Search
Search Results
-
Segmentation of patients with small cell lung cancer into responders and non-responders using the optimal cross-validation technique
BackgroundThe timing of treating cancer patients is an essential factor in the efficacy of treatment. So, patients who will not respond to current...
-
Ultra-low–dose and very-low–dose Lupron downregulation protocols for poor responders based on POSEIDON group 3 and 4 classifications
PurposeThe objective of this study was to assess if very-low–dose Lupron (VLDL) and ultra-low–dose Lupron (ULDL) protocols can have comparable cycle...
-
Efficacy of rituximab and risk factors for poor prognosis in patients with childhood-onset steroid-resistant nephrotic syndrome: a multicenter study
BackgroundThe efficacy of rituximab in steroid-resistant nephrotic syndrome (SRNS) is controversial. We previously reported that rituximab in...
-
Factors influencing poor response to type 2 targeted therapies in severe asthma: a retrospective cohort study
BackgroundA significant breakthrough has been made in treating severe asthma, with the recognition of various asthma phenotypes and an updated...
-
Exceptional Responders in Gynecologic Oncology: A case series and review of literature
The majority of patients with advanced metastatic gynecological malignancies are difficult to treat, yet few patients respond exceptionally well to...
-
Immunophenoty** of peripheral blood in NSCLC patients discriminates responders to immune checkpoint inhibitors
PurposeImmune checkpoint inhibitors (ICIs) dramatically changed the prognosis of patients with NSCLC. Unfortunately, a reliable predictive biomarker...
-
Early biochemical and radiographic response after one cycle of [177Lu]Lu-PSMA I&T radioligand therapy in metastatic castration-resistant prostate cancer patients
PurposeThe aim of this study was to investigate very early radiographic PSMA PET response after one cycle of [ 177 Lu]Lu-PSMA I&T radioligand therapy...
-
A prospective randomized trial comparing corifollitropin-α late-start (day 4) versus standard administration (day 2) in expected poor, normal, and high responders undergoing controlled ovarian stimulation for IVF
ObjectiveTo assess whether corifollitropin-α (CFα) late-start administration (day 4) and standard administration (day 2) can obtain similar oocyte...
-
Potential Predictive Immune and Metabolic Biomarkers of Tumor Microenvironment Regarding Pathological and Clinical Response in Esophageal Cancer After Neoadjuvant Chemoradiotherapy: A Systematic Review
IntroductionThe tumor microenvironment (TME) plays a crucial role in therapy response and modulation of immunologic surveillance. Adjuvant...
-
-
Presence of peritumoral edema on T2w MRI: a poor non-invasive prognostic marker in breast cancer patients
BackgroundThe purpose of the study was to assess the correlation between peritumoral edema (PE) seen on magnetic resonance imaging (MRI) in breast...
-
In situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy
In this study, we investigated the metabolic alterations associated with clinical response to chemotherapy in patients with ovarian cancer. Pre- and...
-
Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma
PurposeFew studies have reported the impact of chemoradiotherapy (CRT) on the objective response of patients with locally advanced unresectable...
-
Efficacy and cost analysis of eltrombopag in thrombocytopenia and poor graft function post allogeneic hematopoietic cell transplantation
Eltrombopag has shown efficacy in the treatment of thrombocytopenia and poor graft function (PGF) after allogeneic hematopoietic cell transplantation...
-
Myelomonocytic and monocytic acute myeloid leukemia demonstrate comparable poor outcomes with venetoclax-based treatment: a monocentric real-world study
Venetoclax (VEN), a BCL-2 inhibitor, has transformed treatment strategies for elderly and unfit acute myeloid leukemia (AML) patients by...
-
Early response assessment to targeted therapy in metastatic clear cell renal cancer using 68Ga-PSMA-11 PET/CT and comparison with CECT: a feasibility study
PurposeContrast-enhanced computed tomography (CECT) underestimates the response to targeted therapy in metastatic renal cell cancer (mRCC) using...
-
Soluble interleukin-2 receptor as a predictive biomarker for poor efficacy of combination treatment with anti-PD-1/PD-L1 antibodies and chemotherapy in non-small cell lung cancer patients
Soluble interleukin-2 receptor (sIL-2R) suppresses effector T-cells. Few studies have assessed serum sIL-2R in patients receiving immunotherapy. We...
-
Diaphragmatic excursion is correlated with the improvement in exercise tolerance after pulmonary rehabilitation in patients with chronic obstructive pulmonary disease
BackgroundIn patients with chronic obstructive pulmonary disease (COPD), the maximum level of diaphragm excursion (DE max ) is correlated with dynamic...
-
GH and IGF-I levels and tumor shrinkage in response to first generation somatostatin receptor ligands in acromegaly: a comparative study between two reference centers for pituitary diseases in Brazil
PurposeTo compare biochemical and tumor response rates between two reference centers for pituitary diseases in Brazil after primary and adjuvant...
-
Pattern of disease progression during third-line or later chemotherapy with nivolumab associated with poor prognosis in advanced gastric cancer: a multicenter retrospective study in Japan
BackgroundAccelerated tumor growth during immunotherapy in pre-existing measurable lesions, hyperprogressive disease (HPD), has been reported....
