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A glance on Immunogenetics Laboratory: from the origins to the future
Histocompatibility and Immunogenetics (H&I) laboratories have currently a significant relevance in clinical and research medical fields. The purpose...
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Genetic research in Immunogenetics Group of Endocrinology and Metabolism Research Institute
Due to the high prevalence of metabolic diseases and the role of genetic factors in their susceptibility, the use of basic research in this field can...
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Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder
The link between bipolar disorder (BP) and immune dysfunction remains controversial. While epidemiological studies have long suggested an...
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Immunogenetics of Kawasaki disease
Kawasaki disease (KD) is a medium vessel vasculitis that affects young children. Despite extensive research over the last 50 years, the etiology of...
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Immunogenetics of Atherosclerosis—Link between Lipids, Immunity, and Genes
Purpose of ReviewAtherosclerosis is a complex disease process with lipid as a traditional modifiable risk factor and therapeutic target in treating...
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Towards a gamete matching platform: using immunogenetics and artificial intelligence to predict recurrent miscarriage
The degree of Allele sharing of the Human Leukocyte Antigen (HLA) genes has been linked with recurrent miscarriage (RM). However, no clear genetic...
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Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors
Background Checkpoint inhibitors bring marked benefits but only in a minority of patients and may also be associated with severe adverse events....
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Correction to: Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors
Corrections are needed to the original version of this article.
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Drug rash with eosinophilia and systemic symptoms syndrome masquerading as a lymphoproliferative disorder in a young adult on immunosuppressive therapy for rheumatoid arthritis: a case report
BackgroundThis case reveals a novel presentation of drug rash with eosinophilia and systemic symptoms syndrome that mimics a lymphoproliferative...
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Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL
The somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy variable (IGHV) gene is a critical biomarker for assessing the...
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Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing
Twenty years after landmark publications, there is a consensus that the somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy...
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Fingolimod as a first- or second-line treatment in a mini-series of young Hellenic patients with adolescent-onset multiple sclerosis: focus on immunological data
BackgroundPediatric onset multiple sclerosis(POMS) is characterized by a highly active profile, often warranting treatment with high efficacy...
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Immunogenetics of glioblastoma: the future of personalized patient management
The prognosis of glioblastoma has changed little over the past two decades, with only minor improvements in length of overall survival through the...
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Association of recipient and donor interleukin 6 polymorphisms 174 and 597 with outcome after allogeneic hematopoietic stem cell transplantation in children
PurposeThe success of allogeneic hematopoietic stem cell transplantation (HSCT) is compromised by complications such as infection, relapse, and...
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Killer cell immunoglobulin receptor diversity and its relevance in the human host’s response to HIV infection in African populations
Host response to the human immune deficiency virus (HIV) involves both the innate and adaptive immune systems. As part of the innate immune system,...
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Potential Implication of HLA-DQ Heterodimer High-Resolution Ty** on Kidney Transplant Outcomes and Equity
Purpose of ReviewTo evaluate the potential implications of HLA-DQαβ heterodimer high-resolution ty** on clinical decision-making in solid organ...
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Two Decades of Publications in Journals Dedicated to Autoimmunity: A Bibliometric Analysis of the Autoimmunity Field from 2004 to 2023
To carry out an in-depth analysis of the scientific research on autoimmunity, we performed the first bibliometric analysis focusing on publications...
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Life-threatening toxicities upon Pembrolizumab intake: could pharmacokinetics be the bad guy?
PurposeWe report the case of an adult patient diagnosed with Hodgkin’s lymphoma who was scheduled for Pembrolizumab after failure of standard...