy versus bismuth-based quadruple therapy for Helicobacter pylori infection in China: a three-arm, randomised clinical trial protocol
BackgroundHelicobacter pylori infection and associated diseases are a growing global public health issue. H. pylori infection is the major cause of...
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Evidence on bringing specialised care to the primary level—effects on the Quadruple Aim and cost-effectiveness: a systematic review
BackgroundTo achieve the Quadruple Aim of improving population health, enhancing the patient experience of care, reducing costs and improving...
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The cure rate of 10-day bismuth-containing quadruple therapy for Helicobacter pylori eradication is equivalent to 14-day: a systematic review and meta-analysis
Helicobacter pylori ( H. pylori ) infection is a major cause of duodenal ulcers, gastric ulcers, and gastric cancer. However, the optimal duration for H....
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The Safety and Efficacy of Quadruple Ultra-Low-Dose Combination (Quadpill) for Hypertension Treatment: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background and ObjectiveQuadpill, a single pill containing a quadruple combination of quarter doses of four antihypertensive agents, has been...
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Efficacy and Safety of 7-Day Non-Bismuth Concomitant Quadruple Therapy for First-Line Helicobacter pylori Eradication in the Elderly
BackgroundAging may affect the efficacy of Helicobacter pylori eradication. The aim of our study was to assess the efficacy and safety of 7-day...
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Quadruple term gestation of quadri-chorionic quadri-amniotic pregnancy after artificial insemination: a case report
BackgroundTo solve infertility, modern science has promoted assisted reproduction techniques such as in vitro fertilization, ovulation induction, and...
