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The role of miRNA-29b1, MMP-2, MMP-9 mRNAs, and proteins in early diagnosis of HCC
BackgroundHepatocellular carcinoma (HCC) is a common, serious malignancy with a dismal prognosis. As HCC is frequently missed in its early stages,...
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Blood MMP-9 measured at 2 years after lung transplantation as a prognostic biomarker of chronic lung allograft dysfunction
BackgroundLong-term outcomes of lung transplantation (LTx) remain hampered by chronic lung allograft dysfunction (CLAD). Matrix metalloproteinase 9...
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TEM1 up-regulates MMP-2 and promotes ECM remodeling for facilitating invasion and migration of uterine sarcoma
ObjectivesTo explore the correlation between tumor endothelial marker 1 (TEM1) and matrix metalloproteinase 2 (MMP-2) in uterine sarcoma and their...
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The evaluation of the MMP-2/TIMP-1 ratio in peptic ulcer and its association with refractory helicobacter pylori infection
BackgroundHelicobacter pylori ( H. pylori ) is one of the leading causes of peptic ulcers, and its treatment is a worldwide challenge. Matrix...
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Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice
BackgroundIdiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease characterized by exuberant deposition of extracellular matrix...
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Probiotic-derived silver nanoparticles target mTOR/MMP-9/BCL-2/dependent AMPK activation for hepatic cancer treatment
Recent advances in nanotechnology have offered novel ways to combat cancer. By utilizing the reducing capabilities of Lactobacillus acidophilus ,...
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Amaranthus viridis methanolic extract and its active compound kaempferol ameliorate myocardial infarction induced by isoproterenol through decreasing oxidative stress and cell death via Nrf-2/HO-1 and MMP/Bax/Bcl-2/TLR-4 pathways in rats
The cardioprotective impact of Amaranthus viridis methanolic extracts (AVMEs) and its active phytoconstituent kaempferol on isoproterenol...
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Synovial fluid analysis of MMP-2, MMP-9, and COX-2 as diagnostic markers for naturally occurring septic and aseptic arthritis in horses
The aim of this study was to explore the diagnostic value of matrix metalloproteinase (MMP)-2 and -9, and cyclooxygenase-2 (COX-2) enzymes in the...
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Matrix Metalloproteinases (MMP-2) and Tissue Inhibitors of Metalloproteinases (TIMP-2) in Male Inguinal Hernia Patients at Different Ages
BackgroundCollagen metabolism, controlled by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), might be related...
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Angiopoietin-2/-1 ratios and MMP-3 levels as an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica
BackgroundDiagnosing patients with giant cell arteritis (GCA) remains difficult. Due to its non-specific symptoms, it is challenging to identify GCA...
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Expression of metalloproteinases MMP-2 and MMP-9 is associated to the presence of androgen receptor in epithelial ovarian tumors
BackgroundThe current study evaluated the metalloproteinases MMP-2 and MMP-9 expression in epithelial cells and the surrounding stroma in ovarian...
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Elevated serum matrix metalloprotease (MMP-2) as a candidate biomarker for stable COPD
BackgroundThe increasing trend of Chronic Obstructive Pulmonary Disease (COPD) in becoming the third leading cause of deaths by 2020 is of great...
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Use of nimotuzumab combined with cisplatin in treatment of nasopharyngeal carcinoma and its effect on expressions of VEGF and MMP-2
PurposeThis paper aims to observe the expressions of VEGF and MMP-2 in patients with nasopharyngeal carcinoma treated by nimotuzumab combined with...
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Matrix Metalloproteinases (MMP-2) and Tissue Inhibitors of Metalloproteinases (TIMP-2) in Patients with Inguinal Hernias
BackgroundThe development of inguinal hernia might be related with collagen metabolism, which was regulated by matrix metalloproteinases (MMPs) and...
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PTGER3 and MMP-2 play potential roles in diabetic nephropathy via competing endogenous RNA mechanisms
BackgroundDiabetic nephropathy (DN) is a primary complication of diabetes mellitus (DM). The pathology of DN is still vague, and diagnostic accuracy...
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Association between the polymorphisms in MMP-2 and MMP-9 with adiposity and mammographic features
BackgroundMatrix metalloproteinases (MMP)-2 and -9 may play an important role in adipogenesis and carcinogenesis. We investigated whether some...
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Up-regulation of MMP-2 by histone H3K9 β-hydroxybutyrylation to antagonize glomerulosclerosis in diabetic rat
AimsBesides energy supply, β -hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its...
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MMP-2 salivary activity in type 2 diabetes mellitus patients
BackgroundType 2 diabetes mellitus (T2DM) and periodontitis are chronic inflammatory diseases with a bidirectional relationship. The uncontrolled...
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Predictive potential of various plasma inflammation-, angiogenesis-, and extracellular matrix remodeling-associated mediators for intra-amniotic inflammation and/or microbial invasion of the amniotic cavity in preterm labor
PurposeTo determine whether various inflammatory-, angiogenic/anti-angiogenic-, and extracellular matrix remodeling-associated proteins in plasma,...
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Hydrogen Sulfide Ameliorates Heart Aging by Downregulating Matrix Metalloproteinase-9
PurposeAging contributes significantly to cardiovascular diseases and cardiac dysfunction, leading to the upregulation of matrix metalloproteinase-9...
