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1. The prognostic role of metabolic tumor burden in ¹⁸F-FDG PET/CT in the primary staging of rectal cancers

   Introduction

   The prognostic value of FDG PET/CT metabolic tumor burden has been established in various solid tumors, but its significance in the...

   Juliano S. Fonseca, Maria Carolina S. Mendes, ... Elba Etchebehere in Clinical and Translational Imaging

   Article 04 March 2024
   

2. Influence of metabolic tumor burden on reference tissues’ standardized uptake values in ¹⁸F-FDG PET/CT sequential imaging

   Background

   Extremely hypermetabolic neoplastic tissues have been hypothesized to act as a “sink” reducing the amount of radiopharmaceutical available...

   Ahmed Badawy, Marwa Mohamed Maamoun, ... Hoda Anwar in Egyptian Journal of Radiology and Nuclear Medicine

   Article Open access 17 November 2023
   

3. Does gamma-glutamyltransferase correlate with liver tumor burden in neuroendocrine tumors?

   Purpose

   In patients with neuroendocrine tumors (NETs) and liver metastases, increased gamma-glutamyltransferase (GGT) is commonly assumed as an...

   Benjamin Christopher Schmidt, Miriam Theresa Leiderer, ... Jörg Schrader in Endocrine

   Article Open access 28 September 2023
   

4. Prognostic value of visual IMPeTUs criteria and metabolic tumor burden at baseline [¹⁸F]FDG PET/CT in patients with newly diagnosed multiple myeloma

   Background

   2-[ ¹⁸ F]fluoro-2-deoxy-D-glucose ([ ¹⁸ F]FDG) positron emission tomography combined with low-dose computed tomography (PET/CT) can be used at...

   Silvano Marchiori, François Cousin, ... Nadia Withofs in EJNMMI Research

   Article Open access 28 May 2024
   

5. Whole-body tumor burden in PET/CT expert review

   Introduction

   PET/CT whole-body tumor burden (WBTB), as a measure for overall burden of cancer, has been shown bear a strong correlation with...

   Dihego F. Santos, Maria Emilia Takahashi, ... Elba Etchebehere in Clinical and Translational Imaging

   Article 05 August 2022
   

6. Volumetric parameters of the primary tumor and whole-body tumor burden derived from baseline ¹⁸F-FDG PET/CT can predict overall survival in non-small cell lung cancer patients: initial results from a single institution

   Background

   Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are volumetric parameters derived from ¹⁸ F-FDG PET/CT, suggested to have a...

   Hemat A. Mahmoud, Walaa Oteify, ... Nesreen Mekkawy in European Journal of Hybrid Imaging

   Article Open access 28 December 2022
   

7. NF2: An underestimated player in cancer metabolic reprogramming and tumor immunity

   Neurofibromatosis type 2 ( NF2 ) is a tumor suppressor gene implicated in various tumors, including mesothelioma, schwannomas, and meningioma. As a...

   Duo Xu, Shiyuan Yin, Yongqian Shu in npj Precision Oncology

   Article Open access 15 June 2024
   

8. Prognostic value of metabolic tumor volume of extranodal involvement in diffuse large B cell lymphoma

   Extranodal involvement predicts poor outcomes of diffuse large B cell lymphoma (DLBCL), but the impact of the metabolic tumor burden (MTV) of...

   Kana Oiwa, Kei Fujita, ... Takahiro Yamauchi in Annals of Hematology

   Article Open access 23 March 2023
   

9. Metabolic hallmarks of natural killer cells in the tumor microenvironment and implications in cancer immunotherapy

   Natural killer (NK) cells belong to the early responder group against cancerous cells and viral infection. Emerging evidence reveals that distinct...

   Yuqing Yang, Lin Chen, ... Shengtao Zhou in Oncogene

   Article 06 December 2022
   

10. High baseline total lesion glycolysis predicts early progression of disease within 24 months in patients with high-tumor-burden follicular lymphoma

    Despite the introduction of rituximab-containing regimens, approximately 20% of patients with follicular lymphoma (FL) still experience progression...

