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Changes in glutamic oxaloacetic transaminase 2 during rat physiological and pathological cardiomyocyte hypertrophy
BackgroundPhysiological and pathological cardiomyocyte hypertrophy are important pathophysiological processes of adult congenital heart...
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Short-Term Metabolic Changes and Their Physiological Mediators in the Roux-en-Y Gastric Bypass Bariatric Surgery
BackgroundThe Roux-en-Y gastric bypass (RYGB) is a common bariatric surgery to treat obesity. Its metabolic consequences are favourable and long-term...
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Assessment of pulmonary physiological changes caused by aging, cigarette smoking, and COPD with hyperpolarized 129Xe magnetic resonance
ObjectiveTo comprehensively assess the impact of aging, cigarette smoking, and chronic obstructive pulmonary disease (COPD) on pulmonary physiology...
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Interlink Between Physiological and Biomechanical Changes in the Swim-to-Cycle Transition in Triathlon Events: A Narrative Review
Triathlon is a multisport composed of swim, cycle, and run segments and two transition periods. The swim-to-cycle transition is considered a critical...
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Dynamic Bayesian network for predicting physiological changes, organ dysfunctions and mortality risk in critical trauma patients
BackgroundCritical trauma patients are particularly prone to increased mortality risk; hence, an accurate prediction of their conditions enables...
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Oscillometry of the respiratory system in Parkinson's disease: physiological changes and diagnostic use
BackgroundLung function analysis in Parkinson's disease (PD) is often difficult due to the demand for adequate forced expiratory maneuvers....
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Repository Describing the Anatomical, Physiological, and Biological Changes in an Obese Population to Inform Physiologically Based Pharmacokinetic Models
BackgroundObesity is associated with physiological changes that can affect drug pharmacokinetics. Obese individuals are underrepresented in clinical...
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Physiological and mental health changes in cancer patients during the COVID-19 state of emergency
BackgroundsDue to the COVID-19 pandemic that we are currently facing, many governments across the world have declared a state of emergency and even...
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Time-dependent pathobiological and physiological changes of implanted vein grafts in a canine model
Although autologous vein grafting is essential, the high vein failure rate and specific clinical interventions are not clear, so a potential...
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Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system
Mechanosensitive Piezo ion channels were first reported in 2010 in a mouse neuroblastoma cell line, opening up a new field for studying the...
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Bone Changes in Chronic Rhinosinusitis: Pathological or Physiological?
Bone remodelling is a normal physiological process which occurs in all bones. Hence bone changes should also be detected in undiseased or minimally...
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Physiological confounders of renal blood flow measurement
ObjectivesRenal blood flow (RBF) is controlled by a number of physiological factors that can contribute to the variability of its measurement. The...
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Women at Altitude: Sex-Related Physiological Responses to Exercise in Hypoxia
Sex differences in physiological responses to various stressors, including exercise, have been well documented. However, the specific impact of these...
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Early adverse physiological event detection using commercial wearables: challenges and opportunities
Data from commercial off-the-shelf (COTS) wearables leveraged with machine learning algorithms provide an unprecedented potential for the early...
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Physiological biodistribution on Ga68-PSMA PET/CT and the factors effecting biodistribution
AimThe study aims to determine the physiological and pathophysiological distribution of the radiopharmaceutical (Ga 68 -PSMA-617) and investigate...
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Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs
Background and ObjectiveAs a result of changes in physiology during pregnancy, the pharmacokinetics (PK) of drugs can be altered. It is unclear...
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Immune cells in adipose tissue microenvironment under physiological and obese conditions
PurposeThis review will focus on the immune cells in adipose tissue microenvironment and their regulatory roles in metabolic homeostasis of adipose...
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Challenges and prospects of visual contactless physiological monitoring in clinical study
The monitoring of physiological parameters is a crucial topic in promoting human health and an indispensable approach for assessing physiological...
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Obesity-induced and weight-loss-induced physiological factors affecting weight regain
Weight regain after successful weight loss resulting from lifestyle interventions is a major challenge in the management of overweight and obesity....