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Timing to Surgery and Lymph Node Upstaging in Gastric Cancer: An NCDB Analysis
BackgroundPrior studies have shown tumor specificity on the impact of longer time interval from diagnosis to surgery, however in gastric cancer (GC)...
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Differential response to neoadjuvant endocrine therapy for Black/African American and White women in NCDB
PurposeCompared to White women, there are higher mortality rates in Black/African American (BAA) women with hormone receptor-positive breast cancer...
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Neoadjuvant systemic therapy in geriatric breast cancer patients: a National Cancer Database (NCDB) analysis
PurposeNeoadjuvant systemic therapy (NAST) can be an effective treatment option for patients with HER2 + or triple negative breast cancer (TNBC)....
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Nationwide Analysis of Locoregional Management for Ductal Carcinoma In Situ in Males: An NCDB Analysis of the Surgical Approach to DCIS in Males
BackgroundLimited data exist regarding the optimal locoregional approach for males with ductal carcinoma in situ (DCIS). This study examined trends...
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Surgical Treatment of Patients with Poorly Differentiated Pancreatic Neuroendocrine Carcinoma: An NCDB Analysis
BackgroundConsensus guidelines discourage resection of poorly differentiated pancreatic neuroendocrine carcinoma (panNEC) given its association with...
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Outcomes of Local Excision Compared to Radical Excision of Rectal Gastrointestinal Stromal Tumors: A Propensity-Score Matched Analysis of the NCDB
BackgroundGastrointestinal stromal tumors (GISTs) account for <1% of gastrointestinal cancers. The present study aimed to assess the outcomes of...
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The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB)
PurposePrimary site surgery for metastatic breast cancer improves local control but does not impact overall survival. Whether histologic subtype...
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Colorectal cancer in the 45-to-50 age group in the United States: a National Cancer Database (NCDB) analysis
BackgroundAmid increasing awareness of early-onset colorectal cancer (CRC), guidelines in the United States (US) recently lowered the recommended...
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Impact of Metastasectomy and Aggressive Local Therapy in Newly Diagnosed Metastatic Soft Tissue Sarcoma: An Analysis of the NCDB
BackgroundThe optimal management of patients with stage IV soft tissue sarcoma of the extremity (STSE) with distant metastases at diagnosis is...
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Surgical Management of the Axilla of HER2+ Breast Cancer in the Z1071 Era: A Propensity-Score-Matched Analysis of the NCDB
IntroductionWe aim to analyze survival outcomes for sentinel lymph node biopsy (SLNB) versus axillary lymph node dissection (ALND) in human epidermal...
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Analysis of Post-operative Adjuvant Chemotherapy Versus Adjuvant Chemoradiation Therapy Outcomes in Non-metastatic Cholangiocarcinoma: an NCDB Review
BackgroundEach year, approximately 8000 cases of cholangiocarcinoma are recorded in the USA. Surgical resection is considered to be the only curative...
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Role of thoracic radiation in extensive stage small cell lung cancer: a NCDB analysis
Prognosis of extensive stage small cell lung cancer (ES-SCLC) remains poor. Previous randomized trials suggested consolidation chest radiation (CXRT)...
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Effectiveness of a Short Duration of Neoadjuvant Endocrine Therapy in Patients with HR+ Breast Cancer—An NCDB Analysis (2004–2016)
BackgroundNational medical/surgical organizations have recommended the use of neoadjuvant endocrine therapy (NET) to bridge surgery delay of weeks to...
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Trends in neoadjuvant chemotherapy versus surgery-first in stage I HER2-positive breast cancer patients in the National Cancer DataBase (NCDB)
BackgroundNeoadjuvant chemotherapy (NAC) is the standard of care for locally advanced HER2 + breast cancer (BC). Optimal sequencing of treatment (NAC...
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Prognosis and Chemotherapy Use in Breast Cancer Patients with Multiple Lymphatic Micrometastases: An NCDB Analysis
BackgroundThe number of involved lymph nodes negatively affects prognosis in breast cancer patients. Nevertheless, current staging and treatment...
