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Efficacy and safety of ciprofol versus propofol for induction and maintenance of general anesthesia: a systematic review and meta-analysis
BackgroundPropofol has been the gold standard for anesthesia induction and maintenance due to its rapid onset and favorable pharmacokinetic...
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Matching-Adjusted Indirect Comparison of the Long-Term Efficacy Maintenance and Adverse Event Rates of Lebrikizumab versus Dupilumab in Moderate-to-Severe Atopic Dermatitis
IntroductionLebrikizumab and dupilumab are monoclonal antibodies approved for treating moderate-to-severe atopic dermatitis (AD). Both have...
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Relative efficacy and safety of calcineurin inhibitor, mycophenolate mofetil, and azathioprine as maintenance therapies for lupus nephritis: a network meta-analysis
ObjectiveThis study aimed to assess the relative efficacy and safety of calcineurin inhibitor (CNI), mycophenolate mofetil (MMF), and azathioprine...
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Comparative Efficacy of Subcutaneous and Intravenous Infliximab and Vedolizumab for Maintenance Treatment of TNF-naive Adult Patients with Inflammatory Bowel Disease: A Systematic Literature Review and Network Meta-analysis
BackgroundInfliximab and vedolizumab are widely used to treat Crohn’s disease (CD) and ulcerative colitis (UC).
AimsThis systematic review and...
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Clinical efficacy of the fourth dose of the BNT162b2 vaccine in maintenance dialysis patients
Background and objectivesHighly effective vaccines against severe acute respiratory syndrome virus 2 have been developed and administered worldwide....
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Veliparib with frontline chemotherapy and as maintenance in Japanese women with ovarian cancer: a subanalysis of efficacy, safety, and antiemetic use in the phase 3 VELIA trial
BackgroundThe phase 3 VELIA trial evaluated veliparib with carboplatin/paclitaxel and as maintenance in patients with high-grade serous ovarian...
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Efficacy and Safety of Niraparib as First-Line Maintenance Treatment for Patients with Advanced Ovarian Cancer: Real-World Data from a Multicenter Study in China
BackgroundPoly (ADP-ribose) polymerase (PARP) inhibitors are a new maintenance therapy option for patients with ovarian cancer (OC).
Objective ...
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Efficacy and safety of olaparib maintenance monotherapy for Japanese patients with platinum-sensitive relapsed ovarian, fallopian tube, and primary peritoneal cancer
BackgroundOlaparib maintenance therapy for platinum-sensitive relapsed ovarian cancer has been approved in Japan since April 2018. Here, we report...
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Socket Preservation in Dentistry: a Comprehensive Review on Efficacy, Tissue Volume Maintenance, and Economic Considerations with Focus on Membrane Types and Bone Regeneration Dynamics
Purpose of the ReviewSocket preservation post-tooth extraction is crucial for optimal conditions for subsequent dental implant placement. This review...
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Efficacy of chidamide maintenance therapy versus autologous stem cell transplantation versus observation as a post-remission choice in the survival of adult patients with peripheral T-cell lymphoma: Post hoc analysis of a prospective, multicenter, phase 2 study in China
In this prospective, multicenter, Phase 2 clinical trial (NCT02987244), patients with peripheral T-cell lymphomas (PTCLs) who had responded to...
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Efficacy and safety of isotonic versus hypotonic intravenous maintenance fluids in hospitalized children: an updated systematic review and meta-analysis of randomized controlled trials
BackgroundIatrogenic hyponatremia is a common complication following intravenous maintenance fluid therapy (IV-MFT) in hospitalized children. Despite...
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Electroconvulsive Therapy as Maintenance Treatment in Psychiatric Disorders
Purposeof ReviewFollowing symptom remission with acute electroconvulsive therapy (ECT), maintenance ECT (M-ECT) is often used to prevent relapse....
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Examining the benefit of a higher maintenance dose of extended-release buprenorphine in opioid-injecting participants treated for opioid use disorder
BackgroundBUP-XR (SUBLOCADE ® ) is the first buprenorphine extended-release subcutaneous injection approved in the USA for monthly treatment of...
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The efficacy and safety of a single maintenance laser treatment for stress urinary incontinence: a double-blinded randomized controlled trial
Introduction and hypothesisTo evaluate the efficacy and safety of a single carbon dioxide (CO 2 ) laser maintenance treatment in women previously...
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Determinants of physical activity maintenance and the acceptability of a remote coaching intervention following supervised exercise oncology rehabilitation: a qualitative study
PurposeThe purpose of the study was to investigate perceived determinants of physical activity (PA) maintenance following supervised exercise...
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The clinical efficacy of azathioprine as maintenance treatment for autoimmune pancreatitis: a systematic review and meta-analysis
The effectiveness of azathioprine (AZA) in preventing relapse and maintaining autoimmune pancreatitis (AIP) remission has been reported; however,...
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The efficacy of dupilumab in induction and maintenance of remission in an adult patient with steroid-dependent eosinophilic enteritis (EoN)
Eosinophilic enteritis (EoN) is associated with an eosinophilic infiltrate confined to the small intestine, but treatment options other than diet and...
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Modified docetaxel, cisplatin, and 5-fluorouracil combination regimen and capecitabine maintenance in metastatic gastric cancer: toxicity and efficacy results
BackgroundLittle progress has been made, and there is an unmet medical need for treatment of metastatic gastric cancer (MGC)....
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Maintenance avelumab therapy for urothelial carcinoma in a hemodialysis patient: a case report
In recent years, immune checkpoint inhibitors have attracted attention in treatment for urothelial carcinoma. However, many clinical trials included...
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A randomised, double-blind, placebo-controlled study to evaluate the safety and efficacy of lamotrigine in the maintenance treatment of Chinese adult patients with bipolar I disorder
BackgroundLamotrigine is approved as a maintenance therapy for bipolar I disorder in many countries, including China in 2021. This study evaluated...
