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Current status of support for Automated External Defibrillators (AEDs) in public places and factors influencing their use in China: a cross-sectional study
AimTo investigate the support of residents in China for the provision of AEDs in public places and the factors affecting support.
Subject and methods ...
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Antiepileptic Strategies for Patients with Primary and Metastatic Brain Tumors
Seizure activity is common in patients with primary and metastatic brain tumors, affecting more than 50% of cases over the course of their disease....
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Assessment of asymmetric dimethylarginine and homocysteine in epileptic children receiving antiepileptic drugs
BackgroundEpilepsy is a neurological disease that requires long-term antiepileptic drugs (AEDs). The old generation of AEDs may affect serum...
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Cannabidiol Interactions with Medications, Illicit Substances, and Alcohol: a Comprehensive Review
Cannabidiol, a non-intoxicating phytocannabinoid, has potential therapeutic effects over a broad range of disorders. Recently, there has been...
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Carbamazepine regulates USP10 through miR-20a-5p to affect the deubiquitination of SKP2 and inhibit osteogenic differentiation
BackgroundAntiepileptic drugs (AEDs) harm bone health and are significantly associated with osteoporosis development. In this study, we aimed to...
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Effect of long-term administration of clonazepam, carbamazepine, and valproate on cognitive, psychological, and personality changes in adult epilepsy: a case–control study
BackgroundEpilepsy can be treated with antiepileptic drugs (AEDs) which may have psychiatric and behavioral side effects. Additionally, the...
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Calculation and management of ketogenic diet parenteral nutrition in super-refractory status epilepticus
Super-refractory status epilepticus (SRSE) is an important neurological emergency associated with high mortality and morbidity and poses a heavy...
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Perifocal edema is a risk factor for preoperative seizures in patients with meningioma WHO grade 2 and 3
BackgroundPatients with intracranial meningiomas frequently suffer from tumor-related seizures prior to resection, impacting patients’ quality of...
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Sturge–Weber syndrome: an update for the pediatrician
BackgroundSturge–Weber syndrome (SWS) is a rare congenital neurocutaneous disorder characterized by the simultaneous presence of both cutaneous and...
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Efficacy of intravenous levetiracetam versus phenytoin in convulsive status epilepticus and acute repetitive seizures in children
PurposePhenytoin is one of the most used antiepileptic drugs (AEDs), but it has serious potential side effects and drug interactions. Although...
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Narrative Review of Topiramate: Clinical Uses and Pharmacological Considerations
Due to the diverse mechanisms of action of antiseizure drugs, there has been a rise in prescriptions of these drugs for non-epileptic pathologies....
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Management of antiepileptic drug–induced nutrition-related adverse effects
Although antiepileptic drugs (AEDs) are mainstay of the treatment of epilepsy, they are associated with significant adverse effects. The present...
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A review on epilepsy, current treatments, and potential of medicinal plants as an alternative treatment
Epilepsy is considered common neurological diseases that threaten the lives of millions of people all around the world. Since ancient times,...
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Psychotropic drug-induced hyponatremia: results from a drug surveillance program–an update
Hyponatremia (HN) is the most common electrolyte imbalance (defined as a serum sodium concentration Na(S) of < 130 mmol/l) and often induced by...
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Effects of Gabapentin and Pregabalin on Calcium Homeostasis: Implications for Physical Rehabilitation of Musculoskeletal Tissues
Purpose of ReviewIn this review, we discuss the mechanism of action of gabapentinoids and the potential consequences of long-term treatment with...
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SEOM-GEINO clinical guidelines for high-grade gliomas of adulthood (2022)
High-grade gliomas (HGG) are the most common primary brain malignancies and account for more than half of all malignant primary brain tumors. The new...
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Chronic pediatric diseases and risk for reading difficulties: a narrative review with recommendations
AbstractLiteracy is a major social determinant of health, rooted in skills that develop during early childhood. Children arriving at kindergarten...
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Case report of antiseizure medicine-induced long QT syndrome and a literature review
BackgroundTo realize the clinical characteristics of long QT syndrome (LQTS) caused by antiseizure medicines (ASMs), and to improve the prevention...
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Genetic analysis of developmental and epileptic encephalopathy caused by novel biallelic SZT2 gene mutations in three Chinese Han infants: a case series and literature review
BackgroundDevelopmental and epileptic encephalopathy (DEE) exhibits phenotypic and genetic heterogeneity. Biallelic variants of the SZT2 gene can...
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Neurophysiological assessment of cortical activity in DEPDC5- and NPRL3-related epileptic mTORopathies
BackgroundMutations in the GATOR1 complex genes, DEPDC5 and NPRL3, play a major role in the development of lesional and non-lesional focal epilepsy...