    Wataru Kuroki, Akihiro Kitadate, ... Naoto Takahashi in International Journal of Hematology

    Article 20 July 2022
    

11. TGF-β signaling in the tumor metabolic microenvironment and targeted therapies

    Transforming growth factor-β (TGF-β) signaling has a paradoxical role in cancer progression, and it acts as a tumor suppressor in the early stages...

    Xueke Shi, ** Yang, ... Hongmei Zhou in Journal of Hematology & Oncology

    Article Open access 17 September 2022
    

12. Tumor and metastatic lymph nodes metabolic activity on ¹⁸F-FDG-PET/CT to predict progression-free survival in locally advanced cervical cancer

    Objective

    The present study investigated the predictive diseases progression value of preoperative fluorodeoxyglucose (FDG) positron emission...

    **ling Song, Weiqiang Pang, ... Linfa Li in Abdominal Radiology

    Article 01 February 2024
    

13. In situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy

    In this study, we investigated the metabolic alterations associated with clinical response to chemotherapy in patients with ovarian cancer. Pre- and...

    Sara Corvigno, Sunil Badal, ... Anil K. Sood in npj Precision Oncology

    Article Open access 03 November 2023
    

14. The remodeling of metabolic brain pattern in patients with extracranial diffuse large B-cell lymphoma

    Background

    Owing to the advances in diagnosis and therapy, survival or remission rates for lymphoma have improved prominently. Apart from the...

    Junyi Liu, Ming Tang, ... Yuankai Zhu in EJNMMI Research

    Article Open access 30 October 2023
    

15. Tumor mutational burden presents limiting effects on predicting the efficacy of immune checkpoint inhibitors and prognostic assessment in adrenocortical carcinoma

    Background

    Adrenocortical carcinoma (ACC) is a highly malignant urologic cancer and tends to metastasize. Although immune checkpoint inhibitors (ICIs)...

    Fangshi Xu, Yibing Guan, ... Bin-Cheng Ren in BMC Endocrine Disorders

    Article Open access 14 May 2022
    

16. TMTV-Net: fully automated total metabolic tumor volume segmentation in lymphoma PET/CT images — a multi-center generalizability analysis

    Purpose

    Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In...

    Fereshteh Yousefirizi, Ivan S. Klyuzhin, ... Arman Rahmim in European Journal of Nuclear Medicine and Molecular Imaging

    Article 08 February 2024
    

17. Challenges in chimeric antigen receptor-T cell product administration in a high tumor-burden elderly patient with mantle-cell lymphoma

    Umberto Pizzano, G. Facchin, ... F. Patriarca in Annals of Hematology

    Article 26 June 2024
    

18. Whole-tumoral metabolic heterogeneity in ¹⁸F-FDG PET/CT is a novel prognostic marker for neuroblastoma

    Background

    Neuroblastoma (NB) is a highly heterogeneous tumor, and more than half of newly diagnosed NB are associated with extensive metastases....

    Jun Liu, Qinghua Ren, ... Wei Wang in Cancer Imaging

    Article Open access 11 June 2024
    

19. Baseline total metabolic tumor volume (TMTV) application in Hodgkin lymphoma: a review article

    Introduction

    Functional metabolic imaging with 18 F-fluorodeoxyglucose positron emission tomography combined with computed tomography (PET/CT) is...

    Carolina Cristina Pellegrino Feres, Rafael Fernandes Nunes, ... Guilherme Fleury Perini in Clinical and Translational Imaging

    Article 02 February 2022
    

20. Lipid metabolic vulnerabilities of multiple myeloma

    Multiple myeloma (MM) is the second most common hematological malignancy worldwide, characterized by abnormal proliferation of malignant plasma cells...

    Roberta Torcasio, Maria Eugenia Gallo Cantafio, ... Nicola Amodio in Clinical and Experimental Medicine

    Article Open access 28 August 2023