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  1. JAK Inhibitor Use for the Inpatient Dermatologist

    Purpose of Review

    JAK inhibitors (JAKis) are a novel class of therapeutics that have shown great promise in dermatology. This review provides an...

    Eric **a, Ahana Gaurav, ... Arash Mostaghimi in Current Dermatology Reports
    Article 18 November 2023

  2. JAK in the [Black] Box: A Dermatology Perspective on Systemic JAK Inhibitor Safety

    Janus kinase (JAK) inhibitors are immunomodulatory agents with broad potential for use within dermatology. However, the US Food and Drug...

    Sarina B. Elmariah, Jeffrey S. Smith, Joseph F. Merola in American Journal of Clinical Dermatology
    Article 09 June 2022

  4. Effect and mechanism of HMG-CoA reductase inhibitor on the improvement of elderly essential hypertension-induced vascular endothelial function impairment based on the JAK/STAT pathway

    Objective

    Our research was designed to figure out the influence and mechanism of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor...

    Wen Yuan, Hongjun Fan, ... Yong Yan in Diagnostic Pathology
    Article Open access 28 September 2023

  5. Oral surveillance and JAK inhibitor safety: the theory of relativity

    The published results of the post-marketing ORAL Surveillance study, which compared the Janus kinase (JAK) inhibitor tofacitinib with anti-TNF...

    Kevin L. Winthrop, Stanley B. Cohen in Nature Reviews Rheumatology
    Article 22 March 2022

  6. Upfront allogeneic transplantation versus JAK inhibitor therapy for patients with myelofibrosis: a North American collaborative study

    Allogeneic hematopoietic cell transplantation (HCT) is the only curative therapy for myelofibrosis (MF) and is recommended for patients with higher...

    Dawn Maze, Murat O. Arcasoy, ... Vikas Gupta in Bone Marrow Transplantation
    Article Open access 08 November 2023

  7. JAK-Inhibitor-Creme als Gamechanger für die Vitiligo

    Redaktion Facharztmagazine in hautnah dermatologie
    Article 22 March 2024

  8. JAK-Inhibitor vergleichbar wirksam wie orales Prednisolon

    Anne Benckendorff in Gastro-News
    Article 16 February 2024

  12. Efficacy and safety of JAK inhibitors in rheumatoid arthritis: update for the practising clinician

    Janus kinase (JAK) inhibitors, including tofacitinib, baricitinib, upadacitinib and filgotinib, are increasingly used in the treatment of rheumatoid...

    Zoltán Szekanecz, Maya H. Buch, ... Roy Fleischmann in Nature Reviews Rheumatology
    Article 12 January 2024

  14. EU-Zulassung für oralen JAK-Inhibitor

    Redaktion Facharztmagazine in ästhetische dermatologie & kosmetologie
    Article 18 October 2022

  15. Scope of JAK Inhibitors in Children: Recent Evidence and Way Forward

    Over the last decade, there has been an increase in the use of targeted therapy using small molecules such as Janus kinase (JAK) inhibitors. Since...

    Narendra Kumar Bagri, Christine Chew, A. V. Ramanan in Pediatric Drugs
    Article 29 September 2023

  16. Treatment of in vitro generated Langerhans cells with JAK-STAT inhibitor reduces their inflammatory potential

    Alopecia areata (AA) is a condition in which hair is lost in small regions or over the entire body. It has a prevalence of 1 in 1000 and has a great...

    Sterkens Ann, Janssens Ibo, ... Cools Nathalie in Clinical and Experimental Medicine
    Article 25 October 2022

  18. Retrospective comparative study of the efficacy of JAK inhibitor (tofacitinib) in the treatment of systemic sclerosis-associated interstitial lung disease

    The oral Janus kinases inhibitor (JAKi) has improved the management of skin manifestations in systemic sclerosis (SSc), and our study aimed to...

    Zhou Junfei, Gao Meihua, ... Shi Lipu in Clinical Rheumatology
    Article 19 June 2023

  19. JAK-Inhibitor mit Potenzial

    Redaktion Facharztmagazine in Gastro-News
    Article 25 August 2022
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