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Does structural form matter? A comparative analysis of pooled procurement mechanisms for health commodities
IntroductionPooled procurement can be seen as a collaboration initiative of buyers. Such mechanisms have received increased attention during the...
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Pooled prevalences of obstructive sleep apnea and heart failure: a systematic review and meta-analysis
Obstructive sleep apnea (OSA) is a disease with intermittent hypoxemia during sleep. It has been shown that OSA is related to several cardiovascular...
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Postoperative stereotactic radiosurgery for intracranial solitary fibrous tumors: systematic review and pooled quantitative analysis
BackgroundIntracranial solitary fibrous tumors (SFTs), formerly hemangiopericytomas (HPCs), are rare, aggressive dural-based mesenchymal tumors....
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Outcome of brain metastases from adrenocortical carcinoma: a pooled analysis
PurposeBrain metastases rarely complicate the natural history of patients with adrenocortical carcinoma (ACC). No information is available regarding...
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Association of moyamoya vasculopathy with autoimmune disease: a systematic review and pooled analysis
Despite more than six decades of extensive research, the etiology of moyamoya disease (MMD) remains unknown. Inflammatory or autoimmune (AI)...
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Pooled prevalence of depressive symptoms among medical students: an individual participant data meta-analysis
BackgroundThe methodological choice of aggregated estimates for meta-analysis may be notable for some common drawbacks, including variations in the...
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Efficacy and safety of osimertinib for leptomeningeal metastases from EGFR-mutant non-small cell lung cancer: a pooled analysis
BackgroundThe aim of this study was to evaluate the efficacy and safety of osimertinib for the treatment of leptomeningeal metastases (LM) from...
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The addition of rituximab to chemotherapy improves overall survival in mantle cell lymphoma—a pooled trials analysis
Mantle cell lymphoma (MCL) is a distinct subtype of B-cell lymphoma and commonly used induction immunochemotherapies include the anti-CD20 antibody...
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Safety and tolerability of atogepant for the preventive treatment of migraine: a post hoc analysis of pooled data from four clinical trials
BackgroundConventional, non-specific preventive migraine treatments often demonstrate low rates of treatment persistence due to poor efficacy or...
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Validation and Application of Thresholds to Define Meaningful Change in Vasomotor Symptoms Frequency: Analysis of Pooled SKYLIGHT 1 and 2 Data
IntroductionVasomotor symptoms (VMS), the characteristic symptoms of menopausal transition, are often the primary reason women seek treatment....
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Internalised stigma among people with mental illness in Africa, pooled effect estimates and subgroup analysis on each domain: systematic review and meta-analysis
BackgroundInternalisation of stigma occurs when people with a stigmatised attribute, such as a mental illness, supress negative but accepted societal...
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Secukinumab in Pediatric Patients with Plaque Psoriasis: Pooled Safety Analysis from Two Phase 3 Randomized Clinical Trials
BackgroundPlaque psoriasis affects ~ 1% of the pediatric population, negatively impacting quality of life. The efficacy and safety of secukinumab in...
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Neuromuscular diseases associated with COVID-19 vaccines: a systematic review and pooled analysis of 258 patients
BackgroundNeuromuscular diseases (NMD) emerged as one of the main side effects of the COVID-19 vaccination. We pooled and summarized the evidence on...
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Effectiveness and Tolerability of 12-Month Brivaracetam in the Real World: EXPERIENCE, an International Pooled Analysis of Individual Patient Records
Background and ObjectiveReal-world evidence studies of brivaracetam (BRV) have been restricted in scope, location, and patient numbers. The objective...
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Sociodemographic risk factors for the persistence of harmful alcohol use: a pooled analysis of prospective cohort studies
PurposePrevious research suggests several sociodemographic risk factors for the persistence of harmful alcohol use. However, the evidence is limited...
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Impact of robotic total mesorectal excision upon pathology metrics in overweight males with low rectal cancer: a pooled analysis of 836 cases
The aim of this pooled analysis was to evaluate the impact of robotic total mesorectal excision (TME) on pathology metrics in Male Overweight...
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Oncoplastic versus conventional breast-conserving surgery in breast cancer: a pooled analysis of 6941 female patients
BackgroundBreast cancer is the most prevalent cancer in women. In the past few years, surgical interventions for breast cancer have experienced...
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Pooled prevalence of lymphopenia in all-cause hospitalisations and association with infection: a systematic review and meta-analysis
BackgroundLymphopenia is defined as a decrease below normal value (often 1.0 x 10 9 cells/L) of blood circulating lymphocyte count. In the general...
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Safety of nivolumab monotherapy in five cancer types: pooled analysis of post-marketing surveillance in Japan
BackgroundNivolumab has been approved for treating ≥ 10 cancer types. However, there is limited information on the incidence of rare, but potentially...
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Topical cyclosporine A cationic ophthalmic emulsion in paediatric vernal keratoconjunctivitis: pooled analysis of randomised NOVATIVE and VEKTIS trials
Background/ObjectivesCyclosporine A cationic ophthalmic emulsion (CsA CE) was evaluated in paediatric and adolescent patients with vernal...
