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The link between spirituality and longevity
We are facing an inverted demographic pyramid with continuously growing aged populations around the world. However, the advances that prolong...
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Transcriptional Regulation in the Control of Aging and Longevity
AbstractTranscription regulation is required for correct differential gene expression, which determines the development and function of all cells in...
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“Real-world” analysis of battery longevity of implantable cardioverter-defibrillators: an in-depth analysis of a prospective defibrillator database
BackgroundThere is a lack of evidence regarding contemporary implantable cardioverter-defibrillator (ICD) battery longevity. Our aim was to assess...
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The ageing thyroid: implications for longevity and patient care
Thyroid hormones have vital roles in development, growth and energy metabolism. Within the past two decades, disturbances in thyroid hormone action...
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In Vitro Maturation, In Vitro Oogenesis, and Ovarian Longevity
This paper will review a remarkable new approach to in vitro maturation “IVM” of oocytes from ovarian tissue, based on our results with in vitro...
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Declining life expectancy in the Great Lakes region: contributors to Black and white longevity change across educational attainment
BackgroundThe East North Central Census division (aka the Great Lakes region) experienced a decrease in life expectancy of 0.3 years from 2014 to...
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GWAS of biological aging to find longevity genes in schizophrenia
Schizophrenia (SCZ) is a severe psychotic disorder associated with premature mortality and aging. Moreover, the symptoms and progression of...
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Who live longer than their age peers: individual predictors of longevity among older individuals
BackgroundThere are a very few studies focusing on the individual-based survival with a long follow-up time.
AimTo identify predictors and determine...
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MicroRNAs influence and longevity
BackgroundMiRNAs play critical roles in the regulation of cellular function, life span, and the aging process. They can affect longevity positively...
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Comparison of long-term effects of metformin on longevity between people with type 2 diabetes and matched non-diabetic controls
BackgroundMetformin, a medication for type 2 diabetes, has been linked to many non-diabetes health benefits including increasing healthy lifespan....
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Towards Allograft Longevity: Leveraging Omics Technologies to Improve Heart Transplant Outcomes
Purpose of ReviewHeart transplantation (HT) remains the optimal therapy for patients living with end-stage heart disease. Despite recent improvements...
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Four novel genes associated with longevity found in Cane corso purebred dogs
BackgroundLongevity-related genes have been found in several animal species as well as in humans. The goal of this study was to perform genetic...
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Changes in longevity inequality by education among OECD countries before the COVID-19 pandemic
BackgroundDisparities in life expectancy between socioeconomic groups are one of the main challenges for health policy, and their reduction over time...
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TOMM40 genetic variants associated with healthy aging and longevity: a systematic review
IntroductionHealthy aging relies on mitochondrial functioning because this organelle provides energy and diminishes oxidative stress. Single...
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The anti-aging role of metformin, clinical applications to pursue the longevity road
BackgroundMetformin, an oral antidiabetic drug widely used for over 60 years, has been recognized for its safety and effectiveness in the treatment...
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Impact of fertility on the longevity of older rural Chinese women: an analysis of a longitudinal survey
BackgroundThis study evaluates the impact of fertility during the childbearing period on the longevity of older rural Chinese women and verifies...
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Genetic, Social, and Lifestyle Drivers of Healthy Aging and Longevity
Purpose of Review“Healthy aging” is the state of the aging process in which a person can maintain physical, social, mental, and spiritual wellness....
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Healthy lifestyle and longevity genetics associated with healthy life expectancy and years of life gained at age of 60 years: A prospective cohort study
AimTo investigate the relationships between healthy lifestyles, longevity genetics, and major chronic noncommunicable diseases (NCDs) and death, and...
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The 90 plus: longevity and COVID-19 survival
The world population is getting older and studies aiming to enhance our comprehension of the underlying mechanisms responsible for health span are of...
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Exploring the effects of the dietary fiber compound mediated by a longevity dietary pattern on antioxidation, characteristic bacterial genera, and metabolites based on fecal metabolomics
BackgroundAge-related dysbiosis of the microbiota has been linked to various negative health outcomes. This study aims to investigate the effects of...
