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Neoadjuvant Chemotherapy Improves Feasibility of Larynx Preservation and Prognosis in Resectable Locally Advanced Cervical Esophageal Cancer
BackgroundThe optimal strategy for cervical advanced esophageal cancer remains controversial in terms of oncologic outcome as well as vocal and...
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Non-squamous Cancers of the Larynx
Purpose of ReviewAlthough non-squamous tumors of the larynx are really rare, they may not always be viewed from the same perspective in the...
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CT and MR anatomy of the larynx and hypopharynx
Imaging of the larynx and hypopharynx is frequently requested to assess the extent of neoplasms beyond the field of view of endoscopic evaluation....
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Primitive Neuroectodermal Tumour of the Larynx: A Rare Case Report
Ewing’s sarcoma/primitive neuroectodermal tumour is a malignant small round blue cell tumour of neuroectodermal origin that affects bones and soft...
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PD-1 Inhibitors combined with paclitaxel (Albumin-bound) and cisplatin for larynx preservation in locally advanced laryngeal and hypopharyngeal squamous cell carcinoma: a retrospective study
Backgroundlaryngeal and hypopharyngeal squamous cell carcinoma (SCC) is a common head and neck cancer with significant impact on quality of life due...
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Validation of a prognostic model for predicting larynx preservation outcome (TALK score) in a Southern European population
ObjectiveLarynx preservation is the current standard for locally advanced (LA) laryngeal/hypopharyngeal tumors, but not all patients respond as...
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Survival Outcomes of Non-squamous Cell Carcinoma and Rare Squamous Cell Carcinoma Variants of the Larynx
The literature focuses primarily on laryngeal differentiated squamous cell carcinoma (SCC), and only a limited number of studies have evaluated the...
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Rekonstruktionsmöglichkeiten des Larynx
Laryngeal cancer and its treatment lead to disturbances of breathing, voice, and protection from aspiration. The nature and extent of posttherapeutic...
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Global trend and risk factors of the disease burden for pharynx and larynx cancers between 1990 and 2019: a systematic analysis of the global burden of disease study 2019
BackgroundPharynx and larynx cancers (PLCs) are the top killer cancers in head and neck and significantly affect the quality of life of patients. A...
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VoiceS: voice quality after transoral CO2 laser surgery versus single vocal cord irradiation for unilateral stage 0 and I glottic larynx cancer—a randomized phase III trial
BackgroundSurgery and radiotherapy are well-established standards of care for unilateral stage 0 and I early-stage glottic cancer (ESGC). Based on...
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Textbook of Surgery of Larynx and Trachea
This fully revised and expanded second edition provides a comprehensive, up-to-date overview of the fundamentals of contemporary larynx and trachea...
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Survival and Quality of Life (QoL) Enhancing Effect of Surgery in Larynx and Hypopharynx Cancers
The critical role of surgery in the overall management of larynx and hypopharynx cancers continues to be undermined in all major outcome studies...
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Value and role of surgical margins in transoral laser microsurgery of the larynx, literature review and clinical considerations
PurposeThere is no agreement on the most appropriate post-operative pathway for the management of positive margins after laser cordectomy for early...
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Dual anticancer activity of Aspergillus nidulans pigment and Ionizing γ-Radiation on human larynx carcinoma cell line
BackgroundFungi are a readily available source of naturally generated colored compounds. These compounds might be used as radiosensitizers for...
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125 years of head and neck radiotherapy: could organ-sparing radiotherapy of larynx cancer have prevented World War I?
PurposeWe aim to recapitulate the rapid development of head and neck radiotherapy in the context of otorhinolaryngology (ORL) medicine starting...
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Fungal laryngitis: a forgotten disease mimicking laryngeal cancer—a case report
BackgroundFungal laryngitis is a fungal infection of the larynx which is an extremely rare clinical entity, especially in immunocompetent patients....
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Primary mucosal melanoma of the larynx: systematic review of the literature and qualitative synthesis
PurposePrimary mucosal melanoma of the larynx (PLM) is a rare entity among head and neck cancers. Due to its rarity, clear protocols of management...
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Comparison of Survival Outcomes Between Larynx-Preserving Open Partial Pharyngectomy and Radiotherapy or Chemoradiotherapy in Patients with Hypopharyngeal Squamous Cell Carcinoma: A Single-Center Retrospective Analysis with Inverse Probability of Treatment Weighting Adjustments
BackgroundThere is a group of hypopharyngeal squamous cell carcinoma (HPSCC) patients for whom larynx-preserving open partial pharyngectomy (PP) and...
