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Hotspots and trends of microglia in Alzheimer's disease: a bibliometric analysis during 2000–2022
BackgroundAlzheimer's disease is one common type of dementia. Numerous studies have suggested a correlation between Alzheimer's disease and...
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Phosphodiesterase-5 inhibitors use and the risk of alzheimer's disease: a systematic review and meta-analysis
BackgroundThe management of Alzheimer's disease (AD) poses considerable challenges, necessitating the pursuit of innovative therapeutic approaches....
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Contribution of Iranian researchers in Alzheimer's disease research: A 10 years scientometric analysis
BackgroundAlzheimer's disease is the most common form of dementia and is a rising issue for global health. Iran is struggling with a growing number...
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Diagnostic performance of MRI radiomics for classification of Alzheimer's disease, mild cognitive impairment, and normal subjects: a systematic review and meta-analysis
BackgroundAlzheimer's disease (AD) is a debilitating neurodegenerative disease. Early diagnosis of AD and its precursor, mild cognitive impairment...
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Targeting the molecular web of Alzheimer’s disease: unveiling pathways for effective pharmacotherapy
IntroductionAlzheimer’s disease is a neurocognitive disorder that affects elderly people by slowly impaired cognition, dementia, and gets worse with...
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Two decades of research on the role of diet in Alzheimer’s disease (2003–2023): a bibliometric and visual analysis based on CiteSpace
BackgroundIn recent years, the impact of diet on Alzheimer's disease (AD) as a modifiable lifestyle has attracted widespread attention. We aimed to...
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Alzheimer’s disease and drug delivery across the blood–brain barrier: approaches and challenges
Alzheimer's disease (AD) is a diverse disease with a complex pathophysiology. The presence of extracellular β-amyloid deposition as neuritic plaques...
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Potential role of recombinant growth differentiation factor 11 in Alzheimer’s disease treatment
Alzheimer's disease (AD) is a neurodegenerative disease closely related to the accumulation of beta-amyloid (Aβ) plaques. Growth differentiation...
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A comparative study of bibliometric analysis on old adults’ cognitive impairment based on Web of Science and CNKI via CiteSpace
IntroductionThe purpose of this study was to analyze the current status, the research hot spots and frontiers of cognitive impairment (CI) on old...
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PSEN2 and ABCA7 variants causing early-onset preclinical pathological changes in Alzheimer's disease: a case report and literature review
BackgroundAlzheimer’s disease (AD) is a debilitating and highly heritable neurodegenerative disease. Early-onset AD (EOAD) was defined as AD...
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Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations
BackgroundSolanum lycopersicum Linn. (Tomato, Family Solanaceae) is one of the fruits that are most consumed worldwide. The current research intends...
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Low vitamin D serum levels as risk factor of Alzheimer’s disease: a systematic review and meta-analysis
Past literatures have reported that changes in serum vitamin D levels are related to cognitive dysfunctions, such as dementia, including Alzheimer’s...
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Association between Mediterranean diet and dementia and Alzheimer disease: a systematic review with meta-analysis
BackgroundDementia affects 5–8% of the population aged over 65 years (~50 million worldwide). Several factors are associated with increased risk,...
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Therapeutic Mechanism of Kai **n San on Alzheimer’s Disease Based on Network Pharmacology and Experimental Validation
ObjectiveTo explore the specific pharmacological molecular mechanisms of Kai **n San (KXS) on treating Alzheimer’s disease (AD) based on network...
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Markers for the detection of Lewy body disease versus Alzheimer’s disease in mild cognitive impairment: a systematic review and meta-analysis
BackgroundMild cognitive impairment (MCI) may evolve into dementia. Early recognition of possible evolution to Alzheimer's disease (AD) and dementia...
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Evaluation of the effects of curcumin on chronic obstructive pulmonary disease with a bio-computational approach
BackgroundAccording to the increasing trend of COPD, the timely diagnosis and treatment of the disease can reduce the high costs to the health...
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A Systematic Review of Clinical Practice Guidelines for Alzheimer’s Disease and Strategies for Future Advancements
IntroductionAlzheimer’s disease (AD) is a disease continuum from pathophysiologic, biomarker and clinical perspectives. With the advent of advanced...
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Mechanisms of Acupuncture in Improving Alzheimer’s Disease Caused by Mitochondrial Damage
Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases among the elderly and it accounts for nearly 80% of all dementias. The...
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Akt signaling pathway: a potential therapy for Alzheimer’s disease through glycogen synthase kinase 3 beta inhibition
Alzheimer’s disease (AD) is a form of dementia marked by the accumulation of neuritic plaques and neurofibrillary tangles through the action of...
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The FDA-approved anti-amyloid-β monoclonal antibodies for the treatment of Alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials
BackgroundAlzheimer’s disease (AD) is a worldwide public health problem and is difficult to cure. Drugs aimed at slowing the progression of the...
