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1. PET imaging and quantification of small animals using a clinical SiPM-based camera

   Background

   Small-animal PET imaging is an important tool in preclinical oncology. This study evaluated the ability of a clinical SiPM-PET camera to...

   Cédric Desmonts, Charline Lasnon, ... Nicolas Aide in EJNMMI Physics

   Article Open access 07 October 2023
   

2. Ultra-low-dose CT for attenuation correction: dose savings and effect on PET quantification for protocols with and without tin filter

   Background

   Ultra-low-dose (ULD) computed tomography (CT) scans should be used when CT is performed only for attenuation correction (AC) of positron...

   Natalie Anne Bebbington, Kenneth Boye Christensen, ... Paw Christian Holdgaard in EJNMMI Physics

   Article Open access 20 October 2023
   

3. Validation of cardiac image-derived input functions for functional PET quantification

   Purpose

   Functional PET (fPET) is a novel technique for studying dynamic changes in brain metabolism and neurotransmitter signaling. Accurate...

   Murray Bruce Reed, Patricia Anna Handschuh, ... Andreas Hahn in European Journal of Nuclear Medicine and Molecular Imaging

   Article Open access 27 April 2024
   

4. Non-invasive quantification of ¹⁸F-florbetaben with total-body EXPLORER PET

   Background

   Kinetic modeling of ¹⁸ F-florbetaben provides important quantification of brain amyloid deposition in research and clinical settings but...

   Emily Nicole Holy, Elizabeth Li, ... Audrey P. Fan in EJNMMI Research

   Article Open access 16 April 2024
   

5. Investigation of PET image quality with acquisition time/bed and enhancement of lesion quantification accuracy through deep progressive learning

   Objective

   To improve the PET image quality by a deep progressive learning (DPL) reconstruction algorithm and evaluate the DPL performance in lesion...

   Hongxing Yang, Shihao Chen, ... Shaoli Song in EJNMMI Physics

   Article Open access 10 January 2024
   

6. Assessment of [¹⁸F]PI-2620 Tau-PET Quantification via Non-Invasive Automatized Image Derived Input Function

   Purpose

   [ ¹⁸ F]PI-2620 positron emission tomography (PET) detects misfolded tau in progressive supranuclear palsy (PSP) and Alzheimer’s disease (AD)....

   Maria Meindl, Artem Zatcepin, ... Matthias Brendel in European Journal of Nuclear Medicine and Molecular Imaging

   Article Open access 08 May 2024
   

7. Spatial normalization and quantification approaches of PET imaging for neurological disorders

   Quantification approaches of positron emission tomography (PET) imaging provide user-independent evaluation of pathophysiological processes in living...

   Teng Zhang, Shuang Wu, ... Mei Tian in European Journal of Nuclear Medicine and Molecular Imaging

   Article 28 May 2022
   

8. Advances in Digital PET Technology and Its Potential Impact on Myocardial Perfusion and Blood Flow Quantification

   Purpose of Review

   In this review, we explore the development of digital PET scanners and describe the mechanism by which they work. We dive into some...

   Fares Alahdab, Mahmoud Al Rifai, ... Mouaz H. Al-Mallah in Current Cardiology Reports

   Article 24 February 2023
   

9. AI-based quantification of whole-body tumour burden on somatostatin receptor PET/CT

   Background

   Segmenting the whole-body somatostatin receptor-expressing tumour volume (SRETVwb) on positron emission tomography/computed tomography...

   Anni Gålne, Olof Enqvist, ... Elin Trägårdh in European Journal of Hybrid Imaging

   Article Open access 07 August 2023
   

10. Automated quantification of PET/CT skeletal tumor burden in prostate cancer using artificial intelligence: The PET index

    Purpose

    Consistent assessment of bone metastases is crucial for patient management and clinical trials in prostate cancer (PCa). We aimed to develop a...

