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Clinical characteristics, treatment outcomes, and prognosis in patients with MKIs-associated hand-foot skin reaction: a retrospective study
BackgroundMultikinase inhibitors (MKIs) treatment has been proven as a powerful strategy in cancer therapy. However, it is greatly hampered by its...
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Association of VEGFA and CCL4L2 polymorphisms with hand-foot skin reaction and survival of regorafenib in Japanese patients with colorectal cancer
PurposeTreatment with regorafenib, which inhibits vascular endothelial growth factor (VEGF) receptor, frequently results in hand-foot skin reaction...
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Prophylactic strategies for hand-foot syndrome/skin reaction associated with systemic cancer treatment: a meta-analysis of randomized controlled trials
PurposeHand-foot syndrome (HFS) and hand-foot skin reaction (HFSR) are common toxicities of several systemic cancer treatments. Multikinase...
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Chronic hand eczema: clinical characterization, aetiology, concomitant foot eczema and polysensitization
BackgroundChronic hand eczema (CHE) is a disabling dermatosis that presents with concomitant conditions, such as foot eczema and contact sensitization
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Prevalence of hand-foot syndrome following chemotherapy for colorectal cancer: a systematic review and meta-analysis
ObjectiveTo systematically evaluate the prevalence of hand-foot syndrome (HFS) in patients with colorectal cancer undergoing chemotherapy.
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Hand-foot syndrome in cancer patients on capecitabine: examining prevalence, impacts, and associated risk factors at a cancer centre in Malaysia
IntroductionHand-foot syndrome (HFS) significantly impacts quality of life in cancer patients undergoing capecitabine treatment. This study assessed...
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Efficacy of regional cooling + oral dexamethasone for primary prevention of hand-foot syndrome associated with pegylated liposomal doxorubicin
PurposePegylated liposomal doxorubicin (PLD)-induced hand-foot syndrome (HFS) frequently lowers the quality of life of ovarian cancer patients. Wrist...
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Changing serotypes of hand, foot and mouth disease in Shanghai, 2017–2019
BackgroundHand, foot, and mouth disease (HFMD) is a common reportable infectious disease that is highly contagious among children in China. This...
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A clinical scoring system for pediatric hand-foot-mouth disease
BackgroundThe aim of the present study was to develop a clinical scoring system for the diagnosis of hand-foot-mouth disease (HFMD) with improved...
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Study protocol of a single-arm phase 2 study evaluating the preventive effect of topical hydrocortisone for capecitabine-induced hand-foot syndrome in colorectal cancer patients receiving adjuvant chemotherapy with capecitabine plus oxaliplatin (T-CRACC study)
BackgroundsClinical evidence of the preventive effectiveness of medium-class topical corticosteroids for capecitabine-induced hand foot syndrome...
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The application of an allogeneic bone screw for osteosynthesis in hand and foot surgery: a case series
IntroductionThe allogeneic bone screw transplant is a new osteosynthesis device making the use of foreign fixation material obsolete for various...
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Intestinal microbiota has important effect on severity of hand foot and mouth disease in children
BackgroundThe incidence of hand foot and mouth disease (HFMD) has increased in recent years, making it a very common childhood illness worldwide. The...
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The role of dermocosmetics in the management of cancer-related skin toxicities: international expert consensus
Skin toxicities are very common in patients undergoing cancer treatment and have been found to occur with all types of cancer therapeutic...
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Healing refractory livedoid vasculopathy-related skin ulcers by ozone therapy: a case-based review
Chronic skin wounds represent a prominent etiological factor in the occurrence of non-traumatic foot amputations on a global scale and pose a...
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Pressure and Skin: A Review of Disease Entities Driven or Influenced by Mechanical Pressure
Skin perceives and reacts to external mechanical forces to create resistance against the external environment. Excessive or inappropriate stimuli of...
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Imaging features for the evaluation of skin and nail infections
Clinical manifestations of dermatological and musculoskeletal conditions can sometimes overlap, leading to confusion in diagnosis. Patients with nail...
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Electrospun skin dressings for diabetic wound treatment: a systematic review
AbstractDiabetes mellitus is a metabolic disease characterized by persistent hyperglycemia associated with a lack of insulin production or insulin...
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Expert Panel Review of Skin and Hair Dermatophytoses in an Era of Antifungal Resistance
Dermatophytoses are fungal infections of the skin, hair, and nails that affect approximately 25% of the global population. Occlusive clothing, living...
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Prevalence of phalangeal bone marrow edema on MRI before and during the COVID-19 pandemic and correlation with chilblain skin lesions
ObjectiveThe purpose of this study is to establish the prevalence bone marrow edema of the phalanges of the feet and hands before and during the...
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Risk factor analysis for anti-epidermal growth factor receptor monoclonal antibody–induced skin toxicities in real-world metastatic colorectal cancer treatment
PurposeAnti-epidermal growth factor receptor (anti-EGFR) monoclonal antibodies are effective in treating RAS wild-type metastatic colorectal cancer...
