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Clinical and immunological characterisation of patients with common variable immunodeficiency related immune thrombocytopenia
Primary Immune thrombocytopenia (ITP) is an autoimmune disease. Secondary ITP occurs in patients with underlying diseases such as common variable...
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Factors associated with immunological non-response after ART initiation: a retrospective observational cohort study
BackgroundAmong people living with HIV (PLHIV) on antiretroviral therapy (ART), the mortality of immunological non-responders (INRs) is higher than...
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Olfactory impairment in patients with primary Sjogren’s syndrome and its correlation with organ involvement and immunological abnormalities
ObjectivePatients with autoimmune diseases often present with olfactory impairment. The aim of the study was to assess the olfactory functions of...
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The anti-inflammatory and immunological properties of SGLT-2 inhibitors
BackgroundSodium-glucose cotransporter-2 inhibitors (SGLT-2i) are antidiabetic oral drugs that act on proximal renal tubules promoting renal glucose...
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STAT expression and TFH1 cells in CVID granulomatosis and sarcoidosis: immunological and histopathological comparisons
Granulomatous disease is a serious complication of common variable immunodeficiency (CVID-GD) that occurs in 8–22% of these patients and can mimic...
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Clinical characteristics and immunological abnormalities of Castleman disease complicated with autoimmune diseases
PurposeTo explore the clinical features and immunological mechanisms of Castleman disease (CD) complicated with autoimmune diseases (AID).
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Prior tuberculosis, radiographic lung abnormalities and prevalent diabetes in rural South Africa
BackgroundGrowing evidence suggests that chronic inflammation caused by tuberculosis (TB) may increase the incidence of diabetes. However, the...
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Stepwise diagnostic algorithm for high-attenuation pulmonary abnormalities on CT
High-attenuation pulmonary abnormalities are commonly seen on CT. These findings are increasingly encountered with the growing number of CT...
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Persistent immune abnormalities discriminate post-COVID syndrome from convalescence
BackgroundInnate lymphoid cells (ILCs) are key organizers of tissue immune responses and regulate tissue development, repair, and pathology....
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Lipid abnormalities in pediatric kidney transplant recipients on steroid withdrawal maintenance immunosuppression
BackgroundDyslipidemia is a modifiable risk factor for cardiovascular disease. The prevalence of dyslipidemia in pKTR (pediatric kidney transplant...
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Atrial depolarization abnormalities in pulmonary sarcoidosis
BackgroundCardiac sarcoidosis, often manifested as sudden death, can be the first manifestation of sarcoidosis. Since 12-lead electrocardiogram (ECG)...
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Anti-sperm Antibodies as an Increasing Threat to Male Fertility: Immunological Insights, Diagnostic and Therapeutic Strategies
It is a fact that sperm possess antigenic properties. Substantial scientific research suggests that specific antibodies that attach to sperm antigens...
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Correlation between neuropsychiatric systemic lupus erythematosus and immunological markers: a real-world retrospective study
ObjectivesThis study aimed to investigate disparities in clinical profiles and autoantibody patterns between patients with and without...
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Topographical Distribution of Neuroanatomical Abnormalities Following COVID-19 Invasion
PurposeThis systematic review is aimed at synthesising the literature base to date on the frequency and topographical distribution of neuroanatomical...
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Immunological risk and complement genetic evaluations in early onset de novo thrombotic microangiopathy after living donor kidney transplantation: A Japanese multicenter registry
BackgroundThrombotic microangiopathy (TMA) after kidney transplantation (KTx), particularly early onset de novo (dn) TMA, requires immediate...
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Clinical features and prognosis of pediatric acute lymphocytic leukemia with JAK-STAT pathway genetic abnormalities: a case series
The objective of this study is to explore the clinical features and outcomes of pediatric patients with acute lymphoblastic leukemia (ALL) harboring...
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Two patients with ZAP-70 deficiency in China present with a different genetic, immunological, and clinical phenotype
Zeta(ζ)-Chain Associated Protein Kinase 70 kDa (ZAP-70) deficiency is a rare autosomal recessive primary immunodeficiency disease. Little is known...
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Association of immunological parameters with aortic dilatation in giant cell arteritis: a cross-sectional study
Aortic dilatation (AD) occurs in up to 30% of patients with giant cell arteritis (GCA). Reliable biomarkers for AD development, however, are still...
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Identification of novel homozygous asthenoteratospermia-causing ARMC2 mutations associated with multiple morphological abnormalities of the sperm flagella
PurposeTo identify the genetic causes of multiple morphological abnormalities in sperm flagella (MMAF) and male infertility in patients from two...
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Evidence underscoring immunological and clinical pathological changes associated with Sarcoptes scabiei infection: synthesis and meta-analysis
BackgroundSarcoptes scabiei is one of the most impactful mammalian parasites. There has been much research on immunological and clinical...