    Sarah Lindgren Belal, Måns Larsson, ... Elin Trägårdh in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 18 January 2023
    

11. 3D-printed dual holder system for simultaneous rat PET scanning: design and influence on quantification

    Background

    The low throughout of small animal positron emission tomography (PET) images acquisitions represents a substantial limitation. The aims of...

    Caroline Bouillot, Sébastien Daligault, ... Luc Zimmer in EJNMMI Research

    Article Open access 07 September 2023
    

12. Clinical Performance Evaluation of an Artificial Intelligence-Powered Amyloid Brain PET Quantification Method

    Purpose

    This study assesses the clinical performance of BTXBrain-Amyloid, an artificial intelligence-powered software for quantifying amyloid uptake...

    Seung Kwan Kang, Mina Heo, ... Jae Sung Lee in Nuclear Medicine and Molecular Imaging

    Article Open access 02 May 2024
    

13. Impact of gadolinium-based contrast agents on attenuation correction and tracer quantification in neuroendocrine malignancies in [⁶⁸Ga]-DOTATOC PET/MRI

    Objectives

    To investigate the influence of Gadolinium-based contrast agents (CA) on MR-based attenuation correction (MRAC) in evaluating target...

    Aleksandar Milosevic, Michal Chodyla, ... Benedikt M. Schaarschmidt in Clinical and Translational Imaging

    Article 25 April 2024
    

14. Feasibility of ¹⁸F-florzolotau quantification in patients with Alzheimer’s disease based on an MRI-free tau PET template

    Objectives

    Quantification of tau accumulation using positron emission tomography (PET) is critical for the diagnosis of Alzheimer’s disease (AD). This...

    Jiaying Lu, Zizhao Ju, ... Chuantao Zuo in European Radiology

    Article 26 April 2023
    

15. Motion correction and its impact on quantification in dynamic total-body 18F-fluorodeoxyglucose PET

    Background

    The total-body positron emission tomography (PET) scanner provides an unprecedented opportunity to scan the whole body simultaneously,...

    Tao Sun, Ya** Wu, ... Meiyun Wang in EJNMMI Physics

    Article Open access 14 September 2022
    

16. Impact of brain segmentation methods on regional metabolism quantification in ¹⁸F-FDG PET/MR analysis

    Background

    Accurate analysis of quantitative PET data plays a crucial role in studying small, specific brain structures. The integration of PET and...

    Yi Shan, Shao-zhen Yan, ... Jie Lu in EJNMMI Research

    Article Open access 05 September 2023
    

17. Quantification of amyloid PET for future clinical use: a state-of-the-art review

    Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer’s disease (AD) pathogenesis. The overall load and spatial...

    Hugh G. Pemberton, Lyduine E. Collij, ... Gill Farrar in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 07 April 2022
    

18. 2-[¹⁸F]FDG PET-based quantification of lymph node metabolic heterogeneity for predicting lymph node metastasis in patients with colorectal cancer

    Background and purpose

    The pre-surgical estimation of lymph node (LN) metastasis in colorectal cancer (CRC) poses a significant diagnostic...

    Lian Xu, Gan Huang, ... Ruohua Chen in European Journal of Nuclear Medicine and Molecular Imaging

    Article 27 December 2023
    

19. The effect of Q.Clear reconstruction on quantification and spatial resolution of 18F-FDG PET in simultaneous PET/MR

    Background

    Q.Clear is a block sequential regularized expectation maximization penalized-likelihood reconstruction algorithm for Positron Emission...

    Defeng Tian, Hongwei Yang, ... Jie Lu in EJNMMI Physics

    Article Open access 10 January 2022
    

20. Comparison of protocols with respiratory-gated (4D) motion compensation in PET/CT: open-source package for quantification of phantom image quality

    Background

    Patient’s breathing affects the quality of chest images acquired with positron emission tomography/computed tomography (PET/CT) studies....

    Andrea Martinez-Movilla, Michael Mix, ... Montserrat Carles in EJNMMI Physics

    Article Open access 17 November 2022