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Pulmonary Drug Delivery Systems: Material and Technological Advances
This book provides an insight into state-of-art developments in pulmonary drug delivery systems. It comprises several chapters covering a wide range...
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Inhaled drug delivery: a randomized study in intubated patients with healthy lungs
BackgroundThe administration technique for inhaled drug delivery during invasive ventilation remains debated. This study aimed to compare in vivo and...
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Novel Pulmonary Delivery of Drugs for the Management of Atrial Fibrillation
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, affecting approximately 335 million patients worldwide. Comprehensive...
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Preparation and evaluation of pirfenidone loaded chitosan nanoparticles pulmonary delivery for idiopathic pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic and fatal disorder caused by abnormal extracellular matrix deposition, which results in...
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Extracellular vesicle-mediated drug delivery in breast cancer theranostics
Breast cancer (BC) continues to be a significant global challenge due to drug resistance and severe side effects. The increasing prevalence is...
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Alzheimerās disease and drug delivery across the bloodābrain barrier: approaches and challenges
Alzheimer's disease (AD) is a diverse disease with a complex pathophysiology. The presence of extracellular Ī²-amyloid deposition as neuritic plaques...
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Pharmacokinetics of nanoparticles: current knowledge, future directions and its implications in drug delivery
BackgroundNanoparticles have emerged as a viable biological candidate with the possibility to be employed as drug carriers. They acquire high...
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Ionizable drug delivery systems for efficient and selective gene therapy
Gene therapy has shown great potential to treat various diseases by repairing the abnormal gene function. However, a great challenge in bringing the...
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Effect of pressures and type of ventilation on aerosol delivery to chronic obstructive pulmonary disease patients
BackgroundContinuous Positive Airway Pressure (CPAP), BiPhasic Positive Airway Pressure (BiPAP), and high flow nasal cannula (HFNC) show some...
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Toxicology of Nanoparticles in Drug Delivery
Nanoparticles have revolutionized biomedicine especially in the field of drug delivery due to their intriguing properties such as systemic stability,...
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A Case report of a continuous ambulatory drug delivery (CADD) pump to deliver opioid agonist treatment in an acute care setting
BackgroundPeople with substance use disorder are at risk of complications of drug use and frequent hospitalization and may continue to use substances...
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Meeting the challenges of NTM-PD from the perspective of the organism and the disease process: innovations in drug development and delivery
Non-tuberculous mycobacterial pulmonary disease (NTM-PD) poses a substantial patient, healthcare, and economic burden. Managing NTM-PD remains...
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Nintedanib-loaded exosomes from adipose-derived stem cells inhibit pulmonary fibrosis induced by bleomycin
BackgroundPulmonary fibrosis (PF) is a progressive lung disorder with a high mortality rate; its therapy remains limited due to the inefficiency of...
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Emergency right lower lobectomy for severe pulmonary abscess in a pregnant woman at the 25th week of gestation: a case report
BackgroundPulmonary abscess is a severe infection commonly seen in patients with chronic obstructive pulmonary disease, interstitial pneumonia,...
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Pulmonary hypertension
Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to elevated pressures within the pulmonary arteries. Five...
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Intranasal administration enhances size-dependent pulmonary phagocytic uptake of poly(lactic-co-glycolic acid) nanoparticles
BackgroundNanoparticles exhibit distinct behaviours within the body, depending on their physicochemical properties and administration routes....
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Acid ceramidase gene therapy ameliorates pulmonary arterial hypertension with right heart dysfunction
BackgroundUp-regulation of ceramides in pulmonary hypertension (PH), contributing to perturbations in sphingolipid homeostasis and the transition of...
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Future Perspectives of Pulmonary Arterial Hypertension: A Review of Novel Pipeline Treatments and Indications
Pulmonary arterial hypertension is characterized by elevated blood pressure and pathological changes in the pulmonary arterioles, leading to the...
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Embolization treatment of right pulmonary artery agenisis with patent ductus arteriosus causing pulmonary hypertension and hemoptysis: a case report and literature review
As the pediatric patient with right pulmonary artery agenesis (PAA) matured, she progressively presented symptoms of pulmonary hypertension and...
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Aerosolised micro and nanoparticle: formulation and delivery method for lung imaging
PurposeThe application of contrast and tracing agents is essential for lung imaging, as indicated by the wide use in recent decades and the discovery...
