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Interstitial Lung Abnormalities (ILA) and Pulmonary Fibrosis
Purpose of ReviewThis review identifies the similarities and differences between interstitial lung abnormalities (ILA) and pulmonary fibrosis in...
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Metabolomic insights into pulmonary fibrosis: a mendelian randomization study
BackgroundThis study leverages a two-sample Mendelian Randomization (MR) approach to explore the causal relationships between 1,400 metabolites and...
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NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin
BackgroundIdiopathic pulmonary fibrosis is a persistent disease of the lung interstitium for which there is no efficacious pharmacological therapy....
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Tuftelin1 drives experimental pulmonary fibrosis progression by facilitating stress fiber assembly
BackgroundIdiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease (ILD) with unknown etiology, characterized by sustained...
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Dexmedetomidine alleviates pulmonary fibrosis through the ADORA2B-Mediated MAPK signaling pathway
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronically progressive fibrotic pulmonary disease characterized by an uncertain etiology, a poor...
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Trigonelline hydrochloride attenuates silica-induced pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation
BackgroundSilicosis represents a paramount occupational health hazard globally, with its incidence, morbidity, and mortality on an upward trajectory,...
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Animal models of acute exacerbation of pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive scarring interstitial lung disease with an unknown cause. Some patients may experience...
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YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells
Paraquat (PQ) is a widely used herbicide and a common cause of poisoning that leads to pulmonary fibrosis with a high mortality rate. However, the...
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IL-11 system participates in pulmonary artery remodeling and hypertension in pulmonary fibrosis
BackgroundPulmonary hypertension (PH) associated to idiopathic pulmonary fibrosis (IPF) portends a poor prognosis. IL-11 has been implicated in...
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Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis
BackgroundFibrotic interstitial lung disease is often identified late due to non-specific symptoms, inadequate access to specialist care, and...
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Searching for airways biomarkers useful to identify progressive pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic and progressive disorder with unknown etiology. To date, the identification of new...
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Sirtuins and Cellular Senescence in Patients with Idiopathic Pulmonary Fibrosis and Systemic Autoimmune Disorders
The sirtuin family is a heterogeneous group of proteins that play a critical role in many cellular activities. Several degenerative diseases have...
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The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin
BackgroundAt present, the treatment options available for idiopathic pulmonary fibrosis are both limited and often come with severe side effects,...
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Assessment of lung deformation in patients with idiopathic pulmonary fibrosis with elastic registration technique on pulmonary three-dimensional ultrashort echo time MRI
ObjectiveTo assess lung deformation in patients with idiopathic pulmonary fibrosis (IPF) using with elastic registration algorithm applied to...
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CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis
COVID‐19 patients can develop clinical and histopathological features associated with fibrosis, but the pathogenesis of fibrosis remains poorly...
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Monoclonal enolase-1 blocking antibody ameliorates pulmonary inflammation and fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic fatal disease with limited therapeutic options. The infiltration of monocytes and...
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NR2F2 alleviates pulmonary fibrosis by inhibition of epithelial cell senescence
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fatal, and aging-associated interstitial lung disease with a poor prognosis and...
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A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with few effective therapeutic options. Recently, drug repositioning,...
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Relationship Between Esophageal Disease and Pulmonary Fibrosis
Esophageal disorders are prevalent among patients with chronic lung diseases, including idiopathic pulmonary fibrosis (IPF). Gastroesophageal reflux...
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Antifibrotic mechanism of avitinib in bleomycin-induced pulmonary fibrosis in mice
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by alveolar epithelial cell injury and lung...
