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1. Aberrant expression of LINC00346 regulates cell migration and proliferation via competitively binding to miRNA-148a-3p/Dnmt1 in Hirschsprung’s disease

   Background

   Hirschsprung’s disease (HSCR) is a common birth defect caused by dysplasia of neural crest cells in the gut. Long noncoding RNAs (lncRNAs)...

   Long Li, **ao Li, ... Rongde Wu in Pediatric Surgery International

   Article 14 July 2022
   

2. LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription

   Although multiple factors are known to contribute to pancreatic ductal adenocarcinoma (PDAC) progression, the role of long non-coding RNAs (lncRNAs)...

   Wan-**n Peng, Rong-Zhang He, ... Yin-Yuan Mo in Oncogene

   Article 07 August 2019
   

3. Abnormal pattern of vitamin D receptor-associated genes and lncRNAs in patients with bipolar disorder

   Background

   Bipolar disorder (BD) is a multifactorial condition. Several signaling pathways affect development of this disorder. With the purpose of...

   Reyhane Eghtedarian, Soudeh Ghafouri-Fard, ... Mohammad Taheri in BMC Psychiatry

   Article Open access 12 March 2022
   

4. Evaluation of expression of VDR-associated lncRNAs in COVID-19 patients

   Background

   Coronavirus disease 2019 (COVID-19) has been shown to cause serious health problems among them is the Acute Respiratory Distress syndrome...

   Mohammad Taheri, Lina Moallemi Rad, ... Soudeh Ghafouri-Fard in BMC Infectious Diseases

   Article Open access 19 June 2021
   

5. Aseptic loosening around total joint replacement in humans is regulated by miR-1246 and miR-6089 via the Wnt signalling pathway

   Background

   Total joint replacement for osteoarthritis is one of the most successful surgical procedures in modern medicine. However, aseptic loosening...

   Yi Deng, Kate Phillips, ... Rachel W. Li in Journal of Orthopaedic Surgery and Research

   Article Open access 29 January 2024
   

6. Non-coding RNAs in breast cancer: with a focus on glucose metabolism reprogramming

   Breast cancer is the tumor with the highest incidence in women worldwide. According to research, the poor prognosis of breast cancer is closely...

   Junjie Liang, Chun Ye, ... Ke Wei in Discover Oncology

   Article Open access 19 May 2023
   

7. Potentials of long non-coding RNAs as biomarkers of colorectal cancer

   Colorectal cancer (CRC) is the third most common malignant tumor worldwide and the fourth major cause of cancer-related death, with high morbidity...

   Yan Lv, Yanhua Wang, ... Huahua Su in Clinical and Translational Oncology

   Article 17 May 2022
   

8. NF-κB-activated SPRY4-IT1 promotes cancer cell metastasis by downregulating TCEB1 mRNA via Staufen1-mediated mRNA decay

   Previous study demonstrated that most long non-coding RNAs (lncRNAs) function as competing endogenous RNAs or molecular sponges to negatively...

   Lin Zhao, Longyang Jiang, ... Minjie Wei in Oncogene

   Article Open access 23 June 2021
   

9. Current status of molecular diagnostic approaches using liquid biopsy

   Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers, and develo** an efficient and reliable approach for its...

   Kenji Takahashi, Yohei Takeda, ... Yusuke Mizukami in Journal of Gastroenterology

   Article Open access 20 July 2023
   

10. The regulation of protein translation and its implications for cancer

    In addition to the deregulation of gene transcriptions and post-translational protein modifications, the aberrant translation from mRNAs to proteins...

    ** Song, Fan Yang, ... **an Wang in Signal Transduction and Targeted Therapy

    Article Open access 18 February 2021
    

11. ZNF655 accelerates progression of pancreatic cancer by promoting the binding of E2F1 and CDK1

    Pancreatic cancer has an extremely terrible prognosis and is a common cause of cancer death. In this study, the clinic value, biological function and...

    Zhuo Shao, Chenggang Li, ... Hua Fan in Oncogenesis

    Article Open access 04 August 2022
    

12. Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

    Background

    Sevoflurane is considered as a lung-protective factor in acute lung injury (ALI), but the underlying molecular mechanism remains largely...

    Zhiling Fu, **uying Wu, ... Yan Zhang in BMC Pulmonary Medicine

    Article Open access 26 April 2022
    

13. Clinical implications and molecular mechanisms of Cyclin-dependent kinases 4 for patients with hepatocellular carcinoma

    Background

    Hepatocellular carcinoma (HCC) was frequently considered as a kind of malignant tumor with a poor prognosis. Cyclin-dependent kinases...

    Zhong-liu Wei, **n Zhou, ... Tao Peng in BMC Gastroenterology

    Article Open access 22 February 2022
    

14. MYC in liver cancer: mechanisms and targeted therapy opportunities

    MYC, a major oncogenic transcription factor, regulates target genes involved in various pathways such as cell proliferation, metabolism and immune...

    Furong Liu, Zhibin Liao, Zhanguo Zhang in Oncogene

    Article 13 October 2023
    

15. The JAK/STAT signaling pathway: from bench to clinic

    The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway was discovered more than a quarter-century ago. As a...

    **aoyi Hu, **g li, ... Wei Wang in Signal Transduction and Targeted Therapy

    Article Open access 26 November 2021
    

16. Methylseleninic Acid Suppresses Breast Cancer Growth via the JAK2/STAT3 Pathway

    Previous studies show that methylseleninic acid (MSA), which is the most common selenium derivative used as a drug in humans, exerts specific...

    Changwei Qiu, Tao Zhang, ... Ganzhen Deng in Reproductive Sciences

    Article 01 June 2019

17. Insights from Global Analyses of Long Noncoding RNAs in Breast Cancer

    Purpose of Review

    The goal of this review was to compare and contrast the results and implications from several recent transcriptomic studies that...

    Andrew J. Warburton, David N. Boone in Current Pathobiology Reports

    Article 23 January 2017